JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM

Phase 2

Not yet recruiting

Conditions: Multiple Myeloma in Relapse
Multiple Myeloma, Refractory

Interventions: Drug: Selinexor 40 mg

First Posted Date: 2025-02-12

Last Posted Date: 2025-02-12

Lead Sponsor: Duke University

Target Recruit Count: 27

Registration Number: NCT06822972

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

Phase 2

Not yet recruiting

Conditions: Newly Diagnosed Glioblastoma

Interventions: Drug: Nivolumab
Drug: Relatlimab
Drug: TMZ
Radiation: Radiation Therapy

First Posted Date: 2025-02-10

Last Posted Date: 2025-02-10

Lead Sponsor: Duke University

Target Recruit Count: 92

Registration Number: NCT06816927

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae

Recruiting

Conditions: Neisseria Gonorrheae Infection

First Posted Date: 2025-02-07

Last Posted Date: 2025-04-27

Lead Sponsor: Duke University

Target Recruit Count: 3291

Registration Number: NCT06815536

Locations: 🇺🇸
San Francisco Public Health Laboratory, San Francisco, California, United States
🇺🇸
Indiana University School of Medicine, Indianapolis, Indiana, United States
🇺🇸
Mississippi State Department of Public Health, Jackson, Mississippi, United States

and more 5 locations

Urine Methylation Markers in UTUC

Not Applicable

Recruiting

Conditions: Upper Tract Urothelial Cancer

First Posted Date: 2025-02-03

Last Posted Date: 2025-05-22

Lead Sponsor: Duke University

Target Recruit Count: 50

Registration Number: NCT06805630

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Designing a Virtual Reality Intervention to Improve Physical and Psychological Health in Intensive Care Units

Not Applicable

Recruiting

Conditions: Mobility
ICU
Heart Surgery
Nursing

First Posted Date: 2025-01-29

Last Posted Date: 2025-01-29

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT06797895

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Food is Medicine: Pilot Study

Not Applicable

Active, not recruiting

Conditions: Weight Loss

First Posted Date: 2025-01-28

Last Posted Date: 2025-05-18

Lead Sponsor: Duke University

Target Recruit Count: 43

Registration Number: NCT06797453

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Rare Glycogen Storage Diseases Natural History Study

Recruiting

Conditions: GSD XIII
GSD XV
Glycogen Storage Disease
GSD Type 0A
GSD Type 0B
GSD VII
Tarui Disease
GSD X
GSD XII
Polyglucosan Body Myopathy 2

First Posted Date: 2025-01-27

Last Posted Date: 2025-01-28

Lead Sponsor: Duke University

Target Recruit Count: 200

Registration Number: NCT06795152

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.

Not Applicable

Not yet recruiting

Conditions: Stroke
Stroke Patients
Arm Weakness as a Consequence of Stroke
Brain Stimulation
Transcranial Magnetic Stimulation Repetitive
Transcranial Magnetic Stimulation
Motor Learning
Chronic Stroke Patients
Chronic Stroke Survivors

First Posted Date: 2025-01-09

Last Posted Date: 2025-02-26

Lead Sponsor: Duke University

Target Recruit Count: 26

Registration Number: NCT06765642

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Allopregnanolone in Post-Stroke Depression

Phase 2

Not yet recruiting

Conditions: Post Stroke Depression

Interventions: Drug: Zuranolone

First Posted Date: 2025-01-06

Last Posted Date: 2025-05-31

Lead Sponsor: Duke University

Target Recruit Count: 6

Registration Number: NCT06759558

Locations: 🇺🇸
Duke South Neurology Clinic 1L, Durham, North Carolina, United States

Genetic Testing to Understand and Address Renal Disease Disparities Across the United States Pharmacogenetic Substudy

Not Applicable

Completed

Conditions: Chronic Kidney Disease
Hypertension

First Posted Date: 2024-12-24

Last Posted Date: 2025-04-30

Lead Sponsor: Duke University

Target Recruit Count: 1874

Registration Number: NCT06748040

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of Florida - Gainesville, Gainesville, Florida, United States
🇺🇸
University of Florida - Jacksonville, Jacksonville, Florida, United States

and more 5 locations

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