GlaxoSmithKline

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Public

Established: 1929-01-01

Employees: 70.2K

Market Cap: $90B

Website: http://www.gsk.com

Introduction: GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Clinical Trials

GSK706769 Repeat Dose Study

Phase 1

Completed

Conditions: Infection, Human Immunodeficiency Virus

Interventions: Drug: GSK706769
Other: Placebo

First Posted Date: 2008-07-08

Last Posted Date: 2017-08-03

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 40

Registration Number: NCT00711386

Locations: 🇺🇸
GSK Investigational Site, Madison, Wisconsin, United States

A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease

Phase 2

Completed

Conditions: Alzheimer's Disease

Interventions: Drug: Placebo
Drug: SB-742457 15mg
Drug: SB-742457 35mg
Drug: donepezil 5-10mg

First Posted Date: 2008-07-04

Last Posted Date: 2017-12-07

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 682

Registration Number: NCT00710684

Locations: 🇪🇸
GSK Investigational Site, Valencia, Spain

Lapatinib + Vinorelbine in ErbB2 Overexpressing, First or Second Line Metastatic Breast Cancer Subjects

Phase 2

Terminated

Conditions: Neoplasms, Breast

First Posted Date: 2008-07-03

Last Posted Date: 2014-07-14

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 44

Registration Number: NCT00709618

Locations: 🇺🇸
GSK Investigational Site, Memphis, Tennessee, United States

In Situ Caries Efficacy of Fluoride Toothpastes

Phase 3

Completed

Conditions: Caries

Interventions: Drug: NaF
Drug: Placebo
Drug: NaMFP

First Posted Date: 2008-07-02

Last Posted Date: 2015-01-01

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 57

Registration Number: NCT00708097

Locations: 🇺🇸
Indiana University School of Dentistry, Indianapolis, Indiana, United States

Study of SB-742457 or Donepezil Versus Placebo in Subjects With Mild-to-moderate Alzheimer's Disease

Phase 2

Completed

Conditions: Alzheimer's Disease

Interventions: Drug: SB-742457
Drug: Donepezil
Drug: Placebo

First Posted Date: 2008-07-02

Last Posted Date: 2018-07-27

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 576

Registration Number: NCT00708552

Locations: 🇿🇦
GSK Investigational Site, Sunninghill, South Africa

In Situ Caries of Fluoride Toothpastes

Phase 3

Completed

Conditions: Healthy Subjects
Partial Denture Wearers
Caries

Interventions: Drug: Sodium fluoride toothpaste
Drug: Placebo toothpaste

First Posted Date: 2008-07-02

Last Posted Date: 2013-04-22

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 60

Registration Number: NCT00708123

Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes

Phase 3

Completed

Conditions: Dental Caries

Interventions: Drug: Sodium Fluoride (NaF)
Drug: Placebo

First Posted Date: 2008-07-02

Last Posted Date: 2015-01-01

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 65

Registration Number: NCT00708305

Locations: 🇺🇸
Indiana University School of Dentistry, Indianapolis, Indiana, United States

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults.

Phase 2

Completed

Conditions: Tuberculosis

Interventions: Biological: Control vaccine with the adjuvant system.
Biological: Control vaccine with physiological saline
Biological: GSK's candidate Mycobacterium tuberculosis vaccine 692342