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JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Perampanel in Seizure Patients With Primary Glial Brain Tumors

Phase 4

Completed

Conditions: Brain Tumor, Primary

Interventions: Drug: Perampanel

First Posted Date: 2015-02-16

Last Posted Date: 2018-04-27

Lead Sponsor: Duke University

Target Recruit Count: 9

Registration Number: NCT02363933

Locations: 🇺🇸
The Preston Robert Tisch Brain Tumor Center, Durham, North Carolina, United States

Hyperbaric VO2max Study

Phase 2

Terminated

Conditions: Exercise Training

Interventions: Procedure: Normoxic, normobaric, interval exercise training
Procedure: Hyperoxic hyperbaric interval exercise training
Drug: Oxygen

First Posted Date: 2015-02-05

Last Posted Date: 2017-05-17

Lead Sponsor: Duke University

Target Recruit Count: 25

Registration Number: NCT02356900

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Men With Metastatic Castrate-Resistant Prostate Cancer Treated With Either Sipuleucel-T (Provenge®), Abiraterone Acetate (Zytiga®) or Enzalutamide (Xtandi®) Undergoing Cardiopulmonary EXercise Testing

Completed

Conditions: Prostate Cancer

Interventions: Drug: Abiraterone acetate
Drug: Enzalutamide
Drug: Sipuleucel-T

First Posted Date: 2015-02-03

Last Posted Date: 2020-12-24

Lead Sponsor: Duke University

Target Recruit Count: 38

Registration Number: NCT02353715

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Oral Water Hydration to Prevent Post-Vaccination Presyncope

Not Applicable

Completed

Conditions: Syncope
Presyncope

Interventions: Other: Oral Water Hydration

First Posted Date: 2015-02-02

Last Posted Date: 2016-07-07

Lead Sponsor: Duke University

Target Recruit Count: 1820

Registration Number: NCT02353390

Locations: 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Efficacy and Safety of Low Amplitude Electroconvulsive Therapy

Not Applicable

Terminated

Conditions: Depression

Interventions: Device: MECTA Spectrum 5000Q

First Posted Date: 2015-01-30

Last Posted Date: 2017-03-22

Lead Sponsor: Duke University

Target Recruit Count: 1

Registration Number: NCT02351843

Locations: 🇺🇸
DukeUMC, Durham, North Carolina, United States

Exercise Intervention for Cancer Survivors

Not Applicable

Completed

Conditions: Neoplasms

Interventions: Behavioral: Exercise OE workbook
Behavioral: Diet workbook

First Posted Date: 2015-01-28

Last Posted Date: 2017-01-27

Lead Sponsor: Duke University

Target Recruit Count: 64

Registration Number: NCT02348710

Locations: 🇺🇸
Duke University School of Nursing, Durham, North Carolina, United States

Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya

Not Applicable

Completed

Conditions: Severe Sepsis
Sepsis
Septic Shock

Interventions: Other: WHO algorithm of fluid boluses guided by physical examination
Other: Frequent patient monitoring
Other: Early administration of empiric antibiotics
Other: Oxygen delivery
Other: Correction of hypoglycemia
Other: Correction of severe anemia

First Posted Date: 2015-01-27

Last Posted Date: 2018-01-05

Lead Sponsor: Duke University

Target Recruit Count: 198

Registration Number: NCT02346331

Locations: 🇰🇪
Moi Teaching and Referral Hospital, Eldoret, Kenya

Use of a Perineometer to Assess Pelvic Muscle Tone

Withdrawn

Conditions: Pelvic Pain

First Posted Date: 2015-01-26

Last Posted Date: 2016-06-20

Lead Sponsor: Duke University

Registration Number: NCT02345538

Lifestyle Interventions in Treatment-Resistant Hypertension

Not Applicable

Completed

Conditions: Treatment-Resistant Hypertension

Interventions: Behavioral: Structured center-based lifestyle intervention
Behavioral: Standard education and physician advice

First Posted Date: 2015-01-21

Last Posted Date: 2021-02-04

Lead Sponsor: Duke University

Target Recruit Count: 140

Registration Number: NCT02342808

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Patient and Provider Assessment of Lipid Management Registry

Completed

Conditions: Diabetes
Chronic Kidney Disease (CKD)
Myocardial Infarction (MI)
Coronary Artery Disease (CAD)
Stroke
Transient Ischemic Attack (TIA)
Carotid Stenosis
Cardiovascular Disease
Unstable Angina
Atherosclerosis

First Posted Date: 2015-01-19

Last Posted Date: 2020-03-02

Lead Sponsor: Duke University

Target Recruit Count: 7658

Registration Number: NCT02341664

Locations: 🇺🇸
HealthEast Clinical Trials Office, Saint Paul, Minnesota, United States
🇺🇸
Cardiology and Medicine Clinic, Little Rock, Arkansas, United States
🇺🇸
Krishnan Challappa, MD, PSC, Elizabethtown, Kentucky, United States

and more 11 locations

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