MedPath

argenx

🇧🇪Belgium
Ownership
-
Established
2008-01-01
Employees
-
Market Cap
$31.2B
Website
https://www.argenx.com/

Open-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's Syndrome

Phase 2
Completed
Conditions
Primary Sjögren's Syndrome
Interventions
First Posted Date
2024-01-12
Last Posted Date
2025-04-03
Lead Sponsor
argenx
Target Recruit Count
24
Registration Number
NCT06203457
Locations
🇭🇺

Debreceni Egyetem, Debrecen, Hungary

🇵🇱

Centrum Medyczne Pratia Poznan, Skorzewo, Poland

🇵🇱

FutureMeds sp zoo, Wroclaw, Poland

and more 8 locations

A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

Recruiting
Conditions
Congenital Myasthenic Syndrome
First Posted Date
2023-10-12
Last Posted Date
2025-05-11
Lead Sponsor
argenx
Target Recruit Count
100
Registration Number
NCT06078553
Locations
🇨🇦

The Ottawa Hospital - Civic Campus, Ottawa, Canada

🇫🇷

CHU Timone, Marseille, France

🇫🇷

Assistance Publique Hopitaux de Paris - Hopital Pitie-Salpetriere, Paris, France

and more 7 locations

A Prospective Longitudinal Study in Adults With Multifocal Motor Neuropathy

Active, not recruiting
Conditions
Multifocal Motor Neuropathy
First Posted Date
2023-08-14
Last Posted Date
2025-02-07
Lead Sponsor
argenx
Target Recruit Count
413
Registration Number
NCT05988073
Locations
🇩🇪

Universitatsklinikum Wurzburg, Wurzburg, Germany

🇮🇹

Azienda Ospedaliero Universitaria Careggi, Firenze, Italy

🇮🇹

Fondazione Serena Onlus - NeMO Brescia, Gussago, Italy

and more 110 locations

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

Phase 3
Conditions
Myositis
Polymyositis
Dermatomyositis
Immune-Mediated Necrotizing Myopathy
Antisynthetase Syndrome
Active Idiopathic Inflammatory Myopathy
Interventions
First Posted Date
2023-08-07
Last Posted Date
2025-05-22
Lead Sponsor
argenx
Target Recruit Count
240
Registration Number
NCT05979441
Locations
🇧🇬

Medical Centre Artmed, Plovdiv, Bulgaria

🇨🇾

Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus

🇨🇿

Revmatologicky Ustav, Praha, Czechia

and more 48 locations

A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod

Phase 1
Completed
Conditions
Renal Impairment
Interventions
Biological: Efgartigimod IV
First Posted Date
2023-07-03
Last Posted Date
2024-06-26
Lead Sponsor
argenx
Target Recruit Count
33
Registration Number
NCT05927415
Locations
🇩🇪

CRS Clinical Research Services Kiel GmbH, Kiel, Germany

🇩🇪

APEX GmbH, Munich, Germany

Open Label Extension of Efgartigimod in Adults with Post-COVID-19 POTS

Phase 2
Terminated
Conditions
Post-COVID Postural Orthostatic Tachycardia Syndrome Postural Orthostatic Tachycardia Syndrome
Interventions
First Posted Date
2023-06-26
Last Posted Date
2024-12-04
Lead Sponsor
argenx
Target Recruit Count
33
Registration Number
NCT05918978
Locations
🇺🇸

North Shore University HealthSystem, Glenview, Illinois, United States

🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

and more 6 locations

ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function

Phase 2
Recruiting
Conditions
Delayed Graft Function
Interventions
Other: Placebo
First Posted Date
2023-06-18
Last Posted Date
2025-04-01
Lead Sponsor
argenx
Target Recruit Count
102
Registration Number
NCT05907096
Locations
🇪🇸

Hospital Universitario Miguel Servet, Zaragoza, Spain

🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

Columbia University, New York, New York, United States

and more 42 locations

A Phase 1 Bioequivalence Study of Efgartigimod PH20 SC Administered Via a Prefilled Syringe Versus a Vial+Syringe Presentation in Healthy Adults

Phase 1
Completed
Conditions
Bioequivalence
Interventions
Biological: efgartigimod PH20 SC as a prefilled syringe presentation
Biological: efgartigimod PH20 SC as a vial + syringe presentation
First Posted Date
2023-04-18
Last Posted Date
2023-10-31
Lead Sponsor
argenx
Target Recruit Count
120
Registration Number
NCT05817435
Locations
🇺🇸

Investigator site 0010209, Tempe, Arizona, United States

🇺🇸

Investigator site 0010208, Lincoln, Nebraska, United States

A Study of the Safety and Effectiveness of Efgartigimod in Patients With Primary Sjögren's Syndrome (pSS)

Phase 2
Completed
Conditions
Primary Sjögren's Syndrome
Interventions
Biological: Placebo
Biological: Efgartigimod
First Posted Date
2023-04-18
Last Posted Date
2024-05-28
Lead Sponsor
argenx
Target Recruit Count
34
Registration Number
NCT05817669
Locations
🇵🇱

ETG Lublin, Lublin, Poland

🇵🇱

Clinical Research Center Spółka z ograniczoną odpowiedzialnością Medic-R Sp.k., Poznan, Poland

🇵🇱

MICS Centrum Medyczne Warszawa, Warszawa, Poland

and more 14 locations

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Primary Membranous Nephropathy (ZL-1103-014)

Phase 2
Terminated
Conditions
Membranous Nephropathy
Interventions
Other: placebo
Biological: efgartigimod IV
First Posted Date
2023-04-13
Last Posted Date
2024-11-22
Lead Sponsor
argenx
Target Recruit Count
8
Registration Number
NCT05810961
Locations
🇨🇳

Fujian Medical University Union Hospital, Fujian, China

🇨🇳

Fuyang People's Hospital, Fuyang, China

🇨🇳

Peking University People's Hospital, Beijing, China

and more 28 locations
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