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GENENTECH, INC.

GENENTECH, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

Study to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2016-03-29
Last Posted Date
2017-08-22
Lead Sponsor
Genentech, Inc.
Target Recruit Count
45
Registration Number
NCT02722018
Locations
🇬🇧

Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2016-03-04
Last Posted Date
2020-03-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
50
Registration Number
NCT02699710
Locations
🇬🇧

Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

A Study in Patients With Neovascular Age Related Macular Degeneration or Macular Edema Secondary To Retinal Vein Occlusion to Evaluate Usability of the Ranibizumab (Lucentis®) Prefilled Syringe (PFS)

Phase 3
Completed
Conditions
Macular Edema
Interventions
First Posted Date
2016-03-03
Last Posted Date
2017-09-21
Lead Sponsor
Genentech, Inc.
Target Recruit Count
35
Registration Number
NCT02698566
Locations
🇺🇸

Southeastern Retina Associates, Chattanooga, Tennessee, United States

🇺🇸

Char Eye Ear &Throat Assoc, Charlotte, North Carolina, United States

🇺🇸

Paducah Retinal Center, Paducah, Kentucky, United States

and more 1 locations

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

Phase 3
Completed
Conditions
Multiple Sclerosis, Primary Progressive
Relapsing Multiple Sclerorsis
Interventions
Procedure: Lumbar Puncture
Drug: Methyloprednisolone
Drug: Antihistamine
First Posted Date
2016-02-23
Last Posted Date
2024-06-04
Lead Sponsor
Genentech, Inc.
Target Recruit Count
131
Registration Number
NCT02688985
Locations
🇺🇸

Ohio State University, Columbus, Ohio, United States

🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

University of Massachusetts Medical School, Worcester, Massachusetts, United States

and more 14 locations

A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis

Phase 1
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2016-01-14
Last Posted Date
2020-08-06
Lead Sponsor
Genentech, Inc.
Target Recruit Count
54
Registration Number
NCT02655614
Locations
🇺🇸

Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

🇺🇸

Mayo Clinic Hospital - Florida, Jacksonville, Florida, United States

🇺🇸

Forbes Norris Mda/als Ctr; Research Center, San Francisco, California, United States

and more 7 locations

Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants

Phase 1
Completed
Conditions
Alzheimer's Disease
Interventions
First Posted Date
2015-12-28
Last Posted Date
2019-12-23
Lead Sponsor
Genentech, Inc.
Target Recruit Count
72
Registration Number
NCT02640092
Locations
🇺🇸

Molecular NeuroImaging, New Haven, Connecticut, United States

🇺🇸

Bio Behavioral Health, Toms River, New Jersey, United States

🇺🇸

NeuroCognitive Institute, Mount Arlington, New Jersey, United States

and more 13 locations

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Phase 3
Completed
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
First Posted Date
2015-12-22
Last Posted Date
2020-05-26
Lead Sponsor
Genentech, Inc.
Target Recruit Count
608
Registration Number
NCT02637856
Locations
🇺🇸

The Ohio State University Wexner Medical Center; Department of Neurology, Columbus, Ohio, United States

🇺🇸

Allegheny Neurological Associates, Pittsburgh, Pennsylvania, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 79 locations

A Study to Evaluate Pain, Tolerability, Safety, and Usability of a Single Self-administered Etrolizumab by Auto-injector in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Device: Prefilled Auto-injector (Rotaject)
First Posted Date
2015-12-14
Last Posted Date
2016-11-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
27
Registration Number
NCT02629744

A Study of MHAA4549A as Monotherapy for Acute Uncomplicated Seasonal Influenza A in Otherwise Healthy Adults

Phase 2
Completed
Conditions
Influenza A
Interventions
Drug: Placebo
First Posted Date
2015-12-07
Last Posted Date
2019-01-08
Lead Sponsor
Genentech, Inc.
Target Recruit Count
124
Registration Number
NCT02623322
Locations
🇺🇸

Oceane7 Clinical Research, Miami, Florida, United States

🇺🇸

North Alabama Research Center LLC, Athens, Alabama, United States

🇺🇸

Lalla-Reddy Medical Corporation, Fountain Valley, California, United States

and more 76 locations

Effect of GDC-0810 on the Pharmacokinetics of Pravastatin in Healthy Female Subjects of Non-Childbearing Potential

Phase 1
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2015-12-04
Last Posted Date
2016-11-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
15
Registration Number
NCT02621957
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