St. Jude Children's Research Hospital

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1962-01-01

Employees: -

Market Cap: -

Website: http://www.stjude.org/

Clinical Trials

Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Not Applicable

Completed

Conditions: Acute Lymphoblastic Leukemia

Interventions: Device: transcranial Direct Current Stimulation (tDCS)
Device: Sham
Other: Cognitive Assessment
Other: Brain Games Stimulation

First Posted Date: 2015-01-12

Last Posted Date: 2023-09-18

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 53

Registration Number: NCT02336282

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Analysis of T Cell and Natural Killer (NK) Cell in Relation to Viral Infections in Pediatric Stem Cell Transplant Patients and Donors

Completed

Conditions: Hematologic Malignancies

First Posted Date: 2014-11-25

Last Posted Date: 2017-07-17

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 35

Registration Number: NCT02301065

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Phase 1

Completed

Conditions: Acute Myeloid Leukemia

Interventions: Drug: Crenolanib
Drug: Sorafenib
Drug: methotrexate, hydrocortisone and cytarabine with leucovorin

First Posted Date: 2014-10-21

Last Posted Date: 2017-10-03

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 10

Registration Number: NCT02270788

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease

Completed

Conditions: Sickle Cell Disease

Interventions: Other: Blood draw
Other: Nasopharyngeal wash

First Posted Date: 2014-10-10

Last Posted Date: 2016-09-19

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 24

Registration Number: NCT02261480

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Phase 2

Terminated

Conditions: Acute Lymphoblastic Leukemia (ALL)
Acute Myeloid Leukemia (AML)
Myeloid Sarcoma
Chronic Myelogenous Leukemia (CML)
Juvenile Myelomonocytic Leukemia (JMML)
Myelodysplastic Syndrome (MDS)
Non-Hodgkin Lymphoma (NHL)

Interventions: Drug: Cyclophosphamide
Drug: Fludarabine
Biological: G-CSF
Biological: Interleukin-2
Drug: Melphalan
Drug: Thiotepa
Drug: Rituximab
Biological: Natural killer cell therapy
Biological: T-cell depleted HPC transplant
Biological: CD45RA-depleted HPC transplant

First Posted Date: 2014-10-08

Last Posted Date: 2017-05-30

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 12

Registration Number: NCT02259348

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer

Active, not recruiting

Conditions: Brain Tumor
Acute Lymphoblastic Leukemia
Hodgkin Lymphoma

First Posted Date: 2014-10-03

Last Posted Date: 2024-08-09

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 1468

Registration Number: NCT02256137

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Theraworx Bath Wipes Versus Standard Bath Wipes in the Reduction of Vancomycin-Resistant Enterococci

Not Applicable

Completed

Conditions: Vancomycin-Resistant Enterococci
Hematopoietic Stem Cell Transplantation

Interventions: Other: Standard bath wipes
Other: Theraworx™ bath wipes

First Posted Date: 2014-09-16

Last Posted Date: 2017-10-06

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 159

Registration Number: NCT02241005

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease

Completed

Conditions: Sickle Cell Disease

Interventions: Other: Evaluation of cognitive and pre-academic skills
Other: Parent questionnaires

First Posted Date: 2014-08-28

Last Posted Date: 2018-09-12

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 84

Registration Number: NCT02227472

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

Phase 1

Completed

Conditions: Acute Myeloid Leukemia (AML)
Acute Lymphoblastic Leukemia (ALL)
Myelodysplastic Syndrome (MDS)
Mixed Phenotype Acute Leukemia (MPAL)

Interventions: Drug: Selinexor
Drug: Fludarabine
Drug: Cytarabine
Drug: methotrexate/hydrocortisone/cytarabine

First Posted Date: 2014-08-08

Last Posted Date: 2020-03-26

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 19

Registration Number: NCT02212561

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
🇺🇸
Cook Children's Medical Center, Fort Worth, Texas, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 3 locations

Incentives to Promote Medication Adherence Among HIV-Infected Youth

Completed

Conditions: HIV

Interventions: Behavioral: Incentive intervention model

First Posted Date: 2014-08-01

Last Posted Date: 2016-06-21

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 25

Registration Number: NCT02206906

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

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