DeepMed Research

MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Biomarker Profiling in Individuals at Risk for Prion Disease

Recruiting

Conditions: GSS
Familial Fatal Insomnia
CJD (Creutzfeldt Jakob Disease)
Prion Diseases
FFI

First Posted Date: 2021-11-18

Last Posted Date: 2025-04-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 80

Registration Number: NCT05124392

Locations: 🇺🇸
Alzheimer's Clinical and Translational Research Unit, Charlestown, Massachusetts, United States

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

Not Applicable

Recruiting

Conditions: Subarachnoid Hemorrhage, Aneurysmal

Interventions: Device: gammaCore

First Posted Date: 2021-11-02

Last Posted Date: 2025-05-09

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 25

Registration Number: NCT05103566

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Phase 1

Active, not recruiting

Conditions: Advanced Soft-tissue Sarcoma
Advanced Leiomyosarcoma
Metastatic Soft-tissue Sarcoma
Leiomyosarcoma Metastatic

Interventions: Drug: Lurbinectedin
Drug: Doxorubicin

First Posted Date: 2021-10-29

Last Posted Date: 2024-11-20

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 62

Registration Number: NCT05099666

Locations: 🇺🇸
Mayo Arizona, Phoenix, Arizona, United States
🇺🇸
Mayo Jacksonville, Jacksonville, Florida, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

and more 3 locations

Atezolizumab+Bevacizumab+SBRT in Unresectable HCC

Phase 1

Recruiting

Conditions: Unresectable Hepatocellular Carcinoma

Interventions: Drug: Atezolizumab
Drug: Bevacizumab
Radiation: Stereotactic body radiation therapy (SBRT)

First Posted Date: 2021-10-27

Last Posted Date: 2024-08-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 20

Registration Number: NCT05096715

Locations: 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)

Not Applicable

Active, not recruiting

Conditions: Post-Acute Sequelae of COVID-19
Dysexecutive Syndrome

Interventions: Device: Sham tDCS
Device: Active tDCS

First Posted Date: 2021-10-25

Last Posted Date: 2025-05-08

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 40

Registration Number: NCT05092516

Locations: 🇺🇸
Massachusetts General Hospital, Charlestown, Massachusetts, United States

The SMART ART Study

Not Applicable

Recruiting

Conditions: ART
HIV

Interventions: Other: Smart Lockers (Pele boxes)
Other: Home delivery of ART
Other: Best clinic practices
Other: Best clinic practices + conditional lottery incentives

First Posted Date: 2021-10-22

Last Posted Date: 2024-02-20

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 900

Registration Number: NCT05090150

Locations: 🇿🇦
Human Sciences Research Council Sweetwaters, Sweetwaters, Kwa-zulu Natal, South Africa

The Transitions Project: Efficacy Trial

Not Applicable

Recruiting

Conditions: Lung Cancer

Interventions: Behavioral: Five Psycho-educational Session(s)
Behavioral: One Psycho-educational Session(s)

First Posted Date: 2021-10-21

Last Posted Date: 2022-11-14

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 100

Registration Number: NCT05087251

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Cannabidiol for Reduction of Brain Neuroinflammation

Phase 2

Recruiting

Conditions: Depressive Symptoms
Back Pain

Interventions: Other: Placebo
Drug: CBD

First Posted Date: 2021-10-04

Last Posted Date: 2025-03-30

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 80

Registration Number: NCT05066308

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Mindfulness Oriented Recovery Enhancement in Hospitalized People With Opioid Use Disorder

Not Applicable

Terminated

Conditions: Opioid-use Disorder

Interventions: Behavioral: Mindfulness Oriented Recovery Enhancement Sessions

First Posted Date: 2021-10-04

Last Posted Date: 2024-03-12

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 20

Registration Number: NCT05066321

Locations: 🇺🇸
Division of General Internal Medicine, Boston, Massachusetts, United States

ASPIRED-XT: ASPirin Intervention for the REDuction of Colorectal Cancer Risk -EXTension

Early Phase 1

Active, not recruiting

Conditions: Colorectal Cancer

Interventions: Drug: Aspirin
Other: Placebo

First Posted Date: 2021-09-27

Last Posted Date: 2024-12-04

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 161

Registration Number: NCT05056896

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

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