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GlaxoSmithKline

GlaxoSmithKline logo
πŸ‡¬πŸ‡§United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Burden of Disease Among Subjects With Eosinophilic Chronic Obstructive Pulmonary Disease (COPD)

Completed
Conditions
Pulmonary Disease, Chronic Obstructive
First Posted Date
2018-02-19
Last Posted Date
2019-01-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
341
Registration Number
NCT03436511
Locations
πŸ‡ͺπŸ‡Έ

GSK Investigational Site, Valencia, Spain

A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects

Completed
Conditions
Cervical Intraepithelial Neoplasia
Interventions
Other: Safety data collection (following routine vaccination)
First Posted Date
2018-02-19
Last Posted Date
2021-09-08
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
3016
Registration Number
NCT03438006
Locations
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GSK Investigational Site, Shanghai, China

A Study to Investigate the Safety and Immunogenicity of Different Formulations of GSK Biologicals' Meningococcal ACWY Conjugate Vaccine (GSK3536820A and Menveo) Administered to Healthy Adolescents and Young Adults 10 to 40 Years of Age

Phase 2
Completed
Conditions
Meningitis, Meningococcal
Interventions
Biological: MenACWY
Biological: MenACWY liquid
First Posted Date
2018-02-14
Last Posted Date
2021-02-17
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1707
Registration Number
NCT03433482
Locations
πŸ‡ΉπŸ‡·

GSK Investigational Site, Izmir, Turkey

First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699

Phase 1
Terminated
Conditions
Arthritis, Rheumatoid
Interventions
Drug: GSK3358699
Drug: Placebo
Biological: GM-CSF
Biological: LPS
Other: Cantharidin
First Posted Date
2018-02-09
Last Posted Date
2020-12-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
48
Registration Number
NCT03426995
Locations
πŸ‡¬πŸ‡§

GSK Investigational Site, Cambridge, United Kingdom

Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging

Phase 1
Terminated
Conditions
Amyloidosis
Interventions
Drug: GSK2315698 (CPHPC)
Drug: GSK2398852 (unlabeled anti-SAP mAb)
Drug: 89Zr-GSK2398852 (89Zr-labeled anti-SAP mAb)
First Posted Date
2018-01-31
Last Posted Date
2019-08-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
2
Registration Number
NCT03417830
Locations
πŸ‡ΈπŸ‡ͺ

GSK Investigational Site, Uppsala, Sweden

To Investigate the Gastrointestinal Behaviour of Two Triple Combination Products in Healthy Male Volunteers

First Posted Date
2018-01-30
Last Posted Date
2019-06-24
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
28
Registration Number
NCT03415243
Locations
πŸ‡ΊπŸ‡Έ

GSK Investigational Site, Lexington, Kentucky, United States

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Phase 1
Completed
Conditions
Infections, Bacterial
Interventions
Drug: Test formulation A
Drug: Reference formulation B
First Posted Date
2018-01-24
Last Posted Date
2020-02-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
28
Registration Number
NCT03408392
Locations
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GSK Investigational Site, Bloemfontein, Free State, South Africa

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat in Non-Dialysis Subjects Evaluating Hemoglobin (Hgb) and Quality of Life (ASCEND-NHQ)

Phase 3
Completed
Conditions
Anaemia
Interventions
First Posted Date
2018-01-24
Last Posted Date
2024-04-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
614
Registration Number
NCT03409107
Locations
πŸ‡¬πŸ‡§

GSK Investigational Site, Swansea, United Kingdom

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Three-times Weekly Dosing in Dialysis (ASCEND-TD)

Phase 3
Completed
Conditions
Anaemia
Interventions
Drug: Matching placebo tablets
Drug: Daprodustat tablets
Drug: Saline vials or bags
Drug: Epoetin alfa vials
First Posted Date
2018-01-17
Last Posted Date
2021-07-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
407
Registration Number
NCT03400033
Locations
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GSK Investigational Site, Swansea, United Kingdom

Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)

Completed
Conditions
Wiskott-Aldrich Syndrome
Interventions
Other: Caregiver interview guide
Other: Patient Interview guide
Other: Sociodemographic questionnaire
Other: Pediatric quality of life (PedsQL) questionnaire
Other: Clinical questionnaire
First Posted Date
2018-01-16
Last Posted Date
2019-03-14
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
19
Registration Number
NCT03399461
Locations
πŸ‡ΊπŸ‡Έ

GSK Investigational Site, Collegeville, Pennsylvania, United States

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