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MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy

Not Applicable

Completed

Conditions: Lung Cancer

Interventions: Procedure: Cryoablation
Procedure: Biopsy

First Posted Date: 2017-09-25

Last Posted Date: 2024-03-18

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 30

Registration Number: NCT03290677

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

A Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung Cancer

Phase 2

Terminated

Conditions: Lung Cancer

Interventions: Drug: EGF816
Drug: Gefitinib

First Posted Date: 2017-09-25

Last Posted Date: 2025-06-10

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 11

Registration Number: NCT03292133

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke

Phase 1

Terminated

Conditions: Stroke
Upper Extremity Paresis

Interventions: Device: Inactive RAVANS concurrent with arm motor training
Device: Active RAVANS concurrent with arm motor training

First Posted Date: 2017-09-25

Last Posted Date: 2021-09-21

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 6

Registration Number: NCT03292159

Locations: 🇺🇸
Spaulding Rehabilitation Hospital, Boston, Massachusetts, United States

tACS for Amyloid-β Reduction in Alzheimer's Disease

Not Applicable

Completed

Conditions: Alzheimer Disease

Interventions: Device: Transcranial Alternating Current Stimulation (tACS)

First Posted Date: 2017-09-21

Last Posted Date: 2022-08-22

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 17

Registration Number: NCT03290326

Locations: 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer

Phase 2

Recruiting

Conditions: Breast Cancer

Interventions: Drug: Ribociclib
Other: Endocrine therapy

First Posted Date: 2017-09-18

Last Posted Date: 2024-04-01

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 120

Registration Number: NCT03285412

Locations: 🇺🇸
Mass General/North Shore Cancer Center, Danvers, Massachusetts, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Ruxolitinib + Allogeneic Stem Cell Transplantation in AML

Phase 2

Recruiting

Conditions: Acute Myeloid Leukemia
Acute Myeloid Leukemia in Remission
Allogeneic Stem Cell Transplantation

Interventions: Drug: Ruxolitinib

First Posted Date: 2017-09-18

Last Posted Date: 2024-03-07

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 64

Registration Number: NCT03286530

Locations: 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
The Ohio State University, Columbus, Ohio, United States

and more 3 locations

Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy

Not Applicable

Recruiting

Conditions: Brain Tumor

Interventions: Radiation: Proton Radiation

First Posted Date: 2017-09-18

Last Posted Date: 2024-03-26

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 100

Registration Number: NCT03286335

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation

Not Applicable

Recruiting

Conditions: Brain Tumor

Interventions: Radiation: Proton Beam

First Posted Date: 2017-09-13

Last Posted Date: 2021-01-05

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 20

Registration Number: NCT03281889

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States

A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

Phase 1

Active, not recruiting

Conditions: GastroEsophageal Cancer

Interventions: Drug: Irinotecan
Drug: Oxaliplatin
Drug: Leucovorin
Drug: 5-Fluorouracil
Drug: Paclitaxel
Radiation: Radiation Therapy
Drug: Carboplatin

First Posted Date: 2017-09-12

Last Posted Date: 2022-10-05

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 25

Registration Number: NCT03279237

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Phase II Trial of Pembrolizumab in Recurrent or Residual High Grade Meningioma

Phase 2

Active, not recruiting

Conditions: High Grade Meningioma

Interventions: Drug: Pembrolizumab

First Posted Date: 2017-09-12

Last Posted Date: 2024-04-16

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 26

Registration Number: NCT03279692

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States

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