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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Neisseria Meningitidis Burden of Disease Study

Completed
Conditions
Neisseria Meningitidis
Streptococcus Pneumoniae
Haemophilus Influenzae
Interventions
Other: Data collection
Other: CSF samples testing
First Posted Date
2012-11-21
Last Posted Date
2015-11-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
521
Registration Number
NCT01730391
Locations
🇻🇳

GSK Investigational Site, Hanoi, Vietnam

Immunogenicity and Safety of PrepandrixTM in Korean Subjects Aged 18 to 60 Years Old

Phase 4
Completed
Conditions
Influenza
Interventions
Biological: Prepandrix™
Biological: Fluarix™
First Posted Date
2012-11-21
Last Posted Date
2018-09-07
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
131
Registration Number
NCT01730378
Locations
🇰🇷

GSK Investigational Site, Seoul, Korea, Republic of

Safety and Effectiveness of BENLYSTA (Belimumab) in Systemic Lupus Erythematosus (SLE) Registry

Completed
Conditions
Systemic Lupus Erythematosus
Interventions
Other: SLE treatment
First Posted Date
2012-11-20
Last Posted Date
2025-05-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
3138
Registration Number
NCT01729455
Locations
🇸🇪

GSK Investigational Site, Stockholm, Sweden

To Investigate the Pharmacokinetics and Safety of Fluticasone Furoate (FF)/ Umeclidinium (UMEC) Combination Compared With FF and UMEC Monotherapies in Adult Healthy Volunteers Using a Dry Powder Inhaler (DPI)

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: FF 400 mcg
Drug: UMEC 500 mcg
Drug: FF/UMEC 400/500 mcg
First Posted Date
2012-11-14
Last Posted Date
2017-06-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
18
Registration Number
NCT01725685
Locations
🇺🇸

GSK Investigational Site, Baltimore, Maryland, United States

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

Phase 1
Terminated
Conditions
Diabetes Mellitus, Type 2
Interventions
Drug: Metformin, 1000 mg extended release tablet
Drug: Metformin, 1000 mg and Glimepiride, 2 mg extended release film coated tablet containing release controlling polymers
Drug: Metformin, 500 mg and Glimepiride, 1 mg extended release tablet coated with release controlling polymers
Drug: Metformin, 1000 mg and Glimepiride, 2 mg extended release tablet coated with release controlling polymers
Drug: Metformin, 500 mg extended release tablet
Drug: Metformin, 500 mg and Glimepiride, 1 mg extended release film coated tablet containing release controlling polymers
Drug: Glimepiride, 2 mg immediate release tablet
Drug: Glimepiride, 1 mg immediate release tablet
First Posted Date
2012-11-14
Last Posted Date
2017-06-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
20
Registration Number
NCT01725672
Locations
🇦🇺

GSK Investigational Site, Randwick, New South Wales, Australia

A Study to Determine the Relative Bioavailability of the MEK Inhibitor, Trametinib, in Subjects With Solid Tumor Malignancies

Phase 1
Completed
Conditions
Cancer
Interventions
Drug: GSK1120212B (Standard DMSO content)
Drug: GSK1120212B (Lower DMSO content)
First Posted Date
2012-11-12
Last Posted Date
2017-11-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
80
Registration Number
NCT01725100
Locations
🇺🇸

GSK Investigational Site, Nashville, Tennessee, United States

To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes

Phase 2
Completed
Conditions
Obesity
Interventions
First Posted Date
2012-11-12
Last Posted Date
2017-12-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
53
Registration Number
NCT01725126
Locations
🇺🇸

GSK Investigational Site, Overland Park, Kansas, United States

A Proof of Mechanism Study With GSK2126458 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Phase 1
Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Drug: Placebo
First Posted Date
2012-11-12
Last Posted Date
2019-11-21
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
17
Registration Number
NCT01725139
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

Dose-Optimization, Adjunctive Treatment Study of Ezogabine/Retigabine Immediate Release in Partial-onset Seizures

Phase 4
Terminated
Conditions
Seizures
Interventions
Drug: Placebo
Drug: Ezogabine/Retigabine IR
First Posted Date
2012-11-04
Last Posted Date
2020-12-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
6
Registration Number
NCT01721317
Locations
🇬🇷

GSK Investigational Site, Thessaloniki, Greece

A Study to Evaluate the Effect of Two Different Repeat Doses of GSK2190915 on the QTc Interval.

Phase 1
Withdrawn
Conditions
Asthma
Interventions
Drug: GSK2190915 100mg
Drug: GSK2190915 200mg
Drug: GSK2190915 placebo
First Posted Date
2012-11-04
Last Posted Date
2013-08-21
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT01721135
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

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