JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Phase II Clinical Trial of Clenbuterol in Adult Patients With Pompe Disease

Phase 2

Withdrawn

Conditions: Pompe Disease (Late-onset)

Interventions: Drug: Placebos
Drug: Clenbuterol

First Posted Date: 2019-09-19

Last Posted Date: 2022-08-17

Lead Sponsor: Duke University

Registration Number: NCT04094948

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

Not Applicable

Terminated

Conditions: All-cause Mortality
Hospitalization

Interventions: Procedure: Hemodialysis

First Posted Date: 2019-09-19

Last Posted Date: 2025-01-08

Lead Sponsor: Duke University

Target Recruit Count: 793

Registration Number: NCT04095039

Locations: 🇺🇸
DaVita El Dorado Dialysis, Long Beach, California, United States
🇺🇸
DaVita Troup County Dialysis, LaGrange, Georgia, United States
🇺🇸
DaVita Ouachita Valley, Camden, Arkansas, United States

and more 81 locations

Improving Lung Transplant Outcomes With Coping Skills and Physical Activity

Not Applicable

Active, not recruiting

Conditions: Post-Lung Transplantation

Interventions: Behavioral: Standard of Care plus Education (SOC-ED)
Behavioral: Coping Skills Training combined with Exercise (CSTEX)

First Posted Date: 2019-09-18

Last Posted Date: 2024-05-14

Lead Sponsor: Duke University

Target Recruit Count: 180

Registration Number: NCT04093869

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Varenicline Light Smoking Pilot

Phase 4

Completed

Conditions: Smoking Cessation
Smoking Behaviors
Smoking

Interventions: Drug: Varenicline
Drug: Placebo oral tablet

First Posted Date: 2019-09-16

Last Posted Date: 2021-05-11

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT04089982

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data Registry

Recruiting

Conditions: Oligometastasis
Metastatic Cancer

First Posted Date: 2019-09-11

Last Posted Date: 2024-03-15

Lead Sponsor: Duke University

Target Recruit Count: 1000

Registration Number: NCT04085029

Locations: 🇺🇸
Duke Cancer Institute Cary, Cary, North Carolina, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸
Duke Women's Cancer Care Raleigh, Raleigh, North Carolina, United States

and more 2 locations

Diet and Hypertension Management in African Americans With Chronic Kidney Disease

Not Applicable

Completed

Conditions: Chronic Kidney Diseases
High Blood Pressure

Interventions: Behavioral: DASH diet counseling

First Posted Date: 2019-09-10

Last Posted Date: 2025-01-06

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT04084574

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer

Completed

Conditions: Primary Brain Tumor
Brain Metastases, Adult

Interventions: Other: Neuropsychological Testing

First Posted Date: 2019-08-30

Last Posted Date: 2023-01-20

Lead Sponsor: Duke University

Target Recruit Count: 33

Registration Number: NCT04075370

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Virtual Reality for Improving Pain and Distress in Patients With Advanced Stage Colorectal Cancer

Not Applicable

Completed

Conditions: Colorectal Cancer

Interventions: Behavioral: VR Blue

First Posted Date: 2019-08-28

Last Posted Date: 2023-07-10

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT04069702

Locations: 🇺🇸
Duke Cancer Institute, Durham, North Carolina, United States

Genentech Xenon MRI Idiopathic Pulmonary Fibrosis

Phase 2

Active, not recruiting

Conditions: Idiopathic Pulmonary Fibrosis

Interventions: Drug: Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment

First Posted Date: 2019-08-28

Last Posted Date: 2024-12-10

Lead Sponsor: Duke University

Target Recruit Count: 34

Registration Number: NCT04071769

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

An Opioid Prescribing Nudge

Not Applicable

Completed

Conditions: Benzodiazepine Dependent
Prescription Drug Abuse (Not Dependent)
Opioid Use, Unspecified
Health Behavior
Prescription Drug Abuse and Dependency
Benzodiazepine Abuse

Interventions: Other: Automated Reports on prescription patterns for their patients

First Posted Date: 2019-08-28

Last Posted Date: 2020-06-30

Lead Sponsor: Duke University

Target Recruit Count: 427

Registration Number: NCT04069403

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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