MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration

Phase 4

Completed

Conditions: Postmenopausal Osteoporosis

Interventions: Drug: Teriparatide
Drug: Denosumab

First Posted Date: 2019-07-19

Last Posted Date: 2023-08-02

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 37

Registration Number: NCT04026256

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Engagement With an Adaptive Mobile Health Smoking Cessation Intervention

Phase 4

Completed

Conditions: Tobacco Use Cessation

Interventions: Behavioral: Brief telephone advice plus tailored text messages
Drug: Mailed nicotine replacement therapy
Behavioral: Proactive telephone coaching

First Posted Date: 2019-07-16

Last Posted Date: 2022-03-10

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 35

Registration Number: NCT04020718

Locations: 🇺🇸
Massacusetts General Hospital, Boston, Massachusetts, United States

Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients

Phase 2

Recruiting

Conditions: Cardiovascular Diseases
Oxidative Stress
Endothelial Dysfunction

Interventions: Drug: Nitrogen Gas for Inhalation
Other: Blood withdrawal
Drug: Nitric Oxide

First Posted Date: 2019-07-16

Last Posted Date: 2022-11-10

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 100

Registration Number: NCT04022161

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇬🇧
MP 825 Southampton General Hospita, Southampton, Hampshire, United Kingdom

Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS

Phase 4

Recruiting

Conditions: PANDAS
Anxiety Disorder
Obsessive-Compulsive Disorder
Autoimmune Diseases

Interventions: Other: Placebo
Drug: Naproxen Sodium

First Posted Date: 2019-07-11

Last Posted Date: 2023-03-27

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 70

Registration Number: NCT04015596

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Modulation Effects of Baduanjin Exercise on Subjective Cognitive Decline

Not Applicable

Completed

Conditions: Cognitive Decline

Interventions: Other: Baduanjin Exercise
Other: Cognitive Fitness Program

First Posted Date: 2019-07-05

Last Posted Date: 2025-06-03

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 124

Registration Number: NCT04009382

Locations: 🇺🇸
Massachusetts General Hospital, Charlestown, Massachusetts, United States

Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

Phase 2

Recruiting

Conditions: Breast Cancer

Interventions: Drug: Talazoparib

First Posted Date: 2019-06-19

Last Posted Date: 2024-07-23

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 30

Registration Number: NCT03990896

Locations: 🇺🇸
Emory University Winship Cancer Institute, Atlanta, Georgia, United States
🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States

and more 4 locations

Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention

Not Applicable

Completed

Conditions: Depression
Anxiety

Interventions: Behavioral: Waitlist Control

First Posted Date: 2019-06-19

Last Posted Date: 2023-07-25

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 60

Registration Number: NCT03992027

Locations: 🇺🇸
Stanford University, Palo Alto, California, United States
🇺🇸
University at Buffalo, Buffalo, New York, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

and more 1 locations

mFOCUS (Multilevel FOllow-up of Cancer Screening)

Not Applicable

Completed

Conditions: Cancer

Interventions: Other: mFOCUS

First Posted Date: 2019-06-07

Last Posted Date: 2024-05-10

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 11980

Registration Number: NCT03979495

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Dartmouth Hitchcock, Hanover, New Hampshire, United States

Multimodal Mobile Intervention Application (App) to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors

Not Applicable

Completed

Conditions: Other Cancer

Interventions: Behavioral: Mobile App + enhanced standard care
Other: Enhanced Standard Care

First Posted Date: 2019-05-30

Last Posted Date: 2025-02-04

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 60

Registration Number: NCT03967379

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Promoting Informed Decisions About Cancer Screening in Older Adults

Not Applicable

Completed

Conditions: Colorectal Cancer Screening

Interventions: Behavioral: Notification
Behavioral: Training

First Posted Date: 2019-05-22

Last Posted Date: 2025-01-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 536

Registration Number: NCT03959696

Locations: 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸
Maine Medical Center, Portland, Maine, United States
🇺🇸
North Shore Medical Center, Danvers, Massachusetts, United States

and more 2 locations

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