VA Office of Research and Development

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Ownership: Private

Employees: -

Market Cap: -

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Clinical Trials

N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy

Phase 2

Completed

Conditions: Diabetic Nephropathy
Proteinuria
Oxidative Stress

Interventions: Drug: N-acetylcysteine placebo and silibin placebo
Drug: N-acetylcysteine placebo and silibin active
Drug: N-acetylcysteine active and silibin active
Drug: N-acetylcysteine active and silibin placebo
Drug: N-acetylcysteine active + high-dose silibin active

First Posted Date: 2010-12-23

Last Posted Date: 2018-10-19

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 108

Registration Number: NCT01265563

Locations: 🇺🇸
South Texas Health Care System, San Antonio, TX, San Antonio, Texas, United States

A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors

Phase 3

Completed

Conditions: GERD

Interventions: Device: Nissen fundoplication
Drug: baclofen
Drug: Desipramine

First Posted Date: 2010-12-23

Last Posted Date: 2020-01-22

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 366

Registration Number: NCT01265550

Locations: 🇺🇸
Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama, United States
🇺🇸
VA Loma Linda Healthcare System, Loma Linda, CA, Loma Linda, California, United States
🇺🇸
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts, United States

and more 12 locations

Using Telemedicine to Improve Veteran Sleep Apnea Care

Phase 1

Completed

Conditions: Sleep Apnea Syndromes

Interventions: Behavioral: Usual Care
Behavioral: Video Teleconferencing Care

First Posted Date: 2010-12-14

Last Posted Date: 2015-11-04

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 23

Registration Number: NCT01259440

Locations: 🇺🇸
VA San Diego Healthcare System, San Diego, California, United States

Reducing Internalized Stigma in People With Serious Mental Illness

Phase 2

Completed

Conditions: Bipolar Disorder
Major Depression With Psychotic Features
Schizophrenia
Schizoaffective Disorder

Interventions: Behavioral: Health and Wellness Group
Behavioral: Ending Self Stigma (ESS)

First Posted Date: 2010-12-14

Last Posted Date: 2016-03-08

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 252

Registration Number: NCT01259427

Locations: 🇺🇸
Washington DC VA Medical Center, Washington, DC, Washington, District of Columbia, United States
🇺🇸
VA Maryland Health Care System, Baltimore, Baltimore, Maryland, United States
🇺🇸
Perry Point VA Medical Center VA Maryland Health Care System, Perry Point, MD, Perry Point, Maryland, United States

A Pilot Study of Lithium in Progressive Multiple Sclerosis

Phase 1

Completed

Conditions: Multiple Sclerosis

Interventions: Drug: Lithium Carbonate

First Posted Date: 2010-12-14

Last Posted Date: 2019-09-10

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 23

Registration Number: NCT01259388

Locations: 🇺🇸
Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama, United States
🇺🇸
Kirklin Clinic, Birmingham, Alabama, United States

Working Memory Changes With Aging and Hearing Loss

Completed

Conditions: Hearing Loss
Aging

First Posted Date: 2010-12-03

Last Posted Date: 2015-12-23

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 63

Registration Number: NCT01253031

Locations: 🇺🇸
VA Portland Health Care System, Portland, OR, Portland, Oregon, United States

Evaluation of Robot Assisted Neuro-Rehabilitation

Phase 1

Completed

Conditions: Stroke

Interventions: Behavioral: Robot Therapy
Behavioral: Transition to Task Training

First Posted Date: 2010-12-03

Last Posted Date: 2019-10-30

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 59

Registration Number: NCT01253018

Locations: 🇺🇸
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland, United States

"Hub and Satellite" Heart Failure Provider's Network Study

Not Applicable

Completed

Conditions: Heart Failure

Interventions: Other: No HF training
Other: HF training

First Posted Date: 2010-11-23

Last Posted Date: 2019-10-30

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 6

Registration Number: NCT01246050

Locations: 🇺🇸
Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville, Tennessee, United States

Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental Illness

Not Applicable

Completed

Conditions: Bipolar Disorder
Schizophrenia
Major Depressive Disorder
Chronic Affective Disorders
Cardiovascular Disease Risk

Interventions: Behavioral: Life Goals Collaborative Care

First Posted Date: 2010-11-19

Last Posted Date: 2017-06-06

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 55

Registration Number: NCT01244854

Locations: 🇺🇸
VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan, United States

Neuroimaging the Impact of Treatment on Neural Substrates of Trust in Post-Traumatic Stress Disorder (PTSD)

Not Applicable

Completed

Conditions: Trust
Stress Disorders, Post Traumatic

Interventions: Behavioral: Group CPT-C

First Posted Date: 2010-11-19

Last Posted Date: 2019-06-27

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 61

Registration Number: NCT01244477

Locations: 🇺🇸
Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas, United States

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