St. Jude Children's Research Hospital

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1962-01-01

Employees: -

Market Cap: -

Website: http://www.stjude.org/

Clinical Trials

Incentives to Promote Medication Adherence Among HIV-Infected Youth

Completed

Conditions: HIV

Interventions: Behavioral: Incentive intervention model

First Posted Date: 2014-08-01

Last Posted Date: 2016-06-21

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 25

Registration Number: NCT02206906

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen

Phase 2

Terminated

Conditions: Hematological Malignancies

Interventions: Drug: Cyclophosphamide
Drug: Thiotepa
Drug: Fludarabine
Drug: Melphalan
Drug: Mesna
Biological: G-CSF
Drug: Mycophenolate mofetil
Drug: Tacrolimus
Drug: Methylprednisolone
Radiation: Total lymphoid irradiation
Biological: Lymphocyte infusions
Device: CliniMACS

First Posted Date: 2014-07-24

Last Posted Date: 2018-02-07

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 24

Registration Number: NCT02199041

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

The Good Patient Study

Completed

Conditions: Solid Tumor
Hematological Malignancies
Brain Tumor

Interventions: Other: Interview

First Posted Date: 2014-07-24

Last Posted Date: 2015-06-04

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 43

Registration Number: NCT02199548

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
🇺🇸
Children's National Health System, Washington, District of Columbia, United States

Feasibility of Generating Pluripotent Stem Cells From Patients With Familial Retinoblastoma

Completed

Conditions: Retinoblastoma

Interventions: Other: Skin Biopsy
Other: Blood Draw

First Posted Date: 2014-07-18

Last Posted Date: 2020-10-23

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 15

Registration Number: NCT02193724

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A Antibody

Completed

Conditions: Ewing Family of Tumors
Osteosarcoma
Melanoma
Neuroblastoma

First Posted Date: 2014-06-10

Last Posted Date: 2020-11-05

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 76

Registration Number: NCT02159443

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Medication Adherence in Youth With Sickle Cell Disease (SCD)

Completed

Conditions: Sickle Cell Disease

Interventions: Behavioral: Demographic Questionnaire
Behavioral: Medical Adherence Measure Questionnaire
Behavioral: Acceptability Questionnaire

First Posted Date: 2014-05-20

Last Posted Date: 2015-05-27

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 36

Registration Number: NCT02143076

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

Phase 1

Completed

Conditions: Neuroblastoma
Lymphoma
High-risk Tumor

Interventions: Biological: CD133+ selected autologous stem cell infusion
Biological: IL-2
Biological: hu14.18K322A
Drug: Melphalan
Drug: Busulfan
Drug: Bendamustine
Biological: GM-CSF
Drug: Etoposide
Drug: Carboplatin
Device: Haploidentical natural killer cell infusion
Drug: Cytarabine
Biological: G-CSF
Device: CliniMACS
Drug: Etoposide phosphate

First Posted Date: 2014-05-06

Last Posted Date: 2017-12-22

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 8

Registration Number: NCT02130869

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

Phase 2

Active, not recruiting

Conditions: Ependymoma

Interventions: Radiation: Irradiation
Procedure: Surgery
Drug: ^1^8F-Fluorodeoxyglucose
Drug: ^1^1C-methionine
Device: Photon therapy
Device: Proton therapy

First Posted Date: 2014-04-29

Last Posted Date: 2024-11-11

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 68

Registration Number: NCT02125786

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Medication Adherence in Human Immunodeficiency Virus (HIV)

Not Applicable

Completed

Conditions: Human Immunodeficiency Virus

Interventions: Other: Demographic Questionnaire
Behavioral: Staff-delivered intervention sessions
Other: Questionnaires

First Posted Date: 2014-04-21

Last Posted Date: 2016-08-02

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 33

Registration Number: NCT02119390

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors

Phase 2

Active, not recruiting

Conditions: Atypical Teratoid Rhabdoid Tumor
Malignant Rhabdoid Tumor

Interventions: Drug: alisertib
Procedure: Surgical resection
Drug: methotrexate
Drug: cisplatin
Drug: carboplatin
Drug: cyclophosphamide
Drug: etoposide
Drug: topotecan
Drug: vincristine
Radiation: Radiation therapy

First Posted Date: 2014-04-15

Last Posted Date: 2024-10-31

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 125

Registration Number: NCT02114229

Locations: 🇺🇸
Children's Healthcare of Atlanta, Atlanta, Georgia, United States
🇺🇸
Texas Children's Hospital, Houston, Texas, United States
🇺🇸
Lucille Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California, United States

and more 6 locations

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