University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Diet and Fecal Incontinence in Senior Women

Not Applicable

Completed

Conditions: Accidental Bowel Leakage
Fecal Incontinence
Incontinence
Bowel Incontinence

Interventions: Behavioral: Diet Modification Pilot Program (DPM)

First Posted Date: 2018-04-27

Last Posted Date: 2021-01-25

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 55

Registration Number: NCT03510052

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition

Phase 3

Suspended

Conditions: Pre-diabetic
Diabetes Mellitus, Type 2
Hypertension
Elevated Blood Pressure

Interventions: Drug: Sacubitril/Valsartan 200mg (blinded)
Drug: Valsartan 160mg (blinded)

First Posted Date: 2018-04-26

Last Posted Date: 2024-08-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 25

Registration Number: NCT03508739

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

A Study of Human Multi-Sensory Integration

Phase 2

Suspended

Conditions: Anesthesia Awareness

Interventions: Drug: Ketamine Injectable Product
Drug: Propofol

First Posted Date: 2018-04-13

Last Posted Date: 2023-02-08

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 40

Registration Number: NCT03498391

Locations: 🇺🇸
University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, United States

Zaleplon in HIV Patients With Depression

Phase 2

Completed

Conditions: HIV/AIDS
Clinical Depression

Interventions: Drug: Zaleplon

First Posted Date: 2018-04-05

Last Posted Date: 2018-10-16

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT03489304

Locations: 🇺🇸
Mood & Anxiety Disorders Research and Treatment Program, Philadelphia, Pennsylvania, United States

Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

Phase 2

Recruiting

Conditions: Churg-Strauss Syndrome (CSS)
Polyarteritis Nodosa
Giant Cell Arteritis
Granulomatosis With Polyangiitis
Eosinophilic Granulomatosis With Polyangiitis (EGPA)
Microscopic Polyangiitis
Takayasu Arteritis

Interventions: Other: Placebo Comparator
Drug: Naltrexone Hydrochloride

First Posted Date: 2018-03-29

Last Posted Date: 2025-04-11

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 36

Registration Number: NCT03482479

Locations: 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
University of Utah, Salt Lake City, Utah, United States

and more 4 locations

Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS)

Phase 2

Completed

Conditions: Aortic Valve Stenosis

Interventions: Drug: Potassium Nitrate
Drug: Potassium Chloride

First Posted Date: 2018-03-29

Last Posted Date: 2020-06-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 5

Registration Number: NCT03483051

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Low Dose Fat-Induced Insulin Resistance

Early Phase 1

Recruiting

Conditions: Diabetes Mellitus, Type 2
Insulin Resistance
Insulin Sensitivity

Interventions: Drug: Intralipid, 20% Intravenous Emulsion

First Posted Date: 2018-03-27

Last Posted Date: 2025-03-11

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 12

Registration Number: NCT03479671

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Acute Effects of E-Cigarette Aerosol Inhalation

Early Phase 1

Completed

Conditions: Endothelial Dysfunction
Biochemical Markers

Interventions: Drug: Electronic Cigarette Aerosol

First Posted Date: 2018-03-27

Last Posted Date: 2024-05-08

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 31

Registration Number: NCT03479203

Locations: 🇺🇸
University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States

Serial SMS Reminders and an Opt-out Mailed FIT Kits to Improve Colorectal Screening Participation: A Single Center RCT

Not Applicable

Completed

Conditions: Colon Cancer
Bowel Cancer

Interventions: Behavioral: Serial text messages and mailed FIT kit

First Posted Date: 2018-03-27

Last Posted Date: 2019-07-22

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 440

Registration Number: NCT03479645

Locations: 🇺🇸
Family Practice and Councelling Network, Philadelphia, Pennsylvania, United States

Perfusion Enhancement With Respiratory Impedance in Stroke (PERI-Stroke)

Not Applicable

Completed

Conditions: Stroke

Interventions: Other: Respiratory Impedance (RI)

First Posted Date: 2018-03-26

Last Posted Date: 2024-02-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT03476954

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

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