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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of RO6870868 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: placebo
Drug: RO6870868
First Posted Date
2013-07-30
Last Posted Date
2018-07-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT01911611

A Study of Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic Melanoma

Phase 1
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2013-07-29
Last Posted Date
2019-05-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
46
Registration Number
NCT01910181
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, China

🇨🇳

Sun Yet-sen University Cancer Center, Guangzhou, China

A Study to Collect Blood Samples From Patients With Spinal Muscular Atrophy for Biomarker Analysis

Completed
Conditions
Muscular Atrophy, Spinal
First Posted Date
2013-07-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
36
Registration Number
NCT01910168

A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia

Phase 3
Completed
Conditions
Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2013-07-23
Last Posted Date
2019-10-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
979
Registration Number
NCT01905943
Locations
🇧🇷

Hospital das Clinicas - UFRGS, Porto Alegre, RS, Brazil

🇧🇷

Hospital de Cancer de Barretos, Barretos, SP, Brazil

🇧🇷

Hospital Amaral Carvalho, Jau, SP, Brazil

and more 171 locations

A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis

Phase 1
Completed
Conditions
Juvenile Idiopathic Arthritis
Interventions
First Posted Date
2013-07-22
Last Posted Date
2017-11-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01904292
Locations
🇺🇸

Hackensack University Medical Center; Pediatric Rheumatology, Hackensack, New Jersey, United States

🇺🇸

Ann & Robert H. Lurie Children's Hospital of Chicago; Division of Rheumatology, Chicago, Illinois, United States

🇺🇸

Cleveland Clinic Fndn, Cleveland, Ohio, United States

and more 39 locations

A Study of Subcutaneously (SC) Administered Tocilizumab (TCZ) in Participants With Polyarticular-Course Juvenile Idiopathic Arthritis (pJIA)

Phase 1
Completed
Conditions
Juvenile Idiopathic Arthritis
Interventions
First Posted Date
2013-07-22
Last Posted Date
2017-06-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01904279

A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2013-07-19
Last Posted Date
2019-10-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
287
Registration Number
NCT01903993
Locations
🇺🇸

Kaiser Permanente - Vallejo, Vallejo, California, United States

🇺🇸

New York Oncology Hematology, P.C., Albany, New York, United States

🇺🇸

Wenatchee Valley Hospital & Clinics, Wenatchee, Washington, United States

and more 62 locations

A Study of Setrobuvir in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients With Genotype 1 Chronic Hepatitis C

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
Drug: placebo
Drug: ribavirin [Copegus]
Drug: setrobuvir
First Posted Date
2013-07-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
283
Registration Number
NCT01903954

OPTIMA: An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Participants With Chronic Kidney Disease Stages 3 and 4 Not on Dialysis

Completed
Conditions
Anemia
First Posted Date
2013-07-18
Last Posted Date
2019-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
437
Registration Number
NCT01902628
Locations
🇬🇷

Laiko General Hospital; Nephrology Div., Athens, Greece

🇬🇷

General Hospital Of Athens G.Gennimatas; Nephrology, Athens, Greece

🇬🇷

Uni Hospital of Alexandroupoli; Nephrology Dept., Alexandroupolis, Greece

and more 21 locations

An Observational Study of Induction Therapy With Fuzeon (Enfuvirtide) in Combination With Antiretroviral Drugs in Patients With HIV-1 Infection

Completed
Conditions
HIV Infections
First Posted Date
2013-07-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
58
Registration Number
NCT01902615
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