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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of GSK2330811 in Healthy Japanese Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Placebo
First Posted Date
2019-10-24
Last Posted Date
2021-05-24
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
9
Registration Number
NCT04138043
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

A Study of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Diphtheria, Pertussis and Tetanus (Tdap) Viruses Followed by a 2nd Dose of the RSV Vaccine to Healthy Non-Pregnant Women

Phase 2
Completed
Conditions
Respiratory Syncytial Virus Infections
Interventions
Biological: RSVPreF3 formulation 3
Drug: Placebo
Biological: Boostrix-ex-US
Biological: RSVPreF3 formulation 2
Biological: Boostrix-US
First Posted Date
2019-10-24
Last Posted Date
2024-08-21
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
509
Registration Number
NCT04138056
Locations
🇨🇦

GSK Investigational Site, London, Ontario, Canada

Single Dose Study to Investigate the Pharmacokinetics (PK) and Safety of Belimumab 200 Milligrams (mg) Intravenous and 200 mg Subcutaneous Via Auto-injector in Chinese Healthy Subjects

Phase 1
Completed
Conditions
Systemic Lupus Erythematosus
Interventions
First Posted Date
2019-10-23
Last Posted Date
2020-12-28
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
36
Registration Number
NCT04136145
Locations
🇨🇳

GSK Investigational Site, Shanghai, China

Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors

Phase 3
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Biological: GSK3196165 (Otilimab)
Biological: Sarilumab
Drug: csDMARDs
First Posted Date
2019-10-22
Last Posted Date
2023-07-17
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
550
Registration Number
NCT04134728
Locations
🇬🇧

GSK Investigational Site, Northwood, Middlesex, United Kingdom

Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level

Phase 3
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
First Posted Date
2019-10-21
Last Posted Date
2024-12-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
806
Registration Number
NCT04133909
Locations
🇬🇧

GSK Investigational Site, Wishaw, United Kingdom

Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Phase 3
Terminated
Conditions
Neoplasms, Head and Neck
Interventions
First Posted Date
2019-10-16
Last Posted Date
2024-07-10
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
315
Registration Number
NCT04128696
Locations
🇬🇧

GSK Investigational Site, Sutton, United Kingdom

Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

First Posted Date
2019-10-15
Last Posted Date
2025-01-03
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
209
Registration Number
NCT04126200
Locations
🇸🇪

GSK Investigational Site, Stockholm, Sweden

Study of Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline's (GSK)Respiratory Syncytial Virus (RSV)Maternal Unadjuvanted Vaccine in Healthy Pregnant Women (Aged 18 to 40 Years) and Their Infants

Phase 2
Completed
Conditions
Respiratory Syncytial Virus Infections
Interventions
Biological: RSV MAT 60 µg
Biological: RSV MAT 120 µg
Drug: Placebo
First Posted Date
2019-10-15
Last Posted Date
2021-12-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
534
Registration Number
NCT04126213
Locations
🇪🇸

GSK Investigational Site, Marbella, Spain

A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride

Phase 3
Completed
Conditions
Gingivitis
Interventions
First Posted Date
2019-10-11
Last Posted Date
2020-01-31
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
98
Registration Number
NCT04123665
Locations
🇺🇸

GSK Investigational Site, Fort Wayne, Indiana, United States

Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers

Phase 1
Terminated
Conditions
Pain
Interventions
Drug: Placebo
First Posted Date
2019-10-03
Last Posted Date
2024-03-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
21
Registration Number
NCT04114656
Locations
🇳🇱

GSK Investigational Site, Leiden, Netherlands

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