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Roche Holding AG

Roche Holding AG logo
๐Ÿ‡จ๐Ÿ‡ญSwitzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis

First Posted Date
2013-09-13
Last Posted Date
2018-11-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
100
Registration Number
NCT01941095
Locations
๐Ÿ‡ฌ๐Ÿ‡ท

Laiko General Hospital; Dept. of Pathophysiology-Uni of Athens, Athens, Greece

๐Ÿ‡ฌ๐Ÿ‡ท

Uni Hospital of Ioannina; Rheumatology, Ioannina, Greece

๐Ÿ‡ฌ๐Ÿ‡ท

General Hospital of Thessaloniki HIPPOKRATIO; Clinical Immunology Unit,2nd Dept of Internal Medicine, Thessaloniki, Greece

and more 7 locations

A Study of the Safety of Subcutaneously Administered Trastuzumab (Herceptin) in Participants With Early and Locally Advanced Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2013-09-12
Last Posted Date
2020-11-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
240
Registration Number
NCT01940497
Locations
๐Ÿ‡ฎ๐Ÿ‡น

Ospedale S.G.Calibita Fatebenefratelli; Unitร  Operativa Oncologia, Roma, Lazio, Italy

๐Ÿ‡ฎ๐Ÿ‡น

Campus Universitario S.Venuta; Centro Oncologico T.Campanella, Catanzaro, Calabria, Italy

๐Ÿ‡ฎ๐Ÿ‡น

Ospedale San Carlo; Day Hospital Oncologia Medica, Potenza, Basilicata, Italy

and more 51 locations

An Observational Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) in Stage V Chronic Kidney Disease Participants on Hemodialysis

Completed
Conditions
Anemia
Interventions
Drug: Methoxy polyethylene glycol epoetin beta
First Posted Date
2013-09-12
Last Posted Date
2017-07-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
98
Registration Number
NCT01940484
Locations
๐Ÿ‡ฟ๐Ÿ‡ฆ

Donald Gordon Medical Centre, Johannesburg, South Africa

๐Ÿ‡ฟ๐Ÿ‡ฆ

Universitas Private Hospital, Bloemfontein, South Africa

๐Ÿ‡ฟ๐Ÿ‡ฆ

Glynnwood Hospital, Benoni, South Africa

and more 7 locations

A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2013-09-12
Last Posted Date
2016-12-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT01940510

An Interventional Study of Avastin (Bevacizumab) in Patients With Advanced/Metastatic Epithelial Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Phase 4
Active, not recruiting
Conditions
Ovarian Neoplasms
Peritoneal Neoplasms
Fallopian Tube Neoplasms
Interventions
First Posted Date
2013-08-30
Last Posted Date
2025-03-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
100
Registration Number
NCT01932125
Locations
๐Ÿ‡ฎ๐Ÿ‡ณ

Rajiv Gandhi Cancer Inst.&Research Center, New Delhi, Delhi, India

๐Ÿ‡ฎ๐Ÿ‡ณ

Manipal Hospital, Bangalore, Karnataka, India

๐Ÿ‡ฎ๐Ÿ‡ณ

HealthCare Global Enterprises Limited, Banglore, Karnataka, India

and more 10 locations

A Study of Subcutaneously Administered Herceptin (Trastuzumab) in Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Early Breast Cancer

Phase 2
Terminated
Conditions
Breast Cancer
Interventions
First Posted Date
2013-08-27
Last Posted Date
2014-09-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2
Registration Number
NCT01928615

A Study of Subcutaneous At Home Administration of Trastuzumab (Herceptin) in Participants With Human Epidermal Growth Factor Receptor 2-positive (HER2+) Early Breast Cancer (eBC)

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2013-08-21
Last Posted Date
2019-09-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
102
Registration Number
NCT01926886
Locations
๐Ÿ‡ฎ๐Ÿ‡ฑ

Soroka Medical Center; Oncology Dept, Beer Sheva, Israel

๐Ÿ‡ฎ๐Ÿ‡ฑ

Rabin MC; Davidof Center - Oncology Institute, Petach Tikva, Israel

๐Ÿ‡ง๐Ÿ‡ช

AZ Maria Middelares, Gent, Belgium

and more 20 locations

A Screening Study To Assess The Cognition Status in Healthy Volunteers

Completed
Conditions
Healthy Volunteer
First Posted Date
2013-08-21
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
240
Registration Number
NCT01926873

A PET Study With RO5545965 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Schizophrenia
Interventions
First Posted Date
2013-08-14
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
9
Registration Number
NCT01923025

A Study in Participants With Asthma Initiating Treatment With Omalizumab (Xolair)

Phase 4
Completed
Conditions
Asthma
Interventions
First Posted Date
2013-08-14
Last Posted Date
2017-12-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
806
Registration Number
NCT01922037
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Rochester, Rochester, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Rush University Medical Center, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Chest Medicine Consultants, Chicago, Illinois, United States

and more 140 locations
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