MedPath

Clenbuterol

Generic Name
Clenbuterol
Drug Type
Small Molecule
Chemical Formula
C12H18Cl2N2O
CAS Number
37148-27-9
Unique Ingredient Identifier
XTZ6AXU7KN
Background

A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.

Indication

Used as a bronchodilator in the treatment of asthma patients.

Associated Conditions
Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Lung Disorder

Clenbuterol to Target DUX4 in FSHD

Phase 1
Not yet recruiting
Conditions
Muscular Dystrophy, Facioscapulohumeral
Interventions
First Posted Date
2024-12-06
Last Posted Date
2025-03-26
Lead Sponsor
Jeffrey Statland
Target Recruit Count
30
Registration Number
NCT06721299
Locations
🇺🇸

University of Kansas Medical Center, Kansas City, Kansas, United States

🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

🇺🇸

University of Washington, Seattle, Washington, United States

A Placebo-controlled Study of Clenbuterol in Spinal and Bulbar Muscular Atrophy

Phase 2
Recruiting
Conditions
Spinal and Bulbar Muscular Atrophy
Interventions
Drug: Placebo
First Posted Date
2023-12-13
Last Posted Date
2024-04-15
Lead Sponsor
Gianni Soraru
Target Recruit Count
90
Registration Number
NCT06169046
Locations
🇮🇹

Azienda Ospedale Università di Padova, Padova, PD, Italy

Muscle Memory After Treatment With Anabolic Substance Clenbuterol and Resistance Training in Humans

Not Applicable
Recruiting
Conditions
Skeletal Muscle Physiology
Interventions
Drug: Placebo
First Posted Date
2023-01-20
Last Posted Date
2023-01-20
Lead Sponsor
Morten Hostrup, PhD
Target Recruit Count
60
Registration Number
NCT05692856
Locations
🇩🇰

August Krogh Building, Copenhagen, Denmark

Obese Human Beta-2-adrenergic Stimulation and Muscle Glucose Uptake

Phase 2
Completed
Conditions
Type 2 Diabetes
Interventions
First Posted Date
2021-06-10
Last Posted Date
2024-05-07
Lead Sponsor
Maastricht University
Target Recruit Count
14
Registration Number
NCT04921306
Locations
🇳🇱

Maastricht University, Maastricht, Netherlands

A Study of Clenbuterol (CST-103) Co-administered With Nadolol (CST-107) in Subjects With Neurodegenerative Disorders

Phase 2
Completed
Conditions
Mild Cognitive Impairment, Lewy Body Dementia, Parkinson's Disease Rapid Eye Movement Sleep Behavior Disorder, Parkinson's Disease Dementia
Interventions
First Posted Date
2021-02-04
Last Posted Date
2024-12-02
Lead Sponsor
CuraSen Therapeutics, Inc.
Target Recruit Count
41
Registration Number
NCT04739423
Locations
🇦🇺

The University of Sydney, Sydney, New South Wales, Australia

🇬🇧

MAC, Manchester, United Kingdom

🇳🇿

NZBRI, Christchurch, New Zealand

and more 2 locations

Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis

Phase 2
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2020-01-29
Last Posted Date
2022-09-06
Lead Sponsor
Dwight Koeberl, M.D., Ph.D.
Target Recruit Count
25
Registration Number
NCT04245709
Locations
🇺🇸

Duke University Medical center, Durham, North Carolina, United States

Phase II Clinical Trial of Clenbuterol in Adult Patients With Pompe Disease

Phase 2
Withdrawn
Conditions
Pompe Disease (Late-onset)
Interventions
Drug: Placebos
First Posted Date
2019-09-19
Last Posted Date
2022-08-17
Lead Sponsor
Duke University
Registration Number
NCT04094948
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Response to Clenbuterol in Humans

Not Applicable
Completed
Conditions
Healthy
Interventions
First Posted Date
2019-03-04
Last Posted Date
2024-08-09
Lead Sponsor
University of Copenhagen
Target Recruit Count
16
Registration Number
NCT03860870
Locations
🇩🇰

August Krogh Building, Copenhagen, Denmark

Human Beta-2 Adrenergic Stimulation and Muscle Glucose Uptake

Phase 2
Completed
Conditions
Healthy
Interventions
First Posted Date
2019-01-11
Last Posted Date
2022-12-01
Lead Sponsor
Maastricht University
Target Recruit Count
11
Registration Number
NCT03800290
Locations
🇳🇱

Maastricht University, Maastricht, Limburg, Netherlands

cAMP Signaling and Muscle Adaptations

Not Applicable
Conditions
Muscle Hypertrophy in Healthy Young Men
Interventions
Other: No training
Other: Endurance training
Other: Resistance Training
Drug: Placebo
First Posted Date
2015-09-23
Last Posted Date
2017-10-26
Lead Sponsor
University of Copenhagen
Target Recruit Count
72
Registration Number
NCT02557581
Locations
🇩🇰

Bispebjerg University Hospital, Copenhagen, Denmark

🇩🇰

Department of Nutrition, Exercise and Sports, Copenhagen, Denmark

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