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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Dose-Escalating Study of Obinutuzumab in Patients With B-lymphocyte Antigen (CD20+) Malignant Disease (GAUGUIN)

Phase 1
Completed
Conditions
Lymphoma
Interventions
First Posted Date
2007-08-17
Last Posted Date
2016-10-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
134
Registration Number
NCT00517530

A Study of Tarceva (Erlotinib) and Gemcitabine in Treatment-Naive Patients With Advanced Non-Small Cell Lung Cancer.

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2007-08-17
Last Posted Date
2016-05-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
17
Registration Number
NCT00518011

A Study of MabThera (Rituximab) in Primary Central Nervous System Lymphoma.

Phase 2
Terminated
Conditions
Lymphoma
Interventions
First Posted Date
2007-08-17
Last Posted Date
2014-08-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
5
Registration Number
NCT00517699

A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Agents.

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2007-07-20
Last Posted Date
2014-08-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
36
Registration Number
NCT00504777

A Study of R3421 in Patients With Moderate to Severe Chronic Plaque Psoriasis.

Phase 2
Completed
Conditions
Psoriasis
Interventions
Drug: Placebo
Drug: RG3421 120mg
Drug: RG3421 20mg
First Posted Date
2007-07-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
66
Registration Number
NCT00504270

A Non-Comparative Study to Assess the Safety of MabThera (Rituximab) in Patients With Rheumatoid Arthritis.

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2007-07-18
Last Posted Date
2016-10-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
246
Registration Number
NCT00502996

A Study of Re-Treatment With MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2007-07-18
Last Posted Date
2017-08-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
193
Registration Number
NCT00502840
Locations
🇩🇪

Rheumapraxis - Dres. Edmund Edelmann, Gerhard Straeßner und Hans Bloching, Bad Aibling, Germany

🇩🇪

Campus Charité Mitte Charité Centrum 12. Med.Klinik Abt.Rheumatologie u.Klin.Immunologie, Berlin, Germany

🇩🇪

Praxis Dr. Silke Zinke, Berlin, Germany

and more 48 locations

A Study of Dipeptidyl-peptidase IV (DPP-IV) RO4876904 in Patients With Type 2 Diabetes.

Phase 2
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: Placebo
First Posted Date
2007-07-18
Last Posted Date
2016-08-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
289
Registration Number
NCT00502710

A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Malignant Bone Disease.

Phase 2
Completed
Conditions
Pain; Bone Neoplasms; Neoplasm Metastasis
Interventions
First Posted Date
2007-07-18
Last Posted Date
2014-01-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
13
Registration Number
NCT00502736

A Study of Xeloda (Capecitabine) as Adjuvant Monotherapy in Patients With Colon Cancer.

Phase 4
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2007-07-18
Last Posted Date
2015-09-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
228
Registration Number
NCT00502671
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