JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Testing the Feasibility of the DASH Cloud Intervention Using Amazon Alexa

Not Applicable

Completed

Conditions: Behavior, Health
Diet Modification

Interventions: Behavioral: DASH cloud with Alexa

First Posted Date: 2018-03-07

Last Posted Date: 2019-07-25

Lead Sponsor: Duke University

Target Recruit Count: 26

Registration Number: NCT03455946

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Abdominal Nerve Blockade in Chronic Heart Failure.

Phase 1

Completed

Conditions: Heart Failure

Interventions: Drug: splanchnic nerve anesthesia with a local anesthetic

First Posted Date: 2018-03-05

Last Posted Date: 2020-07-24

Lead Sponsor: Duke University

Target Recruit Count: 19

Registration Number: NCT03453151

Locations: 🇺🇸
Duke, Durham, North Carolina, United States

Alpha MSH in Ocular Disease

Not Applicable

Completed

Conditions: Advanced Dry Macular Degeneration

Interventions: Device: Alpha MSH assay

First Posted Date: 2018-03-01

Last Posted Date: 2022-12-22

Lead Sponsor: Duke University

Target Recruit Count: 54

Registration Number: NCT03451578

Locations: 🇺🇸
Duke University Eye Center, Durham, North Carolina, United States

AML Electronic Decision Aid

Not Applicable

Completed

Conditions: Acute Myeloid Leukemia

Interventions: Other: Electronic Decision Aid Tool

First Posted Date: 2018-02-22

Last Posted Date: 2019-10-15

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT03442452

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Role of Social Incentives in PRO Collection

Completed

Conditions: Orthopedic Disorder

Interventions: Other: Interview

First Posted Date: 2018-02-19

Last Posted Date: 2019-12-17

Lead Sponsor: Duke University

Target Recruit Count: 8

Registration Number: NCT03436446

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Seizure Prophylaxis in Patients With Glioma or Brain Metastasis

Phase 2

Terminated

Conditions: Glioma of Brain
Brain Tumor
Glioma

Interventions: Drug: Lacosamide
Drug: Levetiracetam

First Posted Date: 2018-02-19

Last Posted Date: 2023-04-13

Lead Sponsor: Duke University

Target Recruit Count: 4

Registration Number: NCT03436433

Locations: 🇺🇸
Duke Comprehensive Cancer Center, Durham, North Carolina, United States

Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer

Not Applicable

Completed

Conditions: Early Detection of Cancer
Breast Neoplasms

Interventions: Behavioral: Control
Behavioral: Patient activation
Behavioral: Primary care physician activation

First Posted Date: 2018-02-19

Last Posted Date: 2023-09-08

Lead Sponsor: Duke University

Target Recruit Count: 314

Registration Number: NCT03435380

Locations: 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
🇺🇸
Hunter College, City of New York, New York, New York, United States
🇺🇸
Columbia University, New York, New York, United States

and more 2 locations

OCT Pilot in Esophagus

Not Applicable

Completed

Conditions: Barrett Esophagus

Interventions: Device: optical coherence tomography

First Posted Date: 2018-02-15

Last Posted Date: 2021-04-06

Lead Sponsor: Duke University

Target Recruit Count: 53

Registration Number: NCT03434834

Locations: 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

A Study Osimertinib in Patients With Stage 4 Non-small Cell Lung Cancer With Uncommon EGFR Mutations

Phase 2

Completed

Conditions: Non Small Cell Lung Cancer

Interventions: Drug: osimertinib

First Posted Date: 2018-02-15

Last Posted Date: 2023-10-17

Lead Sponsor: Duke University

Target Recruit Count: 17

Registration Number: NCT03434418

Locations: 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
🇺🇸
The Ohio State University Medical Center, Columbus, Ohio, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Ketogenic Diet for Reduction of CNS Oxygen Toxicity in Working Divers

Not Applicable

Completed

Conditions: CNS Oxygen Toxicity, Ketogenic Diet

Interventions: Dietary Supplement: Ketogenic Diet

First Posted Date: 2018-02-14

Last Posted Date: 2021-12-14

Lead Sponsor: Duke University

Target Recruit Count: 91

Registration Number: NCT03433261

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

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