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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study to Evaluate the Safety and Efficacy of Adding Enfuvirtide to Oral Highly Active Antiretroviral Therapy (HAART) in Human Immunodeficiency Virus (HIV) Patients With Prior Treatment Experience

Phase 4
Completed
Conditions
HIV Infections
Interventions
Drug: Highly active antiretroviral treatment (HAART)
First Posted Date
2007-06-15
Last Posted Date
2015-08-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
47
Registration Number
NCT00487188

A Study of Bevacizumab (Avastin) in Combination With Capecitabine (Xeloda) in Elderly Patients With Metastatic Colorectal Cancer

Phase 3
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2007-06-12
Last Posted Date
2015-01-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
280
Registration Number
NCT00484939

The Individualized Management With Pegylated-interferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Offering Viral Eradication: A Study of Pegylated-interferon Alfa-2a Plus Ribavirin in Participants With Chronic Hepatitis C (CHC) Non-genotype 2/3 (IMPROVE)

Phase 3
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Pegylated-interferon Alfa-2a
First Posted Date
2007-06-08
Last Posted Date
2017-01-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
236
Registration Number
NCT00483938

A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease.

Phase 2
Withdrawn
Conditions
Pain
Neoplasm Metastasis
Bone Neoplasm
Interventions
First Posted Date
2007-05-24
Last Posted Date
2017-08-16
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT00478270

A Study of MabThera (Rituximab) in Patients With Idiopathic Thrombocytopenic Purpura.

Phase 2
Completed
Conditions
Idiopathic Thrombocytopenic Purpura
Interventions
First Posted Date
2007-05-21
Last Posted Date
2015-02-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
122
Registration Number
NCT00475423

A Study of Herceptin (Trastuzumab) in Women With Metastatic Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Drug: Taxane (docetaxel or paclitaxel)
First Posted Date
2007-05-21
Last Posted Date
2014-09-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
44
Registration Number
NCT00475670

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Ribavirin in Hemophiliac Patients With Chronic Hepatitis C.

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2007-05-17
Last Posted Date
2016-11-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
14
Registration Number
NCT00475072

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Chronic Hepatitis C and Chronic Renal Failure.

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2007-05-17
Last Posted Date
2016-07-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
27
Registration Number
NCT00474955

A Study of MabThera (Rituximab) Plus Standard Chemotherapy in Patients With Previously Untreated Mantle Cell Lymphoma.

Phase 2
Completed
Conditions
Mantle Cell Lymphoma
Interventions
Drug: First line chemotherapy
First Posted Date
2007-05-11
Last Posted Date
2017-08-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
48
Registration Number
NCT00472420
Locations
🇭🇺

University of Debrecen Medical and Health Science Center, Institute of Internal Medicine, Hematology, Debrecen, Hungary

🇭🇺

Kaposi Mor Teaching Hospital, Dept of Internal Medicine/Hematology, Kaposvar, Hungary

🇭🇺

Zala Megyei Korhaz; Ii. Belgyogyaszat, Zalaegerszeg, Hungary

and more 4 locations

Postoperative Canadian Oral Anticoagulation Self-management (Post-COAGS) Trial

Not Applicable
Withdrawn
Conditions
Cardiovascular Abnormalities
First Posted Date
2007-05-03
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT00468702
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