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M.D. ANDERSON CANCER CENTER

🇺🇸United States
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Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors

Phase 1
Recruiting
Conditions
Primary Brain Neoplasm
Interventions
Drug: Hyperpolarized Carbon C 13 Pyruvate
Procedure: Magnetic Resonance Spectroscopic Imaging
First Posted Date
2019-02-05
Last Posted Date
2024-08-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
13
Registration Number
NCT03830151
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Pentoxifylline, Atorvastatin, and Vitamin E in Treating Patients With Erectile Dysfunction After Radiation Therapy for Prostate Cancer

Phase 2
Completed
Conditions
Erectile Dysfunction, CTCAE
Male Erectile Disorder
Prostate Adenocarcinoma
Impotence
Interventions
Drug: Atorvastatin
Drug: Pentoxifylline
Dietary Supplement: Vitamin E Compound
First Posted Date
2019-02-05
Last Posted Date
2023-10-17
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
14
Registration Number
NCT03830164
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer

Phase 2
Active, not recruiting
Conditions
Prostate Adenocarcinoma
Metastatic Prostate Carcinoma
Prostate Carcinoma Metastatic in the Bone
Stage IVB Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8
Interventions
First Posted Date
2019-01-30
Last Posted Date
2024-09-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
60
Registration Number
NCT03821792
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk

Phase 2
Active, not recruiting
Conditions
Resectable Soft Tissue Sarcoma
Stage I Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Stage IA Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Stage IB Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC V8
Interventions
Radiation: Hypofractionated Radiation Therapy
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2019-01-29
Last Posted Date
2024-08-15
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
122
Registration Number
NCT03819985
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

Phase 1
Recruiting
Conditions
Clinical Stage 0 Cutaneous Melanoma AJCC v8
Clinical Stage IIB Cutaneous Melanoma AJCC v8
Clinical Stage IIC Cutaneous Melanoma AJCC v8
Lung Non-Small Cell Carcinoma
Malignant Genitourinary System Neoplasm
Malignant Solid Neoplasm
Pathologic Stage 0 Cutaneous Melanoma AJCC v8
Pathologic Stage I Cutaneous Melanoma AJCC v8
Pathologic Stage IB Cutaneous Melanoma AJCC v8
Pathologic Stage IIA Cutaneous Melanoma AJCC v8
Interventions
Other: Best Practice
Other: Biospecimen Collection
Procedure: Endoscopic Procedure
Procedure: Fecal Microbiota Transplantation
Biological: Infliximab
Other: Laboratory Biomarker Analysis
Drug: Prednisone
Biological: Vedolizumab
First Posted Date
2019-01-28
Last Posted Date
2024-12-06
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
800
Registration Number
NCT03819296
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Effectiveness of an Online Intervention Targeting Cancer-related Fatigue

Not Applicable
Terminated
Conditions
Malignant Neoplasm
Cancer Survivor
Interventions
Other: Internet-Based Intervention
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2019-01-18
Last Posted Date
2020-07-29
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
27
Registration Number
NCT03809130
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Low-Intensity Chemotherapy and Venetoclax in Treating Patients with Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia

Phase 1
Active, not recruiting
Conditions
Recurrent B Acute Lymphoblastic Leukemia
Recurrent T Acute Lymphoblastic Leukemia
Refractory B Acute Lymphoblastic Leukemia
Refractory T Acute Lymphoblastic Leukemia
Interventions
First Posted Date
2019-01-17
Last Posted Date
2025-01-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
50
Registration Number
NCT03808610
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients with HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Phase 2
Active, not recruiting
Conditions
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8
Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma
Oropharyngeal Basaloid Carcinoma
Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8
Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8
Posterior Tongue Squamous Cell Carcinoma
Soft Palate Squamous Cell Carcinoma
Stage III Oropharyngeal Squamous Cell Carcinoma AJCC V7
Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC V7
Interventions
Radiation: Intensity-Modulated Radiation Therapy
Biological: Ipilimumab
Biological: Nivolumab
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2019-01-10
Last Posted Date
2024-10-22
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
37
Registration Number
NCT03799445
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Malignant Solid Neoplasm
Refractory Malignant Solid Neoplasm
Refractory Ovarian Carcinoma
Stage II Pancreatic Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage IIIA Ovarian Cancer AJCC v8
Stage IIIA Prostate Cancer AJCC v8
Stage IIIB Ovarian Cancer AJCC v8
Stage IIIB Prostate Cancer AJCC v8
Stage IIIC Ovarian Cancer AJCC v8
Interventions
Drug: TRPV6 Calcium Channel Inhibitor SOR-C13
First Posted Date
2018-12-24
Last Posted Date
2023-11-18
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
11
Registration Number
NCT03784677
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma

Phase 2
Recruiting
Conditions
Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
Interventions
First Posted Date
2018-12-21
Last Posted Date
2024-11-18
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT03784326
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

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