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GlaxoSmithKline

GlaxoSmithKline logo
πŸ‡¬πŸ‡§United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Post-marketing Safety Monitoring Program of Fluticasone Propionate (FP) in Chinese Subjects With Asthma Aged 1 to <4 Years

Completed
Conditions
Asthma
Interventions
First Posted Date
2017-09-06
Last Posted Date
2019-10-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
158
Registration Number
NCT03273946
Locations
πŸ‡¨πŸ‡³

GSK Investigational Site, Shanghai, China

Subject Insights to Understand the Hand Osteoarthritis (HOA)

Completed
Conditions
Osteoarthritis
Interventions
Other: Michigan Hand Outcomes Questionnaire
Other: Real-time data capture app
First Posted Date
2017-09-05
Last Posted Date
2018-10-16
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
30
Registration Number
NCT03271203
Locations
πŸ‡¬πŸ‡§

GSK Investigational Site, Bollington, Cheshire, United Kingdom

Impact of Rotavirus Vaccination on Hospital Pressures at a Large Paediatric Hospital in the UK: an Ecological Study

Completed
Conditions
Gastroenteritis
Interventions
Other: No intervention
First Posted Date
2017-09-05
Last Posted Date
2017-09-21
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1
Registration Number
NCT03271593

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Phase 1
Completed
Conditions
Autoimmune Diseases
Interventions
Drug: GSK2982772 Modified Release
Drug: GSK2982772 Immediate Release
First Posted Date
2017-08-30
Last Posted Date
2021-08-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
45
Registration Number
NCT03266172
Locations
πŸ‡¬πŸ‡§

GSK Investigational Site, Nottingham, United Kingdom

A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices

Phase 2
Completed
Conditions
Oral Hygiene
Interventions
Drug: 5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica
Drug: 5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP
Drug: 5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica
Drug: 5% KNO3 / 0.2543% NaF dentifrice with 16% abrasive silica and 5% STP
First Posted Date
2017-08-30
Last Posted Date
2019-01-08
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
123
Registration Number
NCT03267511
Locations
πŸ‡ΊπŸ‡Έ

GSK Investigational Site, Fort Wayne, Indiana, United States

A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Clinical Activity of GSK525762 Plus Trametinib in Subjects With Solid Tumors

Phase 2
Withdrawn
Conditions
Solid Tumours
Interventions
Drug: GSK525762 Besylate tablets
Drug: Trametinib tablets
First Posted Date
2017-08-30
Last Posted Date
2017-12-08
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT03266159

A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity

Phase 3
Completed
Conditions
Spasticity, Post-Stroke
Interventions
Drug: Botulinum toxin A (GSK1358820)
Drug: Placebo
First Posted Date
2017-08-24
Last Posted Date
2020-06-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
124
Registration Number
NCT03261167
Locations
πŸ‡―πŸ‡΅

GSK Investigational Site, Yamagata, Japan

Phase I Study of Pyrimethamine in Healthy Japanese and Caucasian Subjects

Phase 1
Completed
Conditions
Toxoplasmosis
Interventions
First Posted Date
2017-08-23
Last Posted Date
2020-03-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
14
Registration Number
NCT03258762
Locations
πŸ‡¦πŸ‡Ί

GSK Investigational Site, Melbourne, Victoria, Australia

A Study of Switching From Entecavir to Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B

Phase 4
Completed
Conditions
Hepatitis B, Chronic
Interventions
First Posted Date
2017-08-23
Last Posted Date
2020-08-04
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
75
Registration Number
NCT03258710
Locations
πŸ‡―πŸ‡΅

GSK Investigational Site, Tottori, Japan

Randomized Study Evaluating the Effect of Danirixin on Neutrophil Extracellular Traps (NETs) in Chronic Obstructive Pulmonary Disease (COPD)

Phase 2
Terminated
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: Placebo
Drug: Danirixin
Drug: Rescue medication
Drug: Inhaled COPD maintenance medication
First Posted Date
2017-08-16
Last Posted Date
2021-03-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
19
Registration Number
NCT03250689
Locations
πŸ‡¬πŸ‡§

GSK Investigational Site, Dundee, United Kingdom

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