MedPath

argenx

๐Ÿ‡ง๐Ÿ‡ชBelgium
Ownership
-
Established
2008-01-01
Employees
-
Market Cap
$31.2B
Website
https://www.argenx.com/

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Lupus Nephritis (ZL-1103-013)

Phase 2
Active, not recruiting
Conditions
Lupus Nephritis
Interventions
Biological: efgartigimod IV
Other: Placebo
First Posted Date
2023-04-13
Last Posted Date
2025-02-06
Lead Sponsor
argenx
Target Recruit Count
73
Registration Number
NCT05810948
Locations
๐Ÿ‡จ๐Ÿ‡ณ

Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

๐Ÿ‡จ๐Ÿ‡ณ

Affiliated Hospital of Jining Medical University, Jining, China

๐Ÿ‡จ๐Ÿ‡ณ

Liu Zhou Works Hospital, Liuzhou, China

and more 28 locations

A Phase 3 Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid

Phase 3
Terminated
Conditions
Bullous Pemphigoid
Interventions
Biological: efgartigimod PH20 SC
First Posted Date
2023-01-12
Last Posted Date
2025-04-23
Lead Sponsor
argenx
Target Recruit Count
64
Registration Number
NCT05681481
Locations
๐Ÿ‡จ๐Ÿ‡ณ

The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

๐Ÿ‡จ๐Ÿ‡ณ

Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China

๐Ÿ‡บ๐Ÿ‡ธ

Medical Dermatology Specialists, Phoenix, Arizona, United States

and more 37 locations

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
First Posted Date
2023-01-04
Last Posted Date
2024-08-23
Lead Sponsor
argenx
Target Recruit Count
112
Registration Number
NCT05670704

Efficacy and Safety Study of Efgartigimod in Adults with Post-COVID-19 POTS

Phase 2
Completed
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
Drug: Placebo
First Posted Date
2022-12-01
Last Posted Date
2024-10-03
Lead Sponsor
argenx
Target Recruit Count
53
Registration Number
NCT05633407
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of California, San Diego Sulpizio Cardiovascular Center, La Jolla, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins University, Baltimore, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

Stanford Movement Disorder Center, Palo Alto, California, United States

and more 8 locations

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

Phase 2
Recruiting
Conditions
Active Idiopathic Inflammatory Myopathy
Myositis
Dermatomyositis
Polymyositis
Immune-Mediated Necrotizing Myopathy
Antisynthetase Syndrome
Interventions
First Posted Date
2022-08-31
Last Posted Date
2025-04-03
Lead Sponsor
argenx
Target Recruit Count
240
Registration Number
NCT05523167
Locations
๐Ÿ‡ฏ๐Ÿ‡ต

The University of Tokyo Hospital, Tokyo, Japan

๐Ÿ‡ฉ๐Ÿ‡ช

Universitatsklinikum Ulm - Standort Oberer Eselsberg, Ulm, Germany

๐Ÿ‡ฏ๐Ÿ‡ต

Juntendo University Hospital - Rheumatology, Tokyo, Japan

and more 210 locations

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy

Phase 2
Active, not recruiting
Conditions
Multifocal Motor Neuropathy (MMN)
Interventions
Other: Placebo
First Posted Date
2022-06-06
Last Posted Date
2025-05-13
Lead Sponsor
argenx
Target Recruit Count
51
Registration Number
NCT05405361
Locations
๐Ÿ‡บ๐Ÿ‡ธ

HonorHealth Neurology, Scottsdale, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Austin Neuromuscular Center, Austin, Texas, United States

๐Ÿ‡ฆ๐Ÿ‡น

Medizinische Universitat Wien (Medical University of Vienna), Vienna, Austria

and more 24 locations

Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children with Generalized Myasthenia Gravis

Phase 2
Conditions
Generalized Myasthenia Gravis
Interventions
Biological: Efgartigimod IV or Efgartigimod PH20 SC
First Posted Date
2022-05-16
Last Posted Date
2025-03-03
Lead Sponsor
argenx
Target Recruit Count
12
Registration Number
NCT05374590
Locations
๐Ÿ‡ซ๐Ÿ‡ท

AP-HM- Hรดpital de La Timone, Marseille, France

๐Ÿ‡ง๐Ÿ‡ช

Universitair Ziekenhuis Antwerpen, Edegem, Belgium

๐Ÿ‡บ๐Ÿ‡ธ

Ann and Robert H Lurie Children's Hospital of Chicago - Main Hospital, Chicago, Illinois, United States

and more 7 locations

A Phase 2/3 Study of Efgartigimod PH20 SC in Adult Participants with Bullous Pemphigoid

Phase 2
Completed
Conditions
Bullous Pemphigoid
Interventions
Other: placebo
Biological: efgartigimod PH20 SC
First Posted Date
2022-03-04
Last Posted Date
2024-10-11
Lead Sponsor
argenx
Target Recruit Count
98
Registration Number
NCT05267600
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Investigator site 121 - US0010092, Redwood City, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Investigator site 115 - US0010157, Jackson, Mississippi, United States

๐Ÿ‡บ๐Ÿ‡ธ

Investigator site 34 - US0010182, Houston, Texas, United States

and more 126 locations

A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults with Multifocal Motor Neuropathy

Phase 2
Completed
Conditions
Multifocal Motor Neuropathy
Interventions
Other: Placebo
First Posted Date
2022-02-04
Last Posted Date
2024-10-18
Lead Sponsor
argenx
Target Recruit Count
54
Registration Number
NCT05225675
Locations
๐Ÿ‡บ๐Ÿ‡ธ

HonorHealth Research Institute-Neuroscience Research, Maitland, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

George Washington Medical Faculty Associates, Washington, District of Columbia, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of South Florida Carol and Frank Morsani Center for Advanced Healthcare, Tampa, Florida, United States

and more 36 locations

Immune Response to PNEUMOVAX 23 in Healthy Adults Receiving Efgartigimod IV

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Biological: Efgartigimod
Other: Placebo
Biological: PNEUMOVAX 23
First Posted Date
2021-12-20
Last Posted Date
2022-03-17
Lead Sponsor
argenx
Target Recruit Count
36
Registration Number
NCT05163834
Locations
๐Ÿ‡ณ๐Ÿ‡ฑ

Investigator site 1, Groningen, Netherlands

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