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BICYCLETX LIMITED

🇬🇧United Kingdom
Ownership
-
Employees
-
Market Cap
-
Website

Clinical Trials

13

Active:4
Completed:0

Trial Phases

2 Phases

Phase 1:8
Phase 2:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (12 trials with phase data)• Click on a phase to view related trials

Phase 1
8 (66.7%)
Phase 2
3 (25.0%)
phase_2_3
1 (8.3%)

Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer

Phase 2
Not yet recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
Drug: Zelenectide pevedotin (BT8009)
First Posted Date
2025-04-18
Last Posted Date
2025-04-18
Lead Sponsor
BicycleTx Limited
Target Recruit Count
73
Registration Number
NCT06933329

Study to Assess Clinical Activity of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

Phase 2
Recruiting
Conditions
Breast Cancer
Interventions
Drug: Zelenectide pevedotin (BT8009)
First Posted Date
2025-02-21
Last Posted Date
2025-06-26
Lead Sponsor
BicycleTx Limited
Target Recruit Count
66
Registration Number
NCT06840483
Locations
🇺🇸

Yale New Haven Hospital - Yale Cancer Center, New Haven, Connecticut, United States

🇺🇸

Siteman Cancer Center, Saint Louis, Missouri, United States

🇺🇸

Compass Oncology - Rose Quarter Cancer Center, Portland, Oregon, United States

and more 8 locations

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

Phase 2
Recruiting
Conditions
Metastatic Urothelial Cancer
Interventions
First Posted Date
2024-01-26
Last Posted Date
2025-06-22
Lead Sponsor
BicycleTx Limited
Target Recruit Count
956
Registration Number
NCT06225596
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

🇺🇸

Virginia K. Crosson Cancer Center at St. Jude Medical Center, Fullerton, California, United States

🇺🇸

University of California - Irvine Medical Center, Orange, California, United States

and more 166 locations

Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression

Phase 1
Active, not recruiting
Conditions
Advanced Solid Tumor
Interventions
First Posted Date
2021-12-20
Last Posted Date
2025-02-04
Lead Sponsor
BicycleTx Limited
Target Recruit Count
200
Registration Number
NCT05163041
Locations
🇺🇸

State University of Iowa, Iowa City, Iowa, United States

🇺🇸

Columbia University Irving Medical Center, New York, New York, United States

🇺🇸

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

and more 6 locations

Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies

Phase 1
Recruiting
Conditions
Urinary Bladder Neoplasm
Triple Negative Breast Neoplasms
Hormone Receptor Positive, HER2-negative Neoplasms
Hormone Receptor Positive, HER2-low Neoplasms
Breast Neoplasms
Non-Small-Cell Lung Neoplasms
Ovarian Neoplasm
Advanced Solid Tumor
Interventions
First Posted Date
2020-09-23
Last Posted Date
2024-04-23
Lead Sponsor
BicycleTx Limited
Target Recruit Count
329
Registration Number
NCT04561362
Locations
🇺🇸

Sarah Cannon Research Institute at HealthONE, Denver, Colorado, United States

🇺🇸

Ocala Oncology Center, Ocala, Florida, United States

🇺🇸

Advent Health, Orlando, Florida, United States

and more 26 locations
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