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Biogen

Biogen logo
🇺🇸United States
Ownership
Private
Established
1978-01-01
Employees
7.5K
Market Cap
$29.6B
Website
https://www.biogen.com
Introduction

Biogen, Inc. is a biopharmaceutical company, which engages in discovering, developing, and delivering therapies for neurological and neurodegenerative diseases. Its products include TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI and FAMPYRA for the treatment of MS, SPINRAZA for the treatment of SMA, ADUHELM for the treatment of Alzheimer's disease, and FUMADERM for the treatment of severe plaque psoriasis. The company was founded by Charles Weissmann, Heinz Schaller, Kenneth Murray, Walter Gilbert, and Phillip Allen Sharp in 1978 and is headquartered in Cambridge, MA.

A Study of End of Dose Phenomena in Subcutaneous Natalizumab Treated Multiple Sclerosis (MS) Participants

Active, not recruiting
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2023-01-27
Last Posted Date
2024-06-14
Lead Sponsor
Biogen
Target Recruit Count
34
Registration Number
NCT05701423
Locations
🇩🇪

Klinik für Neurologie, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

A Study to Assess Pregnancy Outcomes in Women Exposed to Diroximel Fumarate

First Posted Date
2023-01-18
Last Posted Date
2025-01-30
Lead Sponsor
Biogen
Target Recruit Count
1178
Registration Number
NCT05688436
Locations
🇺🇸

OptumInsight, Eden Prairie, Minnesota, United States

A Study of Dimethyl Fumarate (DMF) in Relapsing Forms of Multiple Sclerosis (RMS) Participants in China

Phase 4
Completed
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2022-12-20
Last Posted Date
2025-05-16
Lead Sponsor
Biogen
Target Recruit Count
60
Registration Number
NCT05658484
Locations
🇨🇳

Beijing Hospital, Beijing, China

🇨🇳

Xiangya Hospital Central South University, Changsha, China

🇨🇳

West China Hospital of Sichuan University, Chengdu City, China

and more 12 locations

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

Recruiting
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2022-12-20
Last Posted Date
2024-06-24
Lead Sponsor
Biogen
Target Recruit Count
908
Registration Number
NCT05658497
Locations
🇺🇸

IQVIA US Office, Durham, North Carolina, United States

🇩🇪

Katholisches Klinikum Bochum, Bochum, Nordrhein Westfalen, Germany

🇮🇪

St Vincent's University Hospital, Dublin, Ireland

and more 2 locations

Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD)

Phase 1
Completed
Conditions
Major Depressive Disorder
Interventions
First Posted Date
2022-12-19
Last Posted Date
2025-03-26
Lead Sponsor
Biogen
Target Recruit Count
19
Registration Number
NCT05655507
Locations
🇺🇸

Sage Investigational Site, Cincinnati, Ohio, United States

Adult Spinal Muscular Atrophy (SMA) China Registry

Active, not recruiting
Conditions
Muscular Atrophy, Spinal
First Posted Date
2022-11-16
Last Posted Date
2024-06-21
Lead Sponsor
Biogen
Target Recruit Count
200
Registration Number
NCT05618379
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, Beijing, China

🇨🇳

The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

🇨🇳

The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

and more 9 locations

A Study to Learn About the Safety of Salanersen (BIIB115) Injections and How Salanersen is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec

Phase 1
Active, not recruiting
Conditions
Healthy Volunteer
Muscular Atrophy, Spinal
Interventions
Drug: Salanersen-Matching Placebo
First Posted Date
2022-10-12
Last Posted Date
2025-05-14
Lead Sponsor
Biogen
Target Recruit Count
62
Registration Number
NCT05575011
Locations
🇧🇪

Universitair Ziekenhuis Gent, Gent, Belgium

🇨🇦

Children's Hospital of Eastern Ontario, Ontario, Canada

🇫🇷

Hôpital Armand Trousseau, Paris, France

and more 14 locations

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus (AMETHYST)

Phase 2
Recruiting
Conditions
Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus
Interventions
Drug: Placebo
First Posted Date
2022-09-08
Last Posted Date
2025-06-19
Lead Sponsor
Biogen
Target Recruit Count
474
Registration Number
NCT05531565
Locations
🇺🇸

Pinnacle Research Group, LLC, Anniston, Alabama, United States

🇺🇸

UAB Center for Women's Reproductive Health, Birmingham, Alabama, United States

🇺🇸

Arizona Arthritis & Rheumatology Research, PLLC, Phoenix, Arizona, United States

and more 252 locations

A Study to Investigate the Radiological Onset of Action After Treatment Initiation With Subcutaneous (SC) Natalizumab in Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)

Phase 4
Terminated
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
First Posted Date
2022-09-08
Last Posted Date
2024-06-21
Lead Sponsor
Biogen
Target Recruit Count
1
Registration Number
NCT05532163
Locations
🇩🇪

Neurologische Praxis Dr. med. Boris-Alexander Kallmann, Bamberg, Germany

🇩🇪

Neurologische Studiengesellschaft Bonn GbR, Bonn, Germany

A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale

Phase 3
Terminated
Conditions
Parkinson Disease
Interventions
Drug: BIIB122-Matching Placebo
First Posted Date
2022-06-14
Last Posted Date
2024-06-26
Lead Sponsor
Biogen
Target Recruit Count
7
Registration Number
NCT05418673
Locations
🇺🇸

University of California San Francisco (UCSF), San Francisco, California, United States

🇺🇸

University of Colorado, Aurora, Colorado, United States

🇺🇸

Rocky Mountain Movement Disorders Center, PC, Englewood, Colorado, United States

and more 24 locations
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