X4 Pharmaceuticals, Inc.

X4 Pharmaceuticals, Inc. logo
๐Ÿ‡บ๐Ÿ‡ธUnited States
Ownership
Public
Established
2014-01-01
Employees
93
Market Cap
$117.9M
Website
http://www.x4pharma.com

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2023-09-28
Last Posted Date
2024-07-03
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
150
Registration Number
NCT06056297
Locations
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LTD "Israeli-Georgian Medical Research Clinic Healthycore", Tbilisi, Georgia

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LEPL The First University Clinic of Tbilisi State Medical University, Tbilisi, Georgia

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Hospital Universitario Son Espases, Mallorca, Spain

and more 9 locations

A Study of Mavorixafor in Combination With Ibrutinib in Participants With Waldenstrom's Macroglobulinemia (WM) Whose Tumors Express Mutations in MYD88 and CXCR4

First Posted Date
2020-02-18
Last Posted Date
2024-08-27
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
16
Registration Number
NCT04274738
Locations
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Dana Farber Cancer Institute, Boston, Massachusetts, United States

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Mass General Hospital Cancer Center, Boston, Massachusetts, United States

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University of Athens, Athens, Greece

and more 2 locations

A Study of Mavorixafor in Participants With Congenital Neutropenia and Chronic Idiopathic Neutropenia Disorders

Phase 1
Completed
Conditions
Interventions
First Posted Date
2019-11-06
Last Posted Date
2024-11-15
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT04154488
Locations
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Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

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University of Washington, Seattle, Washington, United States

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USF Health Department of Pediatrics, Saint Petersburg, Florida, United States

and more 4 locations

Efficacy and Safety Study of Mavorixafor in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-06-21
Last Posted Date
2024-05-02
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
31
Registration Number
NCT03995108
Locations
๐Ÿ‡ฆ๐Ÿ‡บ

Wesley Hospital, Auchenflower, Queensland, Australia

๐Ÿ‡ญ๐Ÿ‡บ

University of Debrecen, Affiliated Department of Infectology, Debrecen, Hajdu-Bihar, Hungary

๐Ÿ‡ซ๐Ÿ‡ท

CHU de Lyon, Institut d'Hematologie et d'Oncologie Pediatrique, Lyon, Rhne, France

and more 20 locations

A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome

Withdrawn
Conditions
First Posted Date
2017-03-22
Last Posted Date
2018-12-07
Lead Sponsor
X4 Pharmaceuticals
Registration Number
NCT03087370

A Dose Determination and Safety Study of X4P-001 (Mavorixafor) in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-12-29
Last Posted Date
2024-10-30
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
8
Registration Number
NCT03005327
Locations
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University of Washington Medical Center, Seattle, Washington, United States

๐Ÿ‡ฆ๐Ÿ‡บ

St. Vincent's Hospital, Fitzroy, Victoria, Australia

Addition of X4P-001 to Nivolumab Treatment in Participants With Renal Cell Carcinoma

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2016-10-04
Last Posted Date
2022-12-29
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
9
Registration Number
NCT02923531

X4P-001 and Pembrolizumab in Patients With Advanced Melanoma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-07-06
Last Posted Date
2020-07-07
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
16
Registration Number
NCT02823405
Locations
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Clinical Site, Salt Lake City, Utah, United States

A Study Comparing Once-Daily vs. Twice-Daily Dosing of X4P-001 in Healthy Volunteers

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2016-02-12
Last Posted Date
2018-12-07
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
15
Registration Number
NCT02680782
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Covance CRU, Inc., Daytona Beach, Florida, United States

Trial of X4P-001 in Participants With Advanced Renal Cell Carcinoma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-01-29
Last Posted Date
2024-10-03
Lead Sponsor
X4 Pharmaceuticals
Target Recruit Count
74
Registration Number
NCT02667886
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