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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Efficacy and Safety Study of ABP 215 Compared With Bevacizumab in Patients With Advanced Non-Small Cell Lung Cancer

Phase 3
Completed
Conditions
Non-small Cell Lung Cancer Metastatic
Interventions
First Posted Date
2013-10-21
Last Posted Date
2017-10-19
Lead Sponsor
Amgen
Target Recruit Count
642
Registration Number
NCT01966003
Locations
🇧🇬

Research Site, Ruse, Bulgaria

Single-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines

Phase 1
Completed
Conditions
Migraine
Interventions
Drug: Placebo
First Posted Date
2013-09-30
Last Posted Date
2014-12-09
Lead Sponsor
Amgen
Target Recruit Count
74
Registration Number
NCT01953341
Locations
🇺🇸

Research Site, Salt Lake City, Utah, United States

Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention

Phase 2
Completed
Conditions
Migraine
Interventions
First Posted Date
2013-09-30
Last Posted Date
2022-10-12
Lead Sponsor
Amgen
Target Recruit Count
483
Registration Number
NCT01952574
Locations
🇸🇪

Research Site, Vällingby, Sweden

Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk

Phase 3
Completed
Conditions
Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events
Interventions
Other: Placebo to Evolocumab
Biological: Evolocumab
First Posted Date
2013-09-30
Last Posted Date
2015-12-23
Lead Sponsor
Amgen
Target Recruit Count
409
Registration Number
NCT01953328
Locations
🇯🇵

Research Site, Toshima-ku, Tokyo, Japan

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Phase 1
Completed
Conditions
Solid Tumors
Hematologic Malignancies
Hepatic Impairment
Interventions
First Posted Date
2013-09-24
Last Posted Date
2017-05-02
Lead Sponsor
Amgen
Target Recruit Count
46
Registration Number
NCT01949545
Locations
🇺🇸

Gabrail Cancer Center, Canton, Ohio, United States

🇺🇸

Tennessee Oncology, PLLC, Nashville, Tennessee, United States

🇺🇸

Duke Cancer Institute, Durham, North Carolina, United States

and more 8 locations

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease

Phase 1
Completed
Conditions
Relapsed Multiple Myeloma
End-stage Renal Disease
Interventions
First Posted Date
2013-09-24
Last Posted Date
2017-05-02
Lead Sponsor
Amgen
Target Recruit Count
26
Registration Number
NCT01949532
Locations
🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

🇺🇸

Gabrail Cancer Center, Canton, Ohio, United States

🇺🇸

North Shore-LIJ Health System/Center for Advanced Medicine - North Shore University Hospital, Lake Success, New York, United States

and more 10 locations

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs)

Terminated
Conditions
Urea Cycle Disorder
First Posted Date
2013-09-23
Last Posted Date
2024-07-01
Lead Sponsor
Amgen
Target Recruit Count
203
Registration Number
NCT01948427
Locations
🇺🇸

United BioSource Corporation, Blue Bell, Pennsylvania, United States

Study to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Switch From Cinacalcet to Etelcalcetide

Phase 3
Completed
Conditions
Hyperparathyroidism, Secondary
Interventions
First Posted Date
2013-08-30
Last Posted Date
2018-10-17
Lead Sponsor
Amgen
Target Recruit Count
158
Registration Number
NCT01932970
Locations
🇺🇸

Research Site, Hampton, Virginia, United States

Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to Adalimumab

Phase 4
Terminated
Conditions
Moderate to Severe Rheumatoid Arthritis
Interventions
Biological: Etanercept
First Posted Date
2013-08-23
Last Posted Date
2018-01-30
Lead Sponsor
Amgen
Target Recruit Count
90
Registration Number
NCT01927757
Locations
🇵🇷

Research Site, Caguas, Puerto Rico

A First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma.

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: AMG 282 Matching Placebo
First Posted Date
2013-08-23
Last Posted Date
2016-12-14
Lead Sponsor
Amgen
Target Recruit Count
70
Registration Number
NCT01928368
Locations
🇺🇸

Research Site, Seattle, Washington, United States

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