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MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States
Ownership
-
Established
1811-01-01
Employees
-
Market Cap
-
Website
http://www.massgeneral.org/international

Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial

Phase 1
Active, not recruiting
Conditions
Amyotrophic Lateral Sclerosis
Mild Cognitive Impairment
Alzheimer Disease
Interventions
First Posted Date
2022-01-12
Last Posted Date
2024-10-04
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
20
Registration Number
NCT05189106
Locations
🇺🇸

Massachusetts General Hospital - ALS Site, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital - AD Site, Charlestown, Massachusetts, United States

Long-Term Effects of Repetitive, Low-Level Blast Exposure on Special Operations Forces Service Members

Completed
Conditions
Traumatic Brain Injury
Blast Injuries
Interventions
Diagnostic Test: 3T Connectome MRI
Diagnostic Test: 7 Tesla MRI
Diagnostic Test: TSPO PET
Diagnostic Test: Tau PET
Diagnostic Test: Cognitive and Behavioral Assessments
Diagnostic Test: Blood Biomarkers
First Posted Date
2022-01-10
Last Posted Date
2023-04-04
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
30
Registration Number
NCT05183087
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Repeat BCG Vaccinations for the Treatment of Pediatric Type 1 Diabetes

Phase 2
Recruiting
Conditions
Diabetes Mellitus, Type 1
Diabetes Type1
Autoimmune Diabetes
Interventions
Biological: Saline Injection
Biological: Bacillus Calmette-Guérin
First Posted Date
2022-01-06
Last Posted Date
2024-11-21
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
150
Registration Number
NCT05180591
Locations
🇺🇸

Immunobiology Labs CNY 149, Charlestown, Massachusetts, United States

Care Planning for a Loved One With Dementia: Knowledge, Preparing for Decisions, and Emotions

Not Applicable
Recruiting
Conditions
Dementia Moderate
Dementia
Dementia, Mild
Dementia Severe
Caregiver Stress Syndrome
Dementia Frontotemporal
Dementia Alzheimers
Caregiver Burnout
Interventions
Other: Video Intervention Arm
First Posted Date
2021-12-21
Last Posted Date
2023-10-19
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
150
Registration Number
NCT05165186
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Building Resiliency in Dyads of Patients With an ANI Admitted to the Neuro-ICU and Their Informal Caregivers

Not Applicable
Recruiting
Conditions
Acute Neurological Injury
Emotional Distress
Interventions
Behavioral: Recovering Together
First Posted Date
2021-12-15
Last Posted Date
2023-12-21
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
388
Registration Number
NCT05157880
Locations
🇺🇸

Massachusetts General Hospital (MGH), Boston, Massachusetts, United States

Screening For BCRL In Targeted Therapy For Breast Cancer

Active, not recruiting
Conditions
Lymphedema Arm
Breast Cancer Metastatic
Breast Cancer Stage
Lymphedema of the Hands
Breast Cancer Lymphedema
Breast Cancer
Lymphedema of Upper Limb
Edema
Lymphedema
Lymphedema of Upper Arm
Interventions
Device: Perometer
Device: SOZO device
First Posted Date
2021-12-03
Last Posted Date
2025-05-22
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
166
Registration Number
NCT05142800
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Care Transition Intervention for Hospitalized Patients with Advanced Cancer

Not Applicable
Recruiting
Conditions
Cancer
Advanced Cancer
Follow-Up Care
Consultation, Remote
Interventions
Other: Usual Care
Other: CONTINUUM Intervention
First Posted Date
2021-12-02
Last Posted Date
2024-12-24
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
286
Registration Number
NCT05142345
Locations
🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Implementing a Digitally-enabled Community Health Worker Intervention for Patients With Heart Failure

Not Applicable
Completed
Conditions
Heart Failure,Congestive
Interventions
Other: Digitally-enabled CHW Care
Behavioral: Usual CHW Care
First Posted Date
2021-11-22
Last Posted Date
2025-04-20
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
56
Registration Number
NCT05130008
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Prostate Cancer Genetic Risk Evaluation and Screening Study

Recruiting
Conditions
BRCA2 Mutation
Prostate Cancer
ATM Gene Mutation
MMR Mutation
BRCA1 Mutation
Prostatic Neoplasm
Lynch Syndrome
Genetic Predisposition to Disease
Interventions
Diagnostic Test: Prostate cancer screening
First Posted Date
2021-11-22
Last Posted Date
2024-10-09
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
400
Registration Number
NCT05129605
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Pressure-enabled Delivery in Radioembolization (TriNav Study)

Not Applicable
Recruiting
Conditions
Liver Cancer
Hepatocellular Carcinoma
Metastatic Colorectal Cancer
Interventions
Device: Standard microcatheter
Device: PEDD device
First Posted Date
2021-11-19
Last Posted Date
2024-11-19
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
20
Registration Number
NCT05128032
Locations
🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

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