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Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated logo
🇺🇸United States
Ownership
Public
Established
1989-01-01
Employees
5.4K
Market Cap
$123.9B
Website
http://www.vrtx.com

Study of VX-770 in Subjects With Moderate Hepatic Impairment and in Matched Healthy Subjects

Phase 1
Completed
Conditions
In Development for Cystic Fibrosis
Interventions
First Posted Date
2010-09-23
Last Posted Date
2011-01-12
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
24
Registration Number
NCT01208285

Study of the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis and the G551D Mutation

Phase 2
Completed
Conditions
Cystic Fibrosis
Interventions
Drug: Placebo
First Posted Date
2010-07-13
Last Posted Date
2014-07-31
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
13
Registration Number
NCT01161537

Study of VX-770 on Desipramine

Phase 1
Completed
Conditions
In Development for Cystic Fibrosis
Interventions
First Posted Date
2010-06-30
Last Posted Date
2010-12-09
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
24
Registration Number
NCT01153542
Locations
🇺🇸

Covance CRU, Inc., Daytona Beach, Florida, United States

Study of VX-985 in Subjects With Chronic Hepatitis C

Phase 1
Completed
Conditions
Chronic Hepatitis C
Interventions
Drug: VX-985 or matching placebo
First Posted Date
2010-06-16
Last Posted Date
2011-03-09
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
21
Registration Number
NCT01144936
Locations
🇺🇸

Kansas, Overland Park, Kansas, United States

🇺🇸

Maryland, Baltimore, Maryland, United States

🇺🇸

Washington, Tacoma, Washington, United States

Rollover Study of VX-770 in Cystic Fibrosis Subjects

Phase 3
Completed
Conditions
Cystic Fibrosis
Interventions
First Posted Date
2010-05-05
Last Posted Date
2015-07-07
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
192
Registration Number
NCT01117012

A Safety and Efficacy Study of the Combination of VX-222 and Telaprevir in Treatment-Naïve Subjects With Genotype 1 Chronic Hepatitis C Virus Infection

Phase 2
Terminated
Conditions
Chronic Hepatitis C Virus Infection
Interventions
Biological: peginterferon-alfa-2a
First Posted Date
2010-03-04
Last Posted Date
2020-09-30
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
152
Registration Number
NCT01080222

Study of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770

Phase 1
Completed
Conditions
Cystic Fibrosis
Interventions
First Posted Date
2010-02-02
Last Posted Date
2010-04-16
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
24
Registration Number
NCT01060566
Locations
🇺🇸

Covan CRU, Inc., Daytona Beach, Florida, United States

A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
First Posted Date
2010-01-20
Last Posted Date
2012-12-13
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
206
Registration Number
NCT01052194

Study of VX-765 in Subjects With Treatment-resistant Partial Epilepsy

Phase 2
Completed
Conditions
Partial Epilepsy
Interventions
First Posted Date
2010-01-13
Last Posted Date
2014-01-27
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
60
Registration Number
NCT01048255
Locations
🇺🇸

Arkansas, Little Rock, Arkansas, United States

🇺🇸

California, Newport Beach, California, United States

🇺🇸

Florida, Sarasota, Florida, United States

and more 7 locations

A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults

Phase 1
Completed
Conditions
Hepatitis C
Interventions
First Posted Date
2009-12-23
Last Posted Date
2010-04-08
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
20
Registration Number
NCT01038167
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