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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Persistence With Prolia® (Denosumab) in Postmenopausal Women With Osteoporosis

Completed
Conditions
Osteoporosis, Age-Related
First Posted Date
2016-04-08
Last Posted Date
2022-11-29
Lead Sponsor
Amgen
Target Recruit Count
935
Registration Number
NCT02732210
Locations
🇨🇦

Research Site, Quebec, Canada

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))

Phase 3
Completed
Conditions
Subjects With Hyperlipidemia, Dyslipidemia
Interventions
Drug: Placebo
First Posted Date
2016-04-06
Last Posted Date
2022-09-23
Lead Sponsor
Amgen
Target Recruit Count
129
Registration Number
NCT02729025
Locations
🇳🇱

Research Site, Waalwijk, Netherlands

AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia

Phase 1
Completed
Conditions
Relapsed or Refractory Multiple Myeloma
Relapsed or Refractory Acute Myeloid Leukemia
Interventions
First Posted Date
2016-02-05
Last Posted Date
2024-10-29
Lead Sponsor
Amgen
Target Recruit Count
142
Registration Number
NCT02675452
Locations
🇨🇦

University Health Network-Princess Margaret Cancer Centre, Toronto, Ontario, Canada

🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

🇩🇪

Universitaetsklinikum Wuerzburg, Wuerzburg, Germany

and more 21 locations

Safety and Efficacy of Evolocumab in Combination With Statin Therapy in Adults With Diabetes and Hyperlipidemia or Mixed Dyslipidemia

Phase 3
Completed
Conditions
Diabetes, Hyperlipidemia, Mixed Dyslipidemia
Interventions
Biological: Evolocumab
Other: Placebo
First Posted Date
2016-01-25
Last Posted Date
2019-01-11
Lead Sponsor
Amgen
Target Recruit Count
986
Registration Number
NCT02662569
Locations
🇹🇷

Research Site, Kocaeli, Turkey

Observational Study of Apremilast in Patients With Psoriasis in The Netherlands

Completed
Conditions
Psoriasis
First Posted Date
2016-01-12
Last Posted Date
2024-05-13
Lead Sponsor
Amgen
Target Recruit Count
154
Registration Number
NCT02652494
Locations
🇳🇱

Antonius Ziekenhuis Sneek, Sneek, Friesland, Netherlands

🇳🇱

Bravis Ziekenhuis, Bergen op Zoom, North-Brabant, Netherlands

🇳🇱

Amphia, Breda, North-Brabant, Netherlands

and more 9 locations

Study to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Food on the Pharmacokinetics (PK) of the Oral Suspension

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2015-12-29
Last Posted Date
2021-08-05
Lead Sponsor
Amgen
Target Recruit Count
34
Registration Number
NCT02641353
Locations
🇺🇸

Covance Clinical Research Unit Inc, Madison, Wisconsin, United States

Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease

Phase 2
Completed
Conditions
In-situ Small Bowel T-cell Lymphoma
Type II Refractory Celiac Disease (RCD-II)
Interventions
Biological: Placebo
Biological: AMG 714
First Posted Date
2015-12-17
Last Posted Date
2019-12-27
Lead Sponsor
Amgen
Target Recruit Count
28
Registration Number
NCT02633020
Locations
🇪🇸

Clinical Site, Madrid, Spain

A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention

Phase 2
Completed
Conditions
Migraine
Interventions
Drug: Placebo
First Posted Date
2015-12-15
Last Posted Date
2022-10-12
Lead Sponsor
Amgen
Target Recruit Count
475
Registration Number
NCT02630459
Locations
🇯🇵

Research Site, Kai-shi, Yamanashi, Japan

A Study of Otezla® in Patients With Plaque Psoriasis Under Routine Conditions

Completed
Conditions
Psoriasis
First Posted Date
2015-12-10
Last Posted Date
2022-02-08
Lead Sponsor
Amgen
Target Recruit Count
391
Registration Number
NCT02626793
Locations
🇩🇪

Gertraud Krähn-Senftleben, Blaubeuren, Baden-Württemberg, Germany

🇩🇪

Clarissa Allmacher, Hersbruck, Bayern, Germany

🇩🇪

Ildiko Sugar-Bunk, Krumbach, Bayern, Germany

and more 93 locations

Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY232 / KEYNOTE-137)

Phase 1
Completed
Conditions
Carcinoma of the Head and Neck
Interventions
Biological: Pembrolizumab
First Posted Date
2015-12-10
Last Posted Date
2021-09-08
Lead Sponsor
Amgen
Target Recruit Count
36
Registration Number
NCT02626000
Locations
🇬🇧

Research Site, Wirral, United Kingdom

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