GlaxoSmithKline

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Public

Established: 1929-01-01

Employees: 70.2K

Market Cap: $90B

Website: http://www.gsk.com

Introduction: GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Clinical Trials

Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study

Phase 3

Completed

Conditions: Pain

Interventions: Drug: Diclofenac diethylamine 2.32% gel
Drug: Diclofenac diethylamine 1.16% gel
Other: Placebo

First Posted Date: 2019-08-12

Last Posted Date: 2022-04-12

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 313

Registration Number: NCT04052620

Locations: 🇨🇳
GSK Investigational Site, Shanghai, China

Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjects

Phase 1

Completed

Conditions: Cholestasis

Interventions: Drug: GSK2330672 (linerixibat)
Drug: Obeticholic acid

First Posted Date: 2019-08-12

Last Posted Date: 2020-07-24

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 19

Registration Number: NCT04053023

Locations: 🇬🇧
GSK Investigational Site, Cambridge, United Kingdom

A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks

Phase 4

Completed

Conditions: Gingivitis

Interventions: Drug: Sensodyne Repair and Protect
Drug: Colgate Cavity Protection

First Posted Date: 2019-08-08

Last Posted Date: 2020-11-19

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 130

Registration Number: NCT04050722

Locations: 🇺🇸
GSK Investigational Site, Las Vegas, Nevada, United States

Safety and Immunogenicity Study of GSK's Clostridium Difficile Vaccine 2904545A When Administered in Healthy Adults Aged 18-45 Years and 50-70 Years

Phase 1

Completed

Conditions: Clostridium Infections

Interventions: Biological: C. difficile investigational vaccine based on the F2 antigen (GSK2904545A)
Drug: Placebo
Biological: C. difficile investigational vaccine based on the F2 antigen (GSK2904545A) adjuvanted with AS01B

First Posted Date: 2019-07-19

Last Posted Date: 2023-10-12

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 140

Registration Number: NCT04026009

Locations: 🇧🇪
GSK Investigational Site, Gent, Belgium

Efficacy of Manual Toothbrushes in Removing Dental Plaque

Not Applicable

Completed

Conditions: Dental Plaque
Oral Hygiene

Interventions: Other: Oral B Indicator 123
Other: Dr Best Original
Other: Dr Best Multi Expert
Other: parodontax Interdental

First Posted Date: 2019-07-19

Last Posted Date: 2021-01-28

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 80

Registration Number: NCT04025684

Locations: 🇬🇧
GSK Investigational Site, Birmingham, West Midlands, United Kingdom

A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

Phase 3

Completed

Conditions: Urinary Tract Infections

Interventions: Drug: Gepotidacin
Drug: Nitrofurantoin
Drug: Placebo matching gepotidacin
Drug: Placebo matching nitrofurantoin

First Posted Date: 2019-07-16

Last Posted Date: 2023-06-22

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 1531

Registration Number: NCT04020341

Locations: 🇬🇧
GSK Investigational Site, Peterborough, United Kingdom

A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea

Phase 3

Completed

Conditions: Gonorrhea

Interventions: Drug: Ceftriaxone
Drug: Gepotidacin
Drug: Azithromycin

First Posted Date: 2019-07-08

Last Posted Date: 2024-05-30

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 628

Registration Number: NCT04010539

Locations: 🇬🇧
GSK Investigational Site, St Helens, United Kingdom

A Photoxicity and Photoallergy Study of a Developmental Face Cream, Serum and Lotion

Not Applicable

Completed

Conditions: Skin Care

Interventions: Other: Serum
Other: Lotion
Other: Cream
Other: Normal Saline

First Posted Date: 2019-07-05

Last Posted Date: 2021-08-13

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 40

Registration Number: NCT04006795

Locations: 🇧🇷
GSK Investigational Site, Campinas, São Paulo, Brazil

To Evaluate Skin Irritation and Skin Sensitisation of Developmental Cosmetic Facial Products

Not Applicable

Completed

Conditions: Skin Care

Interventions: Other: Lotion
Other: Cream
Other: Serum
Other: Normal Saline

First Posted Date: 2019-07-05

Last Posted Date: 2020-12-10

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 302

Registration Number: NCT04007159

Locations: 🇧🇷
GSK Investigational Site, Campinas, São Paulo, Brazil

A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant

Phase 2

Recruiting

Conditions: Herpes Zoster

Interventions: Biological: PED-HZ/su

First Posted Date: 2019-07-05

Last Posted Date: 2022-12-07

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 184

Registration Number: NCT04006808

Locations: 🇬🇧
GSK Investigational Site, Southampton, United Kingdom

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