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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Administration of RoActemra/Actemra (Tocilizumab) by Auto-injector Vs. Pre-filled Syringe in Healthy Volunteers

First Posted Date
2011-08-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
239
Registration Number
NCT01418989

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Anemic Patients With Chronic Kidney Disease (NORM)

Completed
Conditions
Anemia
Interventions
First Posted Date
2011-08-16
Last Posted Date
2017-07-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT01417377
Locations
🇵🇰

Fatima Memorial Hospital; Nephrology, Lahore, Pakistan

🇵🇰

Surgimed Hospital, Lahore, Pakistan

🇵🇰

Sheikh Zayed Hospital; Department of Nephrology, Lahore, Pakistan

and more 3 locations

An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Copegus (Ribavirin) in Participants With Chronic Hepatitis C (CHC), Genotype 2, 3, 1 or 4, Undergoing Opioid Maintenance Therapy

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2011-08-15
Last Posted Date
2017-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
88
Registration Number
NCT01416610
Locations
🇦🇹

Lkh-Univ. Klinikum Graz, Graz, Austria

🇦🇹

Lkh Hoergas-Enzenbach; Abt. Für Innere Medizin, Gratwein, Austria

🇦🇹

Lkh innsbruck - univ. Klinikum innsbruck - Tiroler landeskrankenanstalten ges.m.b.h.; Innere Medizin, Innsbruck, Austria

and more 7 locations

A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple Sclerosis

Phase 3
Completed
Conditions
Relapsing Multiple Sclerosis
Interventions
Drug: Interferon beta-1a
Drug: Ocrelizumab
Drug: Ocrelizumab-matching placebo
Drug: Interferon beta-1a-matching placebo
First Posted Date
2011-08-09
Last Posted Date
2024-03-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
835
Registration Number
NCT01412333
Locations
🇺🇸

Infinity Clinical Research, Hollywood, Florida, United States

🇺🇸

Stanford University Medical Center, Palo Alto, California, United States

🇺🇸

Advanced Neurosciences Research LLC, Fort Collins, Colorado, United States

and more 162 locations

A Study on The Effect of Multiple Doses of Activated Charcoal on The Pharmacokinetics of a Single Dose of RO4995819

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-08-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
26
Registration Number
NCT01409369

Participant Preference of Subcutaneous (SC) Versus Intravenous (IV) Herceptin (Trastuzumab) in Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer

Phase 2
Completed
Conditions
Breast Neoplasms
Interventions
Drug: Herceptin
Device: Single-Use Injection Device
First Posted Date
2011-07-25
Last Posted Date
2017-03-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
488
Registration Number
NCT01401166

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate Versus RoActemra/Actemra Monotherapy in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-07-22
Last Posted Date
2015-07-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
261
Registration Number
NCT01399697

An Observational Study of Avastin (Bevacizumab) in Combination With Xeloda (Capecitabine) And Oxaliplatin in Patients With Colorectal Cancer

Completed
Conditions
Colorectal Cancer
Interventions
Biological: Bevacizumab
Biological: Capecitabine
Drug: Oxaliplatin
First Posted Date
2011-07-21
Last Posted Date
2016-09-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT01399190

A Study of Danoprevir in Combination With Low-Dose Ritonavir in Healthy Subjects

First Posted Date
2011-07-20
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01398293

A Pharmacodynamic/Pharmacokinetic Study of Aleglitazar in Patients With Type 2 Diabetes Mellitus on Treatment With Lisinopril

Phase 1
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
First Posted Date
2011-07-20
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
55
Registration Number
NCT01398267
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