JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Comparing Effectiveness of CSE Versus DPE for Labor Analgesia

Phase 4

Completed

Conditions: Labor Pain

Interventions: Drug: Ropivacaine 0.1% Injectable Solution
Drug: Bupivacaine 0.25% Injectable Solution

First Posted Date: 2021-10-06

Last Posted Date: 2024-11-06

Lead Sponsor: Duke University

Target Recruit Count: 101

Registration Number: NCT05068661

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Caremap: A Digital Personal Health Record for Complex Care Coordination

Not Applicable

Completed

Conditions: Adults With Multiple Chronic Conditions
Children/Youth With Special Healthcare Needs

Interventions: Other: Caremap app

First Posted Date: 2021-09-24

Last Posted Date: 2024-11-21

Lead Sponsor: Duke University

Target Recruit Count: 17

Registration Number: NCT05056493

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

Recruiting

Conditions: Critically Ill
Children, Adult
Cardiac Disease

Interventions: Drug: The OPTIC study is collecting PK data on children prescribed understudied drugs of interest per standard of care.

First Posted Date: 2021-09-24

Last Posted Date: 2024-10-09

Lead Sponsor: Duke University

Target Recruit Count: 2000

Registration Number: NCT05055830

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Learning Health for Pediatric Complex Care Integration (PCCI)

Completed

Conditions: Children and Youth With Special Healthcare Needs
Care Coordination

Interventions: Other: Surveys

First Posted Date: 2021-09-24

Last Posted Date: 2022-10-13

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT05056480

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Test to Stay in School: COVID-19 Testing Following Exposure in School Communities

Not Applicable

Completed

Conditions: Covid19

Interventions: Other: COVID-19 Testing

First Posted Date: 2021-09-22

Last Posted Date: 2023-11-27

Lead Sponsor: Duke University

Target Recruit Count: 4733

Registration Number: NCT05052580

Locations: 🇺🇸
Participating NC School Districts, Durham, North Carolina, United States

Effect of Corticosteroid Injections on Blood Glucose

Terminated

Conditions: Diabetes Mellitus
Steroid Diabetes
Knee Osteoarthritis
Hip Osteoarthritis
Shoulder Osteoarthritis
Adhesive Capsulitis

First Posted Date: 2021-09-17

Last Posted Date: 2025-03-25

Lead Sponsor: Duke University

Target Recruit Count: 38

Registration Number: NCT05048264

Locations: 🇺🇸
Duke Sports Science Institute, Durham, North Carolina, United States

The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study

Not Applicable

Withdrawn

Conditions: Choroideremia

Interventions: Dietary Supplement: Vitamin A palmitate

First Posted Date: 2021-09-16

Last Posted Date: 2023-06-29

Lead Sponsor: Duke University

Registration Number: NCT05045703

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

Low Nicotine Cigarettes, Smoking, and Chronic Pain

Not Applicable

Active, not recruiting

Conditions: Chronic Pain
Smoking, Cigarette

Interventions: Other: SPECTRUM NRC 600/601 investigational cigarettes
Other: SPECTRUM NRC 102/103 investigational cigarettes

First Posted Date: 2021-09-02

Last Posted Date: 2024-06-27

Lead Sponsor: Duke University

Target Recruit Count: 36

Registration Number: NCT05032755

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Efficacy Testing of a Culturally Relevant Stigma Intervention With WLWH in Tanzania

Not Applicable

Completed

Conditions: Self Esteem
Hope
Self Efficacy
Depressive Symptoms
HIV
Stigma, Social

Interventions: Behavioral: Labda Siku Moja stigma reduction intervention

First Posted Date: 2021-09-02

Last Posted Date: 2025-05-29

Lead Sponsor: Duke University

Target Recruit Count: 167

Registration Number: NCT05033002

Locations: 🇹🇿
Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings

Not Applicable

Recruiting

Conditions: Mental Illness
Recurring Major Depressive Disorder
Bipolar Disorder
Schizoaffective Disorder
Schizophrenia
Tobacco Use Disorder
Persistent Depressive Disorder

Interventions: Device: Quit on the Go App (formerly "Learn to Quit " App)
Behavioral: Brief advice
Drug: Nicotine patch
Behavioral: Smartphone coaching
Drug: Nicotine gum
Drug: Nicotine Lozenges

First Posted Date: 2021-09-01

Last Posted Date: 2025-03-17

Lead Sponsor: Duke University

Target Recruit Count: 450

Registration Number: NCT05030272

Locations: 🇺🇸
University at Buffalo, Buffalo, New York, United States
🇺🇸
Duke University, Durham, North Carolina, United States
🇺🇸
Wake Forest Health Sciences, Winston-Salem, North Carolina, United States

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