JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Duke COVID-19 Shared Data and Specimen Repository

Recruiting

Conditions: COVID-19

First Posted Date: 2020-04-29

Last Posted Date: 2024-05-21

Lead Sponsor: Duke University

Target Recruit Count: 100000

Registration Number: NCT04368234

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Individual Patient Exposure and Response in Pediatric Lupus

Not Applicable

Completed

Conditions: Systemic Lupus Erythematosus

Interventions: Behavioral: Pillsy

First Posted Date: 2020-04-24

Last Posted Date: 2024-07-15

Lead Sponsor: Duke University

Target Recruit Count: 26

Registration Number: NCT04358302

Locations: 🇺🇸
Duke Clinical Research Institute, Durham, North Carolina, United States

Assessing the System for High-Intensity Evaluation During Radiotherapy During Changes in Response to COVID-19

Conditions: COVID-19
Cancer

Interventions: Other: Telehealth

First Posted Date: 2020-04-22

Last Posted Date: 2024-11-01

Lead Sponsor: Duke University

Target Recruit Count: 1000

Registration Number: NCT04357574

Locations: 🇺🇸
Duke Cancer Center, Durham, North Carolina, United States

Weight Loss and Exercise To Improve Rheumatoid Arthritis Cardiovascular Risk

Not Applicable

Completed

Conditions: Rheumatoid Arthritis

First Posted Date: 2020-04-22

Last Posted Date: 2024-03-08

Lead Sponsor: Duke University

Target Recruit Count: 24

Registration Number: NCT04356183

Locations: 🇺🇸
Duke Center for Living, Durham, North Carolina, United States

Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

Phase 2

Active, not recruiting

Conditions: Metastatic Breast Cancer
Hormone Receptor Positive Tumor
Locally Advanced Breast Cancer

Interventions: Drug: Abemaciclib
Drug: Aromatase Inhibitors
Drug: Fulvestrant

First Posted Date: 2020-04-20

Last Posted Date: 2024-02-14

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT04352777

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Aspirin for Prevention of Venous Thromboembolism Among Ovarian Cancer Patients Receiving Neoadjuvant Chemotherapy

Phase 4

Completed

Conditions: Venous Thromboembolism
Ovarian Cancer

Interventions: Drug: Aspirin

First Posted Date: 2020-04-20

Last Posted Date: 2022-09-26

Lead Sponsor: Duke University

Target Recruit Count: 19

Registration Number: NCT04352439

Locations: 🇺🇸
Sarasota Memorial HealthCare System, Sarasota, Florida, United States
🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Assessing Muscle Metabolic Phenotype by MSK Ultrasound

Suspended

Conditions: Ultrasound
CT
MuscleSound

First Posted Date: 2020-04-20

Last Posted Date: 2023-12-12

Lead Sponsor: Duke University

Target Recruit Count: 200

Registration Number: NCT04353648

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Identifying the Optimal Neural Target for Misophonia Interventions

Not Applicable

Completed

Conditions: Misophonia
Emotion Dysregulation

Interventions: Behavioral: Cognitive Restructuring
Device: neurostimulation

First Posted Date: 2020-04-16

Last Posted Date: 2023-08-25

Lead Sponsor: Duke University

Target Recruit Count: 59

Registration Number: NCT04348591

Locations: 🇺🇸
Duke University Medical Center-Civitan Bldg, Durham, North Carolina, United States

Longitudinal Energy Expenditure and Metabolic Effects in Patients With COVID-19 (LEEP-COVID)

Completed

Conditions: COVID-19

Interventions: Device: Q-NRG Metobolic Cart Device
Device: MuscleSound Ultrasound
Device: Multifrequency Bioimpedance Spectroscopy

First Posted Date: 2020-04-16

Last Posted Date: 2023-05-16

Lead Sponsor: Duke University

Target Recruit Count: 65

Registration Number: NCT04350073

Locations: 🇺🇸
Duke University Medial Center, Durham, North Carolina, United States

Persistent Postpartum Hypertension Pilot Trial

Phase 4

Terminated

Conditions: Hypertension in Pregnancy

Interventions: Drug: Nifedipine Extended-Release Tablets

First Posted Date: 2020-04-16

Last Posted Date: 2023-04-03

Lead Sponsor: Duke University

Target Recruit Count: 12

Registration Number: NCT04349124

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

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