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Roche Holding AG

Roche Holding AG logo
πŸ‡¨πŸ‡­Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2013-07-19
Last Posted Date
2019-10-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
287
Registration Number
NCT01903993
Locations
πŸ‡ΊπŸ‡Έ

Kaiser Permanente - Vallejo, Vallejo, California, United States

πŸ‡ΊπŸ‡Έ

New York Oncology Hematology, P.C., Albany, New York, United States

πŸ‡ΊπŸ‡Έ

Wenatchee Valley Hospital & Clinics, Wenatchee, Washington, United States

and more 62 locations

A Study of Setrobuvir in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients With Genotype 1 Chronic Hepatitis C

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
Drug: placebo
First Posted Date
2013-07-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
283
Registration Number
NCT01903954

OPTIMA: An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Participants With Chronic Kidney Disease Stages 3 and 4 Not on Dialysis

Completed
Conditions
Anemia
First Posted Date
2013-07-18
Last Posted Date
2019-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
437
Registration Number
NCT01902628
Locations
πŸ‡¬πŸ‡·

Laiko General Hospital; Nephrology Div., Athens, Greece

πŸ‡¬πŸ‡·

General Hospital Of Athens G.Gennimatas; Nephrology, Athens, Greece

πŸ‡¬πŸ‡·

Uni Hospital of Alexandroupoli; Nephrology Dept., Alexandroupolis, Greece

and more 21 locations

An Observational Study of Induction Therapy With Fuzeon (Enfuvirtide) in Combination With Antiretroviral Drugs in Patients With HIV-1 Infection

Completed
Conditions
HIV Infections
First Posted Date
2013-07-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
58
Registration Number
NCT01902615

A Study of RO4995819 to Assess Bioavailability and Safety in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2013-07-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01901159

A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma

Phase 2
Terminated
Conditions
Basal Cell Carcinoma
Interventions
Drug: Placebo
First Posted Date
2013-07-12
Last Posted Date
2017-05-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT01898598
Locations
πŸ‡ΊπŸ‡Έ

Loma Linda University Medical Center, Loma Linda, California, United States

πŸ‡ΊπŸ‡Έ

Mayo Clinic, Scottsdale, Arizona, United States

πŸ‡ΊπŸ‡Έ

University of Minnesota, Minneapolis, Minnesota, United States

and more 18 locations

An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma

Phase 4
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2013-07-12
Last Posted Date
2020-01-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT01898585
Locations
πŸ‡ΏπŸ‡¦

Groote Schuur Hospital ( Uni of Capetown ); Oncology Dept, Cape Town, South Africa

πŸ‡ΏπŸ‡¦

Medical Oncology Centre of Rosebank; Oncology, Johannesburg, South Africa

πŸ‡ΏπŸ‡¦

Mary Potter Oncology Centre, Groenkloof, South Africa

and more 5 locations

A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular Carcinoma

Phase 1
Completed
Conditions
Carcinoma, Hepatocellular
Interventions
First Posted Date
2013-07-11
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
9
Registration Number
NCT01897038

A Study of RO6799477 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2013-07-09
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
27
Registration Number
NCT01893437
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