MAYO CLINIC

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary

Established: 1889-01-01

Employees: 10K

Market Cap: -

Website: http://www.mayoclinic.org

Clinical Trials

A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

Phase 4

Recruiting

Conditions: Pain Control

Interventions: Drug: Hydromorphone 2.5 mcg/kg
Drug: Hydromorphone 2.75 mcg/kg
Drug: Hydromorphone 3.5 mcg/kg
Drug: Hydromorphone 4 mcg/kg
Drug: Hydromorphone 4.5 mcg/kg
Drug: Hydromorphone 5 mcg/kg
Drug: Hydromorphone 3 mcg/kg
Drug: Hydromorphone 3.25 mcg/kg

First Posted Date: 2022-09-23

Last Posted Date: 2025-01-07

Lead Sponsor: Mayo Clinic

Target Recruit Count: 40

Registration Number: NCT05552443

Locations: 🇺🇸
Mayo Clinic Rochester, Rochester, Minnesota, United States

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Phase 1

Recruiting

Conditions: Recurrent Chronic Myelomonocytic Leukemia
Refractory Chronic Myelomonocytic Leukemia
Recurrent Atypical Chronic Myeloid Leukemia
Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified
Recurrent Myelodysplastic/Myeloproliferative Neoplasm
Refractory Myelodysplastic/Myeloproliferative Neoplasm

Interventions: Procedure: Biospecimen Collection
Procedure: Bone Marrow Aspiration and Biopsy
Drug: Onvansertib
Procedure: Ultrasound Imaging

First Posted Date: 2022-09-22

Last Posted Date: 2025-01-06

Lead Sponsor: Mayo Clinic

Target Recruit Count: 25

Registration Number: NCT05549661

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

68Ga-PSMA-11 PET/CT Screening Prior to 177Lu-PSMA-617 Therapy for Patients With Metastatic Castrate Resistant Prostate Cancer

Phase 3

Completed

Conditions: Metastatic Prostate Carcinoma
Stage IVB Prostate Cancer AJCC v8
Castration-Resistant Prostate Carcinoma

Interventions: Procedure: Computed Tomography
Drug: Gallium Ga 68 Gozetotide
Procedure: Positron Emission Tomography

First Posted Date: 2022-09-21

Last Posted Date: 2024-01-17

Lead Sponsor: Mayo Clinic

Target Recruit Count: 163

Registration Number: NCT05547386

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer

Conditions: Anatomic Stage III Breast Cancer AJCC V8
Locally Advanced Breast Carcinoma
Resectable Breast Carcinoma

Interventions: Procedure: Magnetic Resonance Imaging
Procedure: Mammogram
Procedure: Ultrasound
Procedure: Ultrasound-Guided Biopsy
Device: Twinkle marker

First Posted Date: 2022-09-21

Last Posted Date: 2023-10-05

Lead Sponsor: Mayo Clinic

Target Recruit Count: 10

Registration Number: NCT05547347

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

Not Applicable

Recruiting

Conditions: Lung Transplant

Interventions: Procedure: Off-pump lung transplantation
Procedure: Venoarterial ECMO lung transplantation

First Posted Date: 2022-09-21

Last Posted Date: 2024-04-03

Lead Sponsor: Mayo Clinic

Target Recruit Count: 228

Registration Number: NCT05547698

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
🇩🇪
Hannover Medical School, Hannover, Germany

and more 4 locations

A Study of Paravertebral Block in Thoracic Outlet Syndrome

Phase 4

Conditions: Thoracic Outlet Syndrome

Interventions: Drug: Ropivacaine

First Posted Date: 2022-09-16

Last Posted Date: 2024-12-05

Lead Sponsor: Mayo Clinic

Target Recruit Count: 50

Registration Number: NCT05544721

Locations: 🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

Phase 2

Recruiting

Conditions: Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Interventions: Procedure: Biospecimen Collection
Procedure: Computed Tomography
Drug: Cisplatin
Procedure: Magnetic Resonance Imaging
Radiation: Diffusing Alpha-emitter Radiation Therapy
Procedure: Modified Barium Swallow Study
Procedure: Intensity-Modulated Proton Therapy
Drug: Docetaxel
Other: Observation
Radiation: Intensity-Modulated Radiation Therapy
Procedure: Positron Emission Tomography
Other: Quality-of-Life Assessment
Other: Questionnaire

First Posted Date: 2022-09-15

Last Posted Date: 2024-08-29

Lead Sponsor: Mayo Clinic

Target Recruit Count: 320

Registration Number: NCT05541016

Locations: 🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States
🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
🇺🇸
Mayo Clinic in Arizona, Scottsdale, Arizona, United States

Effect of Acute Exercise on Exosome Associated Biomarkers

Active, not recruiting

Conditions: Healthy

First Posted Date: 2022-09-15

Last Posted Date: 2024-07-24

Lead Sponsor: Mayo Clinic

Target Recruit Count: 12

Registration Number: NCT05541133

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function

Early Phase 1

Recruiting

Conditions: Healthy

Interventions: Drug: Indomethacin
Dietary Supplement: S. boulardii CNCM I-745
Drug: Placebo

First Posted Date: 2022-09-13

Last Posted Date: 2025-01-06

Lead Sponsor: Mayo Clinic

Target Recruit Count: 56

Registration Number: NCT05538247

Locations: 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis

Not Applicable

Completed

Conditions: Stroke
Upper Extremity Weakness

Interventions: Device: Sequential Compression Device

First Posted Date: 2022-09-10

Last Posted Date: 2025-01-09

Lead Sponsor: Mayo Clinic

Target Recruit Count: 20

Registration Number: NCT05535257

Locations: 🇺🇸
C Joseph Yelvington, Saint Johns, Florida, United States

Home Terms & Conditions Privacy Policy