University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

The Longitudinal Ovarian Reserve Study

Completed

Conditions: Effects of Chemotherapy

First Posted Date: 2015-03-23

Last Posted Date: 2016-08-22

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT02395341

Locations: 🇺🇸
Penn Reproductive Research Unit, 3701 Market Street, Suite 810, Philadelphia, Pennsylvania, United States
🇺🇸
Penn Medicine at Radnor, 250 King of Prussia Road, Radnor, Pennsylvania, United States

Stress and Inflammation in Late-Life Depression

Phase 4

Completed

Conditions: Depression
Inflammation

Interventions: Drug: Escitalopram + Celecoxib
Drug: Escitalopram + Placebo

First Posted Date: 2015-03-17

Last Posted Date: 2023-10-02

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 119

Registration Number: NCT02389465

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

A Phase I Study of T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728mR in HIV-Infected Patients

Phase 1

Completed

Conditions: Human Immunodeficiency Virus (HIV)

Interventions: Drug: ZFN Modified CD4+ T Cells
Drug: Cyclophosphamide

First Posted Date: 2015-03-17

Last Posted Date: 2019-04-10

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 14

Registration Number: NCT02388594

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

CART-meso Long-term Follow-up

Completed

Conditions: Subjects Who Have Received Lentiviral-based CART-meso Therapy

Interventions: Biological: lentiviral-based CART meso therapy

First Posted Date: 2015-03-17

Last Posted Date: 2019-09-19

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 10

Registration Number: NCT02388828

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Lifestyle Modification and Lorcaserin for Weight Loss Maintenance

Not Applicable

Completed

Conditions: Obesity

Interventions: Drug: Lorcaserin
Drug: Placebo

First Posted Date: 2015-03-17

Last Posted Date: 2018-06-11

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 137

Registration Number: NCT02388568

Locations: 🇺🇸
University of Pennsylvania Center for Weight and Eating Disorders, Philadelphia, Pennsylvania, United States

Study of Radiotracer [18F]Fluortriopride ([18F]FTP) by PET/CT

Phase 1

Active, not recruiting

Conditions: Healthy

Interventions: Drug: [18F]Fluortriopride

First Posted Date: 2015-03-04

Last Posted Date: 2024-08-23

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 29

Registration Number: NCT02379338

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Prevention and Management of Food Allergies

Not Applicable

Completed

Conditions: Food Allergy
Empathy

Interventions: Other: Photograph

First Posted Date: 2015-03-03

Last Posted Date: 2018-06-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 187

Registration Number: NCT02377284

Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell Therapy

Phase 1

Completed

Conditions: Diffuse Large Cell Lymphoma
Acute Lymphocytic Leukemia

Interventions: Biological: huCART19

First Posted Date: 2015-02-27

Last Posted Date: 2021-09-23

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 81

Registration Number: NCT02374333

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers

Phase 2

Completed

Conditions: Alcohol Use Disorder (AUD)
Alcoholism

Interventions: Behavioral: Medical Management
Drug: Topiramate
Drug: Inactive Placebo

First Posted Date: 2015-02-26

Last Posted Date: 2022-01-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 320

Registration Number: NCT02371889

Locations: 🇺🇸
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States
🇺🇸
University of Pennsylvania Treatment Research Center, Philadelphia, Pennsylvania, United States

Short-course Methenamine Hippurate for Prevention of Post-operative UTI

Not Applicable

Completed

Conditions: Catheter-Related Infections
Urinary Tract Infections

Interventions: Drug: methenamine hippurate
Drug: Ciprofloxacin

First Posted Date: 2015-02-09

Last Posted Date: 2022-02-25

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 201

Registration Number: NCT02358993

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States
🇺🇸
Pennsylvania Hospital, Philadelphia, Pennsylvania, United States

and more 1 locations

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