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Roche Holding AG

Roche Holding AG logo
πŸ‡¨πŸ‡­Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of RO4995819 to Assess Bioavailability and Safety in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4995819
First Posted Date
2013-07-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01901159

A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
Drug: RO5503781
Drug: posaconazole
First Posted Date
2013-07-17
Last Posted Date
2015-08-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
61
Registration Number
NCT01901172

An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma

Phase 4
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2013-07-12
Last Posted Date
2020-01-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT01898585
Locations
πŸ‡ΏπŸ‡¦

Groote Schuur Hospital ( Uni of Capetown ); Oncology Dept, Cape Town, South Africa

πŸ‡ΏπŸ‡¦

Medical Oncology Centre of Rosebank; Oncology, Johannesburg, South Africa

πŸ‡ΏπŸ‡¦

Mary Potter Oncology Centre, Groenkloof, South Africa

and more 5 locations

A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma

Phase 2
Terminated
Conditions
Basal Cell Carcinoma
Interventions
Drug: Placebo
Drug: Vismodegib
First Posted Date
2013-07-12
Last Posted Date
2017-05-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT01898598
Locations
πŸ‡ΊπŸ‡Έ

Loma Linda University Medical Center, Loma Linda, California, United States

πŸ‡ΊπŸ‡Έ

Mayo Clinic, Scottsdale, Arizona, United States

πŸ‡ΊπŸ‡Έ

University of Minnesota, Minneapolis, Minnesota, United States

and more 18 locations

A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular Carcinoma

Phase 1
Completed
Conditions
Carcinoma, Hepatocellular
Interventions
First Posted Date
2013-07-11
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
9
Registration Number
NCT01897038

A Study of RO6799477 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO6799477
First Posted Date
2013-07-09
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
27
Registration Number
NCT01893437

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Phase 3
Withdrawn
Conditions
Diabetes Mellitus Type 2, Kidney Disease, Chronic
Interventions
Drug: Aleglitazar
Drug: Placebo
First Posted Date
2013-07-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT01893242

An Observational Study of Avastin (Bevacizumab) in Elderly Patients With Non-Squamous Non-Small Cell Lung Cancer in Clinical Practice

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2013-07-08
Last Posted Date
2018-05-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
279
Registration Number
NCT01893268
Locations
πŸ‡«πŸ‡·

Clinique Du Docteur Calabet; Cromg, Agen, France

πŸ‡«πŸ‡·

Poly Parc Rambot La Provencale; Chimiotherapie Ambulatoire, Aix En Provence, France

πŸ‡«πŸ‡·

HOPITAL JEAN MINJOZ; Oncologie, Besancon, France

and more 82 locations

A Non-Interventional Study in Patients With Rheumatoid Arthritis Who Are Treated With RoActemra/Actemra (Tocilizumab)

Withdrawn
Conditions
Rheumatoid Arthritis
First Posted Date
2013-07-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT01893255

A Non-Interventional Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Patients With Chronic Kidney Disease Not on Dialysis

Conditions
Anemia
First Posted Date
2013-07-04
Last Posted Date
2016-10-27
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT01892202
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