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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections With Insulin Lispro and Glargine

Not Applicable
Completed
Conditions
Diabetes Mellitus Type 1
Interventions
Device: Insulin pumps
First Posted Date
2007-05-03
Last Posted Date
2016-03-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
50
Registration Number
NCT00468754

A Study to Evaluate the Safety and Efficacy of MabThera (Rituximab) in Combination With Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Who Failed on Anti-Tumor Necrosis Factor Alpha Therapy

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: MabThera/Rituxan
Other: Placebo
First Posted Date
2007-05-02
Last Posted Date
2016-10-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
520
Registration Number
NCT00468546

A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies.

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Corticosteroid or NSAID
Dietary Supplement: Folate
First Posted Date
2007-04-19
Last Posted Date
2014-11-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT00462345

A Study of Subcutaneous Mircera for the Treatment of Anemia in Pre-Dialysis Participants With Chronic Kidney Disease.

Phase 3
Terminated
Conditions
Anemia
Interventions
First Posted Date
2007-04-19
Last Posted Date
2016-04-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
39
Registration Number
NCT00462384

A Study of Tarceva (Erlotinib) in Combination With Gemcitabine in Unresectable and/or Metastatic Cancer of the Pancreas: Relationship Between Skin Toxicity and Survival

Phase 2
Completed
Conditions
Pancreatic Cancer
Interventions
First Posted Date
2007-04-18
Last Posted Date
2015-10-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
153
Registration Number
NCT00461708

A Comparison of the Effects of Aleglitazar and Actos on Renal Function on Patients With Type 2 Diabetes.

Phase 2
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
First Posted Date
2007-04-17
Last Posted Date
2016-08-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
176
Registration Number
NCT00461006

A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure.

Phase 2
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
First Posted Date
2007-04-17
Last Posted Date
2016-08-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
14
Registration Number
NCT00461058

ESP Study: A Study to Assess the Effect of Adding Fuzeon (Enfuvirtide) to an Antiretroviral Regimen in Fuzeon-Naive Patients With Sustained HIV Viral Suppression.

Phase 4
Withdrawn
Conditions
HIV Infections
Interventions
Drug: Antiretroviral therapy
First Posted Date
2007-04-17
Last Posted Date
2016-08-24
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT00461266

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Lamivudine Resistant HBeAg-Negative Chronic Hepatitis B.

Phase 4
Terminated
Conditions
Hepatitis B, Chronic
Interventions
Drug: peginterferon alfa-2a (40KD) [PEGASYS]
First Posted Date
2007-04-17
Last Posted Date
2008-06-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT00460850

A Titration Study of a Glucagon-Like Peptide-1 (GLP-1) Analogue in Patients With Type 2 Diabetes Treated With Metformin.

Phase 2
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
First Posted Date
2007-04-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
133
Registration Number
NCT00460941
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