MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients

Completed

Conditions: Intra-Abdominal Hypertension
Obesity

Interventions: Other: Respiratory mechanics assessment

First Posted Date: 2014-04-07

Last Posted Date: 2015-03-25

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 14

Registration Number: NCT02105220

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)

Completed

Conditions: Pneumonia
Hypoxia
Acute Kidney Injury
Respiratory Failure
Pulmonary Edema
Acute Respiratory Failure Requiring Reintubation

First Posted Date: 2014-04-07

Last Posted Date: 2015-08-21

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 104000

Registration Number: NCT02105298

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Comparison of Stress Reduction Techniques

Not Applicable

Completed

Conditions: Stress

Interventions: Behavioral: Program 1
Behavioral: Program 2

First Posted Date: 2014-03-27

Last Posted Date: 2016-08-02

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 100

Registration Number: NCT02098018

Locations: 🇺🇸
University of Connecticut- Storrs, Storrs, Connecticut, United States
🇺🇸
Massachusettts General Hospital, Boston, Massachusetts, United States

Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

Phase 4

Completed

Conditions: Autism Spectrum Disorder
Attention-deficit/Hyperactivity Disorder

Interventions: Drug: Methylphenidate extended-release liquid formulation

First Posted Date: 2014-03-26

Last Posted Date: 2024-07-01

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 15

Registration Number: NCT02096952

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas

Not Applicable

Completed

Conditions: Diabetes Mellitus Type 1

Interventions: Device: Bionic Pancreas
Device: Insulin pump with or without CGM

First Posted Date: 2014-03-20

Last Posted Date: 2017-11-22

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 48

Registration Number: NCT02092220

Locations: 🇺🇸
Stanford University, Stanford, California, United States
🇺🇸
University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States
🇺🇸
UMass Medical Center, Worcester, Massachusetts, United States

and more 1 locations

Infusion of T-Regulatory Cells in Kidney Transplant Recipients (The ONE Study)

Phase 1

Completed

Conditions: Kidney Failure, Kidney Transplant

First Posted Date: 2014-03-19

Last Posted Date: 2024-03-29

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 4

Registration Number: NCT02091232

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS

Not Applicable

Active, not recruiting

Conditions: Genetics
Metabolism
Type 2 Diabetes

Interventions: Other: Mixed Meal Tolerance Test
Drug: Metformin

First Posted Date: 2014-03-14

Last Posted Date: 2025-05-13

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 1017

Registration Number: NCT02087826

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Ultrasound Method to Measure Fibrosis of the Liver in Children

Not Applicable

Terminated

Conditions: Chronic Liver Disease
HCV Coinfection
Non-Alcoholic Fatty Liver Disease
HBV
Drug-Induced Liver Injury

Interventions: Device: Shear Wave sonoelastography

First Posted Date: 2014-03-13

Last Posted Date: 2017-02-01

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 24

Registration Number: NCT02086708

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT

Phase 1

Terminated

Conditions: Graft Versus Host Disease

Interventions: Drug: LDE225

First Posted Date: 2014-03-13

Last Posted Date: 2018-03-19

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 17

Registration Number: NCT02086513

Locations: 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States

Repeat BCG Vaccinations for the Treatment of Established Type 1 Diabetes

Phase 2

Active, not recruiting

Conditions: Covid19
Diabetes Mellitus, Type One
Diabetes Mellitus, Type I
Autoimmune Diabetes

Interventions: Biological: Bacillus Calmette-Guérin
Biological: Saline injection

First Posted Date: 2014-03-07

Last Posted Date: 2024-05-29

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 150

Registration Number: NCT02081326

Locations: 🇺🇸
Immunobiology Labs CNY 149, Charlestown, Massachusetts, United States

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