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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants

Phase 1
Completed
Conditions
Hypertension, Pulmonary
Interventions
Drug: AMB new formulation (1 mg)
Drug: Reference AMB (5 mg)
First Posted Date
2019-09-19
Last Posted Date
2020-08-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
29
Registration Number
NCT04095286
Locations
🇬🇧

GSK Investigational Site, Cambridge, Cambridgeshire, United Kingdom

Safety and Immunogenicity Study of GlaxoSmithKline's Herpes Zoster Subunit Vaccine (HZ/su) When Given on a Two-dose Schedule to Adults at Least 50 Years of Age (YOA) With a Prior Episode of Herpes Zoster

Phase 3
Completed
Conditions
Herpes Zoster
Interventions
Biological: Herpes Zoster subunit (HZ/su) vaccine (GSK1437173A)
Drug: Placebo
First Posted Date
2019-09-16
Last Posted Date
2025-03-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1430
Registration Number
NCT04091451
Locations
🇬🇧

GSK Investigational Site, Trowbridge, United Kingdom

Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma

Phase 1
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2019-09-16
Last Posted Date
2025-03-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
118
Registration Number
NCT04091126
Locations
🇬🇧

GSK Investigational Site, Southampton, United Kingdom

A Study to Test GlaxoSmithKline's (GSK) Respiratory Syncytial Virus RSV Candidate Vaccine's Safety and Immune Response in Japanese Older Adults

Phase 1
Completed
Conditions
Respiratory Syncytial Virus Infections
Interventions
Drug: Placebo
Biological: RSV_PreF3 Vaccine (GSK3844766A) adjuvanted with AS01B
First Posted Date
2019-09-16
Last Posted Date
2022-02-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
40
Registration Number
NCT04090658
Locations
🇯🇵

GSK Investigational Site, Fukuoka, Japan

Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects

Phase 1
Completed
Conditions
Infections, Bacterial
Interventions
Drug: Placebo
First Posted Date
2019-09-06
Last Posted Date
2020-09-04
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
34
Registration Number
NCT04079790
Locations
🇺🇸

GSK Investigational Site, Las Vegas, Nevada, United States

A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Experimental Rabies Vaccine in Healthy Adults

Phase 1
Completed
Conditions
Virus Diseases
Interventions
Biological: Lower dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Biological: Medium dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Biological: Low dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Biological: Lowest dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Drug: Saline Placebo
Biological: RabAvert
First Posted Date
2019-08-20
Last Posted Date
2024-03-01
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
160
Registration Number
NCT04062669
Locations
🇺🇸

GSK Investigational Site, Rochester, New York, United States

Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study

Phase 3
Completed
Conditions
Pain
Interventions
First Posted Date
2019-08-12
Last Posted Date
2022-04-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
313
Registration Number
NCT04052620
Locations
🇨🇳

GSK Investigational Site, Shanghai, China

Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjects

Phase 1
Completed
Conditions
Cholestasis
Interventions
Drug: GSK2330672 (linerixibat)
First Posted Date
2019-08-12
Last Posted Date
2020-07-24
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
19
Registration Number
NCT04053023
Locations
🇬🇧

GSK Investigational Site, Cambridge, United Kingdom

A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks

Phase 4
Completed
Conditions
Gingivitis
Interventions
Drug: Sensodyne Repair and Protect
Drug: Colgate Cavity Protection
First Posted Date
2019-08-08
Last Posted Date
2020-11-19
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
130
Registration Number
NCT04050722
Locations
🇺🇸

GSK Investigational Site, Las Vegas, Nevada, United States

Safety and Immunogenicity Study of GSK's Clostridium Difficile Vaccine 2904545A When Administered in Healthy Adults Aged 18-45 Years and 50-70 Years

Phase 1
Completed
Conditions
Clostridium Infections
Interventions
Biological: C. difficile investigational vaccine based on the F2 antigen (GSK2904545A)
Drug: Placebo
Biological: C. difficile investigational vaccine based on the F2 antigen (GSK2904545A) adjuvanted with AS01B
First Posted Date
2019-07-19
Last Posted Date
2023-10-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
140
Registration Number
NCT04026009
Locations
🇧🇪

GSK Investigational Site, Gent, Belgium

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