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University of Oxford

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1096-01-01

Employees: 10K

Market Cap: -

Website: http://www.ox.ac.uk

Clinical Trials

A Study to Assess the Safety and Immunogenicity of a Malaria Vaccine Candidate, R21, Administered With AS01B

Phase 1

Completed

Conditions: Malaria

Interventions: Biological: R21 with ASO1B

First Posted Date: 2015-11-09

Last Posted Date: 2017-06-20

Lead Sponsor: University of Oxford

Target Recruit Count: 20

Registration Number: NCT02600975

Locations: 🇬🇧
CCVTM, University of Oxford, Oxford, United Kingdom
🇬🇧
NIHR Wellcome Trust Clinical Research Facility, Southampton, United Kingdom

Individualised Informal Caregiver Training for Palliative Care at Home

Not Applicable

Terminated

Conditions: Palliative Care

Interventions: Behavioral: Caregiver training

First Posted Date: 2015-10-29

Last Posted Date: 2016-06-03

Lead Sponsor: University of Oxford

Target Recruit Count: 14

Registration Number: NCT02591693

Locations: 🇬🇧
Sir Michael Sobell House Hospice, Oxford, Oxfordshire, United Kingdom

Studying Movement Control in Parkinson's Disease Using Closed Loop Deep Brain Stimulation

Not Applicable

Completed

Conditions: Parkinson Disease

Interventions: Procedure: Deep Brain Stimulation applied through custom built external stimulator (Little et al., 2013, 2015)
Procedure: Deep Brain Stimulation off
Procedure: closed-loop Deep Brain Stimulation applied through custom built external stimulator (Little et al., 2013, 2015)
Device: local field potentials and electroencephalography recordings

First Posted Date: 2015-10-23

Last Posted Date: 2021-05-04

Lead Sponsor: University of Oxford

Target Recruit Count: 30

Registration Number: NCT02585154

Locations: 🇬🇧
University College London Hospitals NHS Trust, London, United Kingdom
🇬🇧
Oxford University Hospitals NHS Trust, Oxford, United Kingdom

Aetiology of TemporaL Arteritis Study

Withdrawn

Conditions: Temporal Arteritis

First Posted Date: 2015-10-22

Last Posted Date: 2022-08-15

Lead Sponsor: University of Oxford

Registration Number: NCT02584517

A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, Administered With and Without Matrix-M1

Phase 1

Completed

Conditions: Malaria

Interventions: Biological: R21
Biological: Matrix-M1

First Posted Date: 2015-10-08

Last Posted Date: 2019-11-12

Lead Sponsor: University of Oxford

Target Recruit Count: 31

Registration Number: NCT02572388

Locations: 🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, Oxfordshire, United Kingdom
🇬🇧
NIHR Wellcome Trust Clinical Research Facility, Hammersmith Hospital, London, United Kingdom

Pharmacokinetic and Mosquito-Lethal Effects of Ivermectin (IVM), Primaquine (PQ), Dihydroartemisinin-Piperaquine (DHA-PQP) and Albendazole (ABZ) in Healthy Subjects

Phase 1

Completed

Conditions: Drug Combination
Pharmacokinetics
Healthy

Interventions: Drug: IVM, IVM and PQ, IVM and DHA-PQP, IVM and DHA-PQP and PQ
Drug: PQ and DHA-PQP and PQ
Drug: DHA-PQP

First Posted Date: 2015-10-05

Last Posted Date: 2017-05-31

Lead Sponsor: University of Oxford

Target Recruit Count: 16

Registration Number: NCT02568098

Locations: 🇹🇭
Faculty of Tropical Medicine, Bangkok, Thailand

A Study to Assess the Safety of Hep C Vaccine Candidates in HIV Seropositive Individuals

Phase 1

Completed

Conditions: Hepatitis C Infection

Interventions: Biological: AdCh3NSmut1
Biological: MVA-NSmut

First Posted Date: 2015-10-05

Last Posted Date: 2018-10-11

Lead Sponsor: University of Oxford

Target Recruit Count: 20

Registration Number: NCT02568332

Locations: 🇨🇭
Kantonsspital St. Gallen, St. Gallen, Switzerland
🇮🇪
St James's Hospital, Dublin, Ireland

Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma

Phase 2

Completed

Conditions: Relapsed Ewing Sarcoma
Refractory Ewing Sarcoma

Interventions: Drug: Linsitinib

First Posted Date: 2015-09-11

Last Posted Date: 2019-06-03

Lead Sponsor: University of Oxford

Target Recruit Count: 16

Registration Number: NCT02546544

Locations: 🇳🇱
Department of Clinical Oncology, Leiden University Medical Center, Leiden, Postzone K1-P, Netherlands
🇮🇹
Istituti Ortopedici Rizzoli, Bologna, Italy
🇫🇷
Universitè Lyon 1 Claude Bernard, Lyon, France

and more 2 locations

MVA85A Aerosol vs Intramuscular Vaccination in Adults With Latent Mycobacterium Tuberculosis (M. tb) Infection

Phase 1

Terminated

Conditions: Tuberculosis

Interventions: Biological: Aerosol inhaled MVA85A
Biological: Intramuscular MVA85A
Biological: Intramuscular Saline placebo
Biological: Aerosol inhaled Saline placebo

First Posted Date: 2015-08-25

Last Posted Date: 2020-08-31

Lead Sponsor: University of Oxford

Target Recruit Count: 2

Registration Number: NCT02532036

Locations: 🇬🇧
NIHR/Wellcome Trust King's Clinical Research Facility, London, United Kingdom
🇬🇧
Royal Free Hospital NHS Foundation Trust, London, United Kingdom
🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine (CCVTM), Churchill Hospital, Oxford, Oxfordshire, United Kingdom

and more 2 locations

A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313

Phase 1

Completed

Conditions: Malaria

Interventions: Biological: ChAd63 Pfs25-IMX313
Biological: MVA Pfs25-IMX313

First Posted Date: 2015-08-25

Last Posted Date: 2017-07-17

Lead Sponsor: University of Oxford

Target Recruit Count: 26

Registration Number: NCT02532049

Locations: 🇬🇧
CCVTM, University of Oxford, Churchill Hospital, Oxford, United Kingdom
🇬🇧
NIHR Wellcome Trust Clinical Research Facility, Southampton, United Kingdom

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