JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

ACDF Comparison Trial

Not Applicable

Withdrawn

Conditions: Cervical Spine Disc Disease
Fusion of Spine
Surgery
Degenerative Disc Disease

Interventions: Device: Cohere PEEK Fusion Group
Other: Allograft Fusion

First Posted Date: 2017-06-14

Last Posted Date: 2019-05-13

Lead Sponsor: Duke University

Registration Number: NCT03187171

FLUAD® vs. Fluzone® High-Dose Study

Phase 4

Completed

Conditions: Pain
Quality of Life
Injection Site Reaction
Side Effect of Drug
Adverse Drug Event

Interventions: Biological: Fluzone® High-Dose
Biological: FLUAD®

First Posted Date: 2017-06-12

Last Posted Date: 2021-03-30

Lead Sponsor: Duke University

Target Recruit Count: 757

Registration Number: NCT03183908

Locations: 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
🇺🇸
Duke University, Durham, North Carolina, United States

and more 1 locations

Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)

Phase 4

Completed

Conditions: Malaria,Falciparum

Interventions: Drug: Sulfadoxine/Pyrimethanine-Amodiaquine (SP-AQ)
Drug: Dihydroartemisinin-Piperaquine (DP)
Drug: Proguanil Oral Tablet

First Posted Date: 2017-06-07

Last Posted Date: 2024-04-23

Lead Sponsor: Duke University

Target Recruit Count: 246

Registration Number: NCT03178643

Locations: 🇰🇪
Homa Bay County Referral Hospital, Homa Bay Town, Homa Bay County, Kenya

LITT Palliative Treatment for Patients With Malignant Gliomas

Withdrawn

Conditions: Glioblastoma
Malignant Glioma of Brain

Interventions: Other: Palliative regimen consisting of LITT

First Posted Date: 2017-06-05

Last Posted Date: 2019-02-27

Lead Sponsor: Duke University

Registration Number: NCT03176160

Locations: 🇺🇸
The Preston Robert Tisch Brain Tumor Center at Duke, Durham, North Carolina, United States

Williams LifeSkills - Cancer Caregiver Intervention

Not Applicable

Completed

Conditions: Cancer

Interventions: Behavioral: WLSCC
Other: Usual Care

First Posted Date: 2017-06-02

Last Posted Date: 2017-12-29

Lead Sponsor: Duke University

Target Recruit Count: 7

Registration Number: NCT03174626

Locations: 🇺🇸
Duke Cancer Center, Durham, North Carolina, United States

Self-activation in Individuals With and Without Nicotine Dependence

Not Applicable

Terminated

Conditions: Addiction Nicotine

Interventions: Device: Neurofeedback (from fMRI and/or EEG)

First Posted Date: 2017-05-31

Last Posted Date: 2023-07-21

Lead Sponsor: Duke University

Target Recruit Count: 47

Registration Number: NCT03170258

Locations: 🇺🇸
Center for Cognitive Neuroscience, Durham, North Carolina, United States

Phase II Multicenter Study of Durvalumab and Olaparib in Platinum tReated Advanced Triple Negative Breast Cancer (DORA)

Phase 2

Completed

Conditions: Triple Negative Breast Cancer

Interventions: Drug: Olaparib Oral Product
Drug: Olaparib Oral Product in combination with Durvalumab

First Posted Date: 2017-05-30

Last Posted Date: 2022-09-13

Lead Sponsor: Duke University

Target Recruit Count: 45

Registration Number: NCT03167619

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Fever After Simultaneous Versus Sequential Vaccination in Young Children

Phase 4

Completed

Conditions: Fever After Vaccination
Fever
Febrile Seizure

Interventions: Biological: PCV13
Biological: DTaP
Biological: IIV

First Posted Date: 2017-05-24

Last Posted Date: 2024-11-18

Lead Sponsor: Duke University

Target Recruit Count: 221

Registration Number: NCT03165981

Locations: 🇺🇸
Kaiser Permanente Northern California, Oakland, California, United States
🇺🇸
Duke University, Durham, North Carolina, United States
🇺🇸
Centers for Disease Control and Prevention, Atlanta, Georgia, United States

The Addition of Dry Needling in the Treatment of Patients With Patellofemoral Pain Syndrome

Not Applicable

Withdrawn

Conditions: Patellofemoral Pain Syndrome

Interventions: Other: Intramuscular Dry Needling

First Posted Date: 2017-05-17

Last Posted Date: 2017-12-15

Lead Sponsor: Duke University

Registration Number: NCT03157271

Intraoperative ICG for Systemic Sclerosis

Phase 4

Withdrawn

Conditions: Systemic Sclerosis

Interventions: Procedure: Order of two elements of surgical procedure
Drug: Indocyanine Green

First Posted Date: 2017-05-16

Last Posted Date: 2020-06-30

Lead Sponsor: Duke University

Registration Number: NCT03155464

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