University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Providing Oxygen During Intubation in the NICU Trial

Not Applicable

Recruiting

Conditions: Tracheal Intubation Morbidity
Neonatal Respiratory Failure

Interventions: Procedure: Apneic Oxygenation
Procedure: Standard of Care

First Posted Date: 2022-07-11

Last Posted Date: 2025-05-25

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 110

Registration Number: NCT05451953

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

Not Applicable

Recruiting

Conditions: Extubation Failure
Bronchopulmonary Dysplasia
Death

Interventions: Device: NIV-NAVA
Device: NS-NIPPV

First Posted Date: 2022-07-06

Last Posted Date: 2024-03-01

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 478

Registration Number: NCT05446272

Locations: 🇺🇸
Children's Mercy Hospital, Kansas City, Missouri, United States
🇺🇸
Levine Children's Hospital, Charlotte, North Carolina, United States
🇺🇸
Atrial Health Brenner Children's Hospital( Wake Forest), Winston-Salem, North Carolina, United States

and more 17 locations

CART-38 in Adult AML and MM Patients

Phase 1

Active, not recruiting

Conditions: Acute Myeloid Leukemia (AML)
Multiple Myeloma (MM)

Interventions: Drug: 3x10(6) CART-38 cellls
Drug: 7x10(5) CART-38 cells
Drug: 7x10(6) CART-38 cells
Drug: 3x10(7) CART-38 cells
Drug: Cyclophosphamide
Drug: Fludarabine

First Posted Date: 2022-07-05

Last Posted Date: 2025-03-28

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 36

Registration Number: NCT05442580

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients

Not Applicable

Completed

Conditions: Aging
Surgery

Interventions: Behavioral: Patient Informational Letter
Behavioral: Peer Comparison Feedback

First Posted Date: 2022-06-29

Last Posted Date: 2024-01-18

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 517611

Registration Number: NCT05436392

Locations: 🇺🇸
US Anesthesia Partners, Dallas, Texas, United States

Decoding and Modulating Affective Brain States

Not Applicable

Recruiting

Conditions: Rumination
Major Depressive Disorder
Anxiety

Interventions: Device: Transcranial Magnetic Stimulation

First Posted Date: 2022-06-29

Last Posted Date: 2024-07-22

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 40

Registration Number: NCT05437705

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

ACE2 Chewing Gum on SARS-CoV-2 Viral Load (COVID 19)

Phase 1

Withdrawn

Conditions: SARS-CoV-2

Interventions: Other: Placebo Chewing Gum
Drug: ACE2 Chewing Gum

First Posted Date: 2022-06-27

Last Posted Date: 2025-03-30

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 40

Registration Number: NCT05433181

Locations: 🇺🇸
Infectious Diseases Clinical Trial Unit, Philadelphia, Pennsylvania, United States

Online Food and Beverage Labels and Vending Machine Selections

Not Applicable

Completed

Conditions: Obesity
Weight Gain
Food Preferences

Interventions: Behavioral: Exposure to calorie information
Behavioral: Exposure to healthy labels only
Behavioral: Exposure to healthiness information
Behavioral: Exposure to physical activity equivalents
Behavioral: Exposure to "high in" nutrient warning labels

First Posted Date: 2022-06-27

Last Posted Date: 2023-12-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 8145

Registration Number: NCT05432271

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Way To Drive Validation Study

Completed

Conditions: Validity
Driving Behaviors
Distracted Driving

First Posted Date: 2022-06-16

Last Posted Date: 2023-06-05

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 62

Registration Number: NCT05422586

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Ibudilast for Treating Alcohol Use Disorder

Phase 2

Active, not recruiting

Conditions: Alcohol Use Disorder (AUD)
Alcoholism

Interventions: Drug: Ibudilast
Behavioral: Medical management
Drug: Placebo

First Posted Date: 2022-06-10

Last Posted Date: 2025-05-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 50

Registration Number: NCT05414240

Locations: 🇺🇸
University of Pennsylvania Center for Studies of Addiction, Philadelphia, Pennsylvania, United States

Utilization of Hepatitis B Virus NAT+ Donors for Hepatitis B Vaccinated Lung Transplant Candidates

Phase 2

Withdrawn

Conditions: Hepatitis B
Lung Transplant

Interventions: Drug: Hepatitis B Immune Globulin and entecavir, tenofovir disoproxil, or tenofovir alafenamide

First Posted Date: 2022-06-03

Last Posted Date: 2024-08-06

Lead Sponsor: University of Pennsylvania

Registration Number: NCT05404919

Locations: 🇺🇸
Hospital of University of Pennsylvania, Philadelphia, Pennsylvania, United States

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