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MAYO CLINIC

MAYO CLINIC logo
🇺🇸United States
Ownership
Subsidiary
Established
1889-01-01
Employees
10K
Market Cap
-
Website
http://www.mayoclinic.org

A Study to Assess the Role of Fenofibrate in Preventing Ischemic Cholangiopathy After Liver Transplantation

Phase 2
Recruiting
Conditions
Liver Transplant
Interventions
First Posted Date
2022-08-24
Last Posted Date
2024-07-03
Lead Sponsor
Mayo Clinic
Target Recruit Count
148
Registration Number
NCT05514119
Locations
🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

MIBG in Aging and Neurologic Disorders

Phase 4
Conditions
Dementia
Parkinsonism
REM Sleep Behavior Disorder
Lewy Body Disease
Mild Cognitive Impairment
Interventions
Drug: meta-iodobenzylguanidine (MIBG) (123I)
Diagnostic Test: 123I-MIBG scintigraphy
First Posted Date
2022-08-24
Last Posted Date
2024-06-14
Lead Sponsor
Mayo Clinic
Target Recruit Count
50
Registration Number
NCT05514106
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation

Not Applicable
Withdrawn
Conditions
Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma
Head and Neck Carcinoma
Stage III Hypopharyngeal Carcinoma AJCC v8
Stage IV Lip and Oral Cavity Cancer AJCC v8
Stage II Lip and Oral Cavity Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage II Laryngeal Cancer AJCC v8
Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma
Clinical Stage IV HPV-Mediated (p16-pos)Oropharyngeal Carcinoma
Interventions
Other: Consensus Auditory-Perceptual Evaluation of Voice
Other: Best Practice
Procedure: Diagnostic Imaging
Other: Lymphedema Management
Procedure: Modified Barium Swallow
Procedure: Nasopharyngeal Laryngoscopy
Device: Pneumatic Compression Therapy
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Other: Voice Handicap Index-10
First Posted Date
2022-08-23
Last Posted Date
2023-01-06
Lead Sponsor
Mayo Clinic
Registration Number
NCT05512767

TTI-622 and TTI-621 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Phase 2
Recruiting
Conditions
Recurrent ALK Positive Large B-Cell Lymphoma
Recurrent B-Cell Non-Hodgkin Lymphoma
Recurrent Diffuse Large B-Cell Lymphoma Associated with Chronic Inflammation
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Recurrent EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Recurrent Grade 3b Follicular Lymphoma
Recurrent High Grade B-Cell Lymphoma
Recurrent High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Drug: Ontorpacept
Biological: Pembrolizumab
Procedure: Positron Emission Tomography
Drug: Maplirpacept
Procedure: Biopsy
First Posted Date
2022-08-19
Last Posted Date
2023-10-12
Lead Sponsor
Mayo Clinic
Target Recruit Count
62
Registration Number
NCT05507541
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Recruiting
Conditions
Breast Carcinoma
Cardiotoxicity
Interventions
Procedure: Biospecimen Collection
Other: Electronic Medical Record
First Posted Date
2022-08-19
Last Posted Date
2024-08-02
Lead Sponsor
Mayo Clinic
Target Recruit Count
300
Registration Number
NCT05507879
Locations
🇺🇸

Mayo Clinic in Florida, Jacksonville, Florida, United States

🇺🇸

University of Florida, Gainesville, Florida, United States

Effects of Energy Drinks on Sleep and Cardiovascular Health

Not Applicable
Completed
Conditions
Healthy
Caffeine
Interventions
Other: Energy Drink
Other: Placebo Drink
First Posted Date
2022-08-17
Last Posted Date
2024-11-15
Lead Sponsor
Mayo Clinic
Target Recruit Count
54
Registration Number
NCT05503732
Locations
🇺🇸

Mayo Clinic Rochester, Rochester, Minnesota, United States

Measuring Symptom Relief After Radiofrequency Ablation of the Thyroid

Conditions
Thyroid
First Posted Date
2022-08-15
Last Posted Date
2023-09-11
Lead Sponsor
Mayo Clinic
Target Recruit Count
300
Registration Number
NCT05501041
Locations
🇺🇸

Mayo Clinic Rochester, Rochester, Minnesota, United States

The Effects of Synaquell on Brain Function of Ice Hockey Players

Not Applicable
Completed
Conditions
Healthy
Interventions
Dietary Supplement: Synaquell
Dietary Supplement: Placebo
First Posted Date
2022-08-12
Last Posted Date
2024-01-09
Lead Sponsor
Mayo Clinic
Target Recruit Count
81
Registration Number
NCT05498818
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

A Study to Evaluate Caregiver Connections Via Technology for Patients With Alzheimer's and Other Types of Dementia

Not Applicable
Withdrawn
Conditions
Frontotemporal Dementia
Dementia
Alzheimer Dementia
Parkinson Disease Dementia
Caregiver Stress
Lewy Body Dementia
Interventions
Behavioral: Algorithm
Behavioral: Random Match
First Posted Date
2022-08-11
Last Posted Date
2022-11-17
Lead Sponsor
Mayo Clinic
Registration Number
NCT05497817

Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial

Phase 2
Recruiting
Conditions
ISS Stage III Plasma Cell Myeloma
Multiple Myeloma
Interventions
Procedure: Bone Marrow Aspiration and Biopsy
Drug: Carfilzomib
Procedure: Computed Tomography
Biological: Daratumumab
Drug: Dexamethasone
Drug: Lenalidomide
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
Procedure: Multigated Acquisition Scan
First Posted Date
2022-08-11
Last Posted Date
2024-12-24
Lead Sponsor
Mayo Clinic
Target Recruit Count
75
Registration Number
NCT05497804
Locations
🇺🇸

Mayo Clinic in Arizona, Scottsdale, Arizona, United States

🇺🇸

Mayo Clinic, Jacksonville, Florida, United States

🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

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