JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Stool Transplants to Treat Refractory Clostridium Difficile Colitis

Phase 2

Recruiting

Conditions: Clostridium Difficile Colitis

Interventions: Biological: fecal microbiota

First Posted Date: 2014-04-30

Last Posted Date: 2024-07-24

Lead Sponsor: Duke University

Target Recruit Count: 77

Registration Number: NCT02127398

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

The Effect of Oral Carnitine Supplementation on MRS-derived Mitochondrial Function

Not Applicable

Completed

Conditions: Elderly
Pre-diabetic

Interventions: Other: Acute Exercise

First Posted Date: 2014-04-28

Last Posted Date: 2015-06-17

Lead Sponsor: Duke University

Target Recruit Count: 14

Registration Number: NCT02124590

Locations: 🇺🇸
Duke Center for Living, Durham, North Carolina, United States

Community-Driven Cervical Cancer Prevention in Western Kenya

Not Applicable

Completed

Conditions: Human Papilloma Virus Infection
Carcinoma in Situ of Uterine Cervix

Interventions: Behavioral: Community-based HPV testing with enhanced linkage to care
Behavioral: Community-based testing with standard linkage to care

First Posted Date: 2014-04-28

Last Posted Date: 2019-04-10

Lead Sponsor: Duke University

Target Recruit Count: 7200

Registration Number: NCT02124252

Locations: 🇰🇪
Kenya Medical Research Institute, Nairobi, Kenya

Exercise, Heart Failure, and Type 2 Diabetes

Not Applicable

Withdrawn

Conditions: Heart Failure
Type 2 Diabetes

Interventions: Behavioral: aerobic exercise training

First Posted Date: 2014-04-25

Last Posted Date: 2023-06-15

Lead Sponsor: Duke University

Registration Number: NCT02122835

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Dynamics of the Microbiome in the Premature Infant

Completed

Conditions: Infection

First Posted Date: 2014-04-24

Last Posted Date: 2024-04-12

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT02121938

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Safety Study of Regorafenib With PF-03446962 to Treat Colorectal Cancer

Phase 1

Completed

Conditions: Colorectal Cancer

Interventions: Biological: PF-03446962
Drug: Regorafenib

First Posted Date: 2014-04-17

Last Posted Date: 2019-03-14

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT02116894

Locations: 🇺🇸
Duke Cancer Center, Duke University Medical Center, Durham, North Carolina, United States

Mobile Sensing of Smoking Behavior

Not Applicable

Completed

Conditions: Smoking
Health

First Posted Date: 2014-04-16

Last Posted Date: 2014-11-05

Lead Sponsor: Duke University

Target Recruit Count: 2

Registration Number: NCT02116283

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Trial of Neoadjuvant Ipilimumab Followed by Melphalan Via Isolated Limb Infusion for Patients With Unresectable In-transit Extremity Melanoma

Phase 1

Completed

Conditions: Unresectable Melanoma

Interventions: Drug: Ipilimumab

First Posted Date: 2014-04-15

Last Posted Date: 2018-10-29

Lead Sponsor: Duke University

Target Recruit Count: 4

Registration Number: NCT02115243

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

Phase 2

Completed

Conditions: ATIII Deficiency

Interventions: Drug: Anti-thrombin III
Other: Placebo

First Posted Date: 2014-04-03

Last Posted Date: 2019-11-25

Lead Sponsor: Duke University

Target Recruit Count: 45

Registration Number: NCT02103114

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Older Cancer Caregiver Needs Post Hospital Discharge

Completed

Conditions: Cancer Caregivers of Older Adults

First Posted Date: 2014-03-31

Last Posted Date: 2015-07-23

Lead Sponsor: Duke University

Target Recruit Count: 23

Registration Number: NCT02099526

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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