JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

Early Phase 1

Recruiting

Conditions: Adverse Childhood Experiences
Nicotine Dependence, Cigarettes

Interventions: Drug: Placebo
Drug: Nicotine nasal spray 0.5 mg

First Posted Date: 2022-12-27

Last Posted Date: 2024-04-01

Lead Sponsor: Duke University

Target Recruit Count: 150

Registration Number: NCT05665465

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Engaging African American Older Adults With Arthritis in a Physical Activity Intervention

Not Applicable

Completed

Conditions: Osteoarthritis, Hip
Osteoarthritis, Knee

Interventions: Behavioral: Adapted-Engage-PA

First Posted Date: 2022-12-15

Last Posted Date: 2023-07-27

Lead Sponsor: Duke University

Target Recruit Count: 16

Registration Number: NCT05652413

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

The WISER Study: Web Based Methods for Enhancing Resilience

Not Applicable

Recruiting

Conditions: Burnout

Interventions: Behavioral: WISER

First Posted Date: 2022-12-05

Last Posted Date: 2023-12-20

Lead Sponsor: Duke University

Target Recruit Count: 8000

Registration Number: NCT05636072

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Patient Initiated Note About Goals

Not Applicable

Recruiting

Conditions: Chronic Disease

Interventions: Behavioral: PING

First Posted Date: 2022-12-05

Last Posted Date: 2024-01-11

Lead Sponsor: Duke University

Target Recruit Count: 800

Registration Number: NCT05637489

Locations: 🇺🇸
Duke Health, Durham, North Carolina, United States

Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer

Phase 4

Recruiting

Conditions: Pancreatic Ductal Adenocarcinoma

Interventions: Drug: HA Chemotherapy

First Posted Date: 2022-12-02

Last Posted Date: 2024-01-18

Lead Sponsor: Duke University

Target Recruit Count: 40

Registration Number: NCT05634720

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

Early Phase 1

Recruiting

Conditions: Primary Brain Tumor
Brain Tumor, Recurrent

Interventions: Drug: Fluoxetine
Drug: Temozolomide

First Posted Date: 2022-12-02

Last Posted Date: 2024-11-06

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT05634707

Locations: 🇺🇸
NYU Langone Health, New York, New York, United States
🇺🇸
UC San Diego Moores Cancer Center, San Diego, California, United States
🇺🇸
The Preston Robert Tisch Brain Tumor Center at Duke University, Durham, North Carolina, United States

Implementation of the ACP Guideline for Low Back Pain (IMPACt-LBP)

Phase 4

Recruiting

Conditions: Pain, Back

Interventions: Other: Primary Spine Provider Model
Other: Usual Care

First Posted Date: 2022-11-23

Last Posted Date: 2024-04-19

Lead Sponsor: Duke University

Target Recruit Count: 1800

Registration Number: NCT05626049

Locations: 🇺🇸
University of Iowa, Iowa City, Iowa, United States
🇺🇸
Duke Health, Durham, North Carolina, United States
🇺🇸
Dartmouth Health, Lebanon, New Hampshire, United States

DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia

Early Phase 1

Recruiting

Conditions: Coats' Disease
Exudative Retinopathy
Retinal Hole
Sickler's Syndrome
Retinal Detachment Rhegmatogenous
Vitreoretinopathy
Lattice Degeneration
Retinal Detachment Exudative
Retinal Detachment Traction

Interventions: Drug: Dextenza 0.4Mg Ophthalmic Insert
Drug: Pred Forte

First Posted Date: 2022-11-17

Last Posted Date: 2023-07-27

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT05620901

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

Pilot Testing of an Equity Focused and Trauma-informed Communication Intervention During Family-centered Rounds

Not Applicable

Recruiting

Conditions: Hospitalism in Children
Post Traumatic Stress Disorder

Interventions: Behavioral: Equity Focused and Trauma-Informed Communication Intervention

First Posted Date: 2022-11-16

Last Posted Date: 2024-12-03

Lead Sponsor: Duke University

Target Recruit Count: 120

Registration Number: NCT05618652

Locations: 🇺🇸
Duke University Health Sustem, Durham, North Carolina, United States

FlexED: A Digital, Gamified Early Intervention for Eating Disorders

Not Applicable

Recruiting

Conditions: Body Image
Eating Disorders

Interventions: Behavioral: FlexED

First Posted Date: 2022-11-08

Last Posted Date: 2024-06-17

Lead Sponsor: Duke University

Target Recruit Count: 24

Registration Number: NCT05609409

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

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