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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Phase 2
Completed
Conditions
Hypercalcemia of Malignancy
Head and Neck Cancer
Metastatic Cancer
Renal Cancer
Endocrine Cancer
Kidney Cancer
Lymphoma
Breast Cancer
Colon Cancer
Parathyroid Neoplasms
Interventions
First Posted Date
2009-05-11
Last Posted Date
2018-10-17
Lead Sponsor
Amgen
Target Recruit Count
33
Registration Number
NCT00896454
Locations
🇵🇱

Research Site, Warszawa, Poland

Romosozumab (AMG 785) in Postmenopausal Women With Low Bone Mineral Density

Phase 2
Completed
Conditions
Low Bone Mineral Density
Postmenopausal Osteoporosis
Interventions
First Posted Date
2009-05-11
Last Posted Date
2022-09-22
Lead Sponsor
Amgen
Target Recruit Count
419
Registration Number
NCT00896532

A High-resolution Peripheral Quantitative Computed Tomography Study in Postmenopausal Women Previously Treated With Denosumab

Phase 3
Completed
Conditions
Low Bone Mass
Low Bone Mineral Density
Postmenopausal Osteoporosis
Osteoporosis
Interventions
Procedure: high-resolution peripheral quantitative computed tomography (HR-pQCT)
Procedure: Dual energy X-ray absorptiometry (DXA)
Biological: Denosumab
Drug: Placebo
First Posted Date
2009-04-30
Last Posted Date
2014-04-02
Lead Sponsor
Amgen
Target Recruit Count
79
Registration Number
NCT00890981

A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab

Phase 2
Completed
Conditions
Low Bone Mineral Density
Osteoporosis
Postmenopausal Osteoporosis
Low Bone Mass
Interventions
First Posted Date
2009-04-24
Last Posted Date
2013-11-15
Lead Sponsor
Amgen
Target Recruit Count
15
Registration Number
NCT00887965

A Study of Extended Carfilzomib Therapy for Patients Previously Enrolled in Carfilzomib Treatment Protocols

Phase 2
Completed
Conditions
Multiple Myeloma
Solid Tumors
Interventions
First Posted Date
2009-04-20
Last Posted Date
2018-05-14
Lead Sponsor
Amgen
Target Recruit Count
101
Registration Number
NCT00884312
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

The Cleveland Clinic Foundation, Cleveland, Ohio, United States

🇺🇸

University of Maryland, Greenebaum Cancer Center, Baltimore, Maryland, United States

and more 20 locations

A Study of Neutropenia and Anemia Management in Patients With Solid Tumors Receiving Myelotoxic Chemotherapy

Completed
Conditions
Ovarian Cancer
Non-Small Cell Lung Cancer
Breast Cancer
Small Cell Lung Cancer
First Posted Date
2009-04-17
Last Posted Date
2017-03-15
Lead Sponsor
Amgen
Target Recruit Count
1370
Registration Number
NCT00883181

Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis

Phase 1
Completed
Conditions
Cystinosis
Interventions
First Posted Date
2009-03-31
Last Posted Date
2024-12-19
Lead Sponsor
Amgen
Target Recruit Count
9
Registration Number
NCT00872729
Locations
🇺🇸

University of California San Diego Medical Center, San Diego, California, United States

A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer

Phase 2
Completed
Conditions
Inoperable Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Interventions
First Posted Date
2009-03-30
Last Posted Date
2016-04-04
Lead Sponsor
Amgen
Target Recruit Count
60
Registration Number
NCT00872014

A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease

Phase 2
Completed
Conditions
Behcet Syndrome
Interventions
First Posted Date
2009-03-20
Last Posted Date
2020-06-19
Lead Sponsor
Amgen
Target Recruit Count
111
Registration Number
NCT00866359
Locations
🇹🇷

Selçuk University, Konya, Turkey

🇺🇸

Mayo Clinic - Rheumatology and Internal Medicine, Jacksonville, Florida, United States

🇺🇸

Cleveland Clinic Foundation, Cleveland, Ohio, United States

and more 4 locations

Effects of Long-term Dosing of AMG 531 on Bone Marrow Morphology

Completed
Conditions
Idiopathic Thrombocytopenic Purpura
Interventions
Other: No Intervention for Observational Study
First Posted Date
2009-03-13
Last Posted Date
2010-07-16
Lead Sponsor
Amgen
Target Recruit Count
10
Registration Number
NCT00861224
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