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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study

Phase 3
Completed
Conditions
Hypercholesterolemia
Interventions
Biological: Evolocumab
Biological: Placebo
Other: Diet Only
First Posted Date
2012-01-25
Last Posted Date
2022-07-22
Lead Sponsor
Amgen
Target Recruit Count
905
Registration Number
NCT01516879
Locations
🇿🇦

Research Site, Bloemfontein, South Africa

AMG 761 in Adults With Asthma

Phase 1
Terminated
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2012-01-23
Last Posted Date
2014-04-21
Lead Sponsor
Amgen
Target Recruit Count
7
Registration Number
NCT01514981
Locations
🇺🇸

Research Site, Miami, Florida, United States

AMG 172 First in Human Study in Patients With Kidney Cancer

Phase 1
Completed
Conditions
Renal Cell Adenocarcinoma
Clear Cell Renal Cell Carcinoma
Clear Cell Renal Carcinoma
Renal Cell Carcinoma
Interventions
First Posted Date
2011-12-23
Last Posted Date
2016-03-25
Lead Sponsor
Amgen
Target Recruit Count
37
Registration Number
NCT01497821
Locations
🇩🇪

Research Site, Heidelberg, Germany

TRINOVA-3: A Study of AMG 386 or AMG 386 Placebo in Combination With Paclitaxel and Carboplatin to Treat Ovarian Cancer

Phase 3
Terminated
Conditions
Fallopian Tube Cancer
Ovarian Cancer
Peritoneal Cancer
Interventions
First Posted Date
2011-12-16
Last Posted Date
2017-02-23
Lead Sponsor
Amgen
Target Recruit Count
1015
Registration Number
NCT01493505
Locations
🇪🇸

Research Site, Madrid, Spain

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 557 in Adults With Psoriasis

Phase 1
Terminated
Conditions
Psoriasis
Interventions
Drug: AMG 557 or PLACEBO
First Posted Date
2011-12-16
Last Posted Date
2013-11-19
Lead Sponsor
Amgen
Target Recruit Count
6
Registration Number
NCT01493518
Locations
🇺🇸

Research Site, Salt Lake City, Utah, United States

Single Ascending Dose Trial in Patients With Type 2 Diabetes

Phase 1
Terminated
Conditions
Diabetes Mellitus
Interventions
First Posted Date
2011-12-15
Last Posted Date
2013-02-15
Lead Sponsor
Amgen
Target Recruit Count
47
Registration Number
NCT01492465
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on Dialysis

Phase 1
Completed
Conditions
Renal Impairment
Interventions
First Posted Date
2011-11-04
Last Posted Date
2016-02-19
Lead Sponsor
Amgen
Target Recruit Count
32
Registration Number
NCT01464931
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Diabetic Nephropathy

Phase 2
Completed
Conditions
Type 2 Diabetes Mellitus
Diabetic Nephropathy
Interventions
Drug: Placebo
Drug: CCX140-B
First Posted Date
2011-10-06
Last Posted Date
2025-02-27
Lead Sponsor
Amgen
Target Recruit Count
332
Registration Number
NCT01447147

Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients

Phase 3
Completed
Conditions
Idiopathic Thrombocytopenic Purpura
Thrombocytopenia
Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Thrombocytopenic Purpura
Immune Thrombocytopenia
Interventions
Drug: Placebo
First Posted Date
2011-09-30
Last Posted Date
2017-02-09
Lead Sponsor
Amgen
Target Recruit Count
62
Registration Number
NCT01444417
Locations
🇨🇦

Research Site, Quebec City, Quebec, Canada

Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia

Completed
Conditions
Colorectal Cancer
Ovarian Cancer
Anemia
Breast Cancer
Cancer
Lung Cancer
Endometrial Cancer
Esophageal Cancer
Gastric Cancer
Solid Tumors
First Posted Date
2011-09-30
Last Posted Date
2017-03-20
Lead Sponsor
Amgen
Target Recruit Count
1262
Registration Number
NCT01444456
Locations
🇷🇴

Research Site, Timisoara, Romania

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