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GENENTECH, INC.

GENENTECH, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer

Phase 1
Completed
Conditions
Ovarian Cancer, Pancreatic Cancer
Interventions
First Posted Date
2011-04-15
Last Posted Date
2016-11-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
77
Registration Number
NCT01335958

GDC-0980 in Combination With a Fluoropyrimidine, Oxaliplatin, and Bevacizumab in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Solid Cancers
Interventions
First Posted Date
2011-04-11
Last Posted Date
2016-11-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
41
Registration Number
NCT01332604

A Study of Obinutuzumab (GA101; RO5072759) in Combination With Chemotherapy in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GALTON)

Phase 1
Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2011-02-21
Last Posted Date
2017-02-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
41
Registration Number
NCT01300247

A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer

Phase 1
Terminated
Conditions
Solid Cancers
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2011-02-15
Last Posted Date
2024-07-31
Lead Sponsor
Genentech, Inc.
Target Recruit Count
674
Registration Number
NCT01296555
Locations
🇺🇸

Univ of Chicago, Chicago, Illinois, United States

🇺🇸

Mary Crowley Cancer Rsch Ctr, Dallas, Texas, United States

🇺🇸

Baylor Sammons Cancer Center, Dallas, Texas, United States

and more 28 locations

A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1)

Phase 3
Completed
Conditions
Chronic Idiopathic Urticaria
Interventions
Drug: Placebo
First Posted Date
2011-02-09
Last Posted Date
2013-10-11
Lead Sponsor
Genentech, Inc.
Target Recruit Count
323
Registration Number
NCT01292473

A Study of Escalating Doses of Polatuzumab Vedotin in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and Polatuzumab Vedotin in Combination With Rituximab in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma

Phase 1
Completed
Conditions
Non-Hodgkins Lymphoma
Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2011-02-07
Last Posted Date
2017-06-16
Lead Sponsor
Genentech, Inc.
Target Recruit Count
95
Registration Number
NCT01290549
Locations
🇺🇸

M.D Anderson Cancer Center; Oncology, Houston, Texas, United States

🇺🇸

Florida Cancer Specialists; Sarasota, Sarasota, Florida, United States

🇫🇷

Centre Hospitalier Regional Universitaire de Lille, Lille, France

and more 13 locations

A Study of the Efficacy and Safety of Omalizumab (Xolair) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine (H1) Treatment

Phase 3
Completed
Conditions
Chronic Idiopathic Urticaria
Interventions
Drug: Placebo
First Posted Date
2011-02-01
Last Posted Date
2013-11-27
Lead Sponsor
Genentech, Inc.
Target Recruit Count
319
Registration Number
NCT01287117

A 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-02-01
Last Posted Date
2022-12-13
Lead Sponsor
Genentech, Inc.
Target Recruit Count
46
Registration Number
NCT01287091
Locations
🇺🇸

Investigational Site, Austin, Texas, United States

A Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients With Metastatic Castration-Resistant Prostate Cancer

Phase 1
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2011-01-26
Last Posted Date
2016-10-04
Lead Sponsor
Genentech, Inc.
Target Recruit Count
84
Registration Number
NCT01283373
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