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NATIONAL INSTITUTES OF HEALTH

NATIONAL INSTITUTES OF HEALTH logo
🇺🇸United States
Ownership
Subsidiary, Private
Established
1948-01-01
Employees
1K
Market Cap
-
Website
http://www.nidcr.nih.gov

Apolizumab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Phase 2
Completed
Conditions
Noncontiguous Stage II Small Lymphocytic Lymphoma
Recurrent Small Lymphocytic Lymphoma
Refractory Chronic Lymphocytic Leukemia
Stage III Small Lymphocytic Lymphoma
Stage IV Small Lymphocytic Lymphoma
Interventions
Biological: apolizumab
Other: laboratory biomarker analysis
Other: pharmacological study
First Posted Date
2004-08-05
Last Posted Date
2013-07-16
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
32
Registration Number
NCT00089154
Locations
🇺🇸

Chronic Lymphocytic Leukemia Research Consortium (CRC), La Jolla, California, United States

🇺🇸

Ohio State University Medical Center, Columbus, Ohio, United States

Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Phase 3
Completed
Conditions
Adenocarcinoma of the Pancreas
Recurrent Pancreatic Cancer
Stage II Pancreatic Cancer
Stage III Pancreatic Cancer
Stage IV Pancreatic Cancer
Interventions
Biological: bevacizumab
Other: placebo
Other: laboratory biomarker analysis
Other: pharmacogenomic studies
Other: pharmacological study
First Posted Date
2004-08-05
Last Posted Date
2013-06-05
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
590
Registration Number
NCT00088894
Locations
🇺🇸

Cancer and Leukemia Group B, Chicago, Illinois, United States

Alemtuzumab With or Without Methotrexate and Mercaptopurine in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia

Phase 2
Completed
Conditions
Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions
First Posted Date
2004-08-05
Last Posted Date
2013-06-05
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
25
Registration Number
NCT00089349
Locations
🇺🇸

COG Phase I Consortium, Arcadia, California, United States

Cilengitide in Treating Patients With Acute Myeloid Leukemia

Phase 2
Terminated
Conditions
Adult Acute Basophilic Leukemia
Adult Acute Eosinophilic Leukemia
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Adult Acute Myeloid Leukemia in Remission
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)
Interventions
First Posted Date
2004-08-05
Last Posted Date
2013-01-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
70
Registration Number
NCT00089388
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Decitabine in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas

Phase 1
Terminated
Conditions
Hematopoietic/Lymphoid Cancer
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Other: pharmacological study
Other: laboratory biomarker analysis
First Posted Date
2004-08-05
Last Posted Date
2013-01-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
42
Registration Number
NCT00089089
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors

Phase 1
Completed
Conditions
Male Breast Cancer
Recurrent Adenoid Cystic Carcinoma of the Oral Cavity
Recurrent Basal Cell Carcinoma of the Lip
Recurrent Breast Cancer
Recurrent Colon Cancer
Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity
Recurrent Gastric Cancer
Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity
Recurrent Lymphoepithelioma of the Nasopharynx
Recurrent Lymphoepithelioma of the Oropharynx
Interventions
Other: laboratory biomarker analysis
Other: pharmacological study
First Posted Date
2004-08-05
Last Posted Date
2013-04-10
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
30
Registration Number
NCT00089362
Locations
🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Celecoxib and Erlotinib in Treating Former Smokers With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
Stage IIIB Non-small Cell Lung Cancer
Stage IV Non-small Cell Lung Cancer
Recurrent Non-small Cell Lung Cancer
Interventions
Other: laboratory biomarker analysis
First Posted Date
2004-08-05
Last Posted Date
2014-10-10
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
45
Registration Number
NCT00088959
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma

Phase 1
Terminated
Conditions
B-cell Chronic Lymphocytic Leukemia
Cutaneous B-cell Non-Hodgkin Lymphoma
Adult Grade III Lymphomatoid Granulomatosis
Recurrent Grade 1 Follicular Lymphoma
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Recurrent Adult Grade III Lymphomatoid Granulomatosis
Recurrent Adult Hodgkin Lymphoma
Recurrent Grade 2 Follicular Lymphoma
Recurrent Marginal Zone Lymphoma
Small Intestine Lymphoma
Interventions
Biological: ipilimumab
Other: laboratory biomarker analysis
First Posted Date
2004-08-05
Last Posted Date
2014-05-30
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
18
Registration Number
NCT00089076
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Bortezomib and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Previously Untreated Symptomatic Multiple Myeloma

Phase 2
Completed
Conditions
DS Stage II Plasma Cell Myeloma
DS Stage III Plasma Cell Myeloma
DS Stage I Plasma Cell Myeloma
Interventions
First Posted Date
2004-08-05
Last Posted Date
2019-09-23
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
55
Registration Number
NCT00088855
Locations
🇺🇸

Novant Health Presbyterian Medical Center, Charlotte, North Carolina, United States

🇺🇸

Danville Regional Medical Center, Danville, Virginia, United States

🇺🇸

Frisbie Hospital, Rochester, New Hampshire, United States

and more 22 locations

Rituximab, Combination Chemotherapy, and 90-Yttrium Ibritumomab Tiuxetan for Patients With Stage I or II Non-Hodgkin's Lymphoma

Phase 2
Terminated
Conditions
Splenic Marginal Zone Lymphoma
Contiguous Stage II Adult Diffuse Large Cell Lymphoma
Testicular Lymphoma
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Nodal Marginal Zone B-cell Lymphoma
Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma
Stage I Adult Diffuse Large Cell Lymphoma
Waldenström Macroglobulinemia
Interventions
Biological: rituximab
Radiation: indium In 111 ibritumomab tiuxetan
Radiation: radiation therapy
Procedure: positron emission tomography
First Posted Date
2004-08-05
Last Posted Date
2017-05-25
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
62
Registration Number
NCT00088881
Locations
🇺🇸

Eastern Cooperative Oncology Group, Boston, Massachusetts, United States

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